15 citations
,
June 2020 in “Applied Materials Today” This study found that SA-MS hydrogel released Mo4+ ions which promoted healing of disease-impaired wounds by enhancing cell proliferation and angiogenesis, and through its photothermal effects addressed skin cancer-impaired wounds in mice.
34 citations
,
July 2020 in “American journal of human genetics” This study identified mutations in the SREBF1 gene that impair SREBP1 function, potentially contributing to IFAP syndrome by affecting skin, hair, and eye development.
December 2023 in “Journal of Trace Elements in Medicine and Biology” This study found that nano-sized molybdenum accelerated hair growth and enhanced the effectiveness of minoxidil in a mouse model by reducing oxidative stress-related molecules.
7 citations
,
July 2008 in “Experimental Dermatology” This study identified molecular elements controlling the expression and stabilization of THH protein in hair follicle cells, revealing key mechanisms that support hair shaft development in mice.
1 citations
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December 2015 in “Lʹvìvsʹkij klìnìčnij vìsnik” This review discusses the connection between alopecia areata and trace element imbalances, noting deficiencies in elements like zinc and selenium, but reports no new clinical findings.
1 citations
,
January 2015 in “Trace Elements in Medicine (Moscow)” This case study reports that different organs, such as hair and stature, may grow at varying rates during different stages of growth.
96 citations
,
September 2017 in “Analytica Chimica Acta” This review discusses the growing use of scalp hair for elemental analysis in various fields and highlights advancements in analysis techniques, including the future potential of laser ablation ICP-MS, but reports no new clinical results.
1 citations
,
October 2024 in “FARMACIA” This study found that patients with age-related cataracts had significantly lower levels of manganese, selenium, vanadium, and zinc in their serum compared to healthy controls, with low serum selenium and zinc levels showing an independent association with an increased risk of cataracts.
This review discusses the association between hair element levels and autism spectrum disorder, reporting links between neurotoxic elements like mercury and lead and pathogenesis, alongside potentially protective roles for zinc and copper balance.
22 citations
,
January 2014 in “Biological & Pharmaceutical Bulletin” This study found that ginsenoside F2 may suppress hair cell apoptosis and improve hair growth outcomes in a DHT-induced hair loss model more effectively than finasteride.
72 citations
,
January 2003 in “American Journal of Pathology” This study found that the co-activator CBP enhances the agonistic action of hydroxyflutamide on androgen receptors, suggesting a mechanism for therapy resistance in prostate cancer.
40 citations
,
May 2014 in “PLoS ONE” This study suggests that chronic stress can lead to decreased skin pigmentation in mice by disrupting the skin's HPA axis, potentially making stress a risk factor for depigmentation.
May 2024 in “Tạp chí Y Dược học Cần Thơ” This research explored hair loss and regrowth, highlighting the use of animal models like mice and rats to better understand hair physiology, shedding cycles, and potential treatments, with implications for human application.
4 citations
,
December 2020 in “Mammalian genome” This study found that pelage abnormalities in Harlequin mutant mice are linked to severe AIF deficiency and associated with altered expression of genes related to hair structure.
2 citations
,
August 2013 in “The Lancet. Diabetes & endocrinology” This report discusses the FDA's third denial of approval for Aveed, a long-acting testosterone injection by Endo Pharmaceuticals, citing continued safety concerns including severe side effects.
4 citations
,
May 2017 in “Data in Brief” This study identified five potential molecular targets for future androgenetic alopecia therapy using genome-wide gene-expression investigations and bioinformatics analyses.
70 citations
,
August 2020 in “Nanomaterials” This review discusses the development of electrospun nanofibrous scaffolds for promoting angiogenesis in tissue engineering but notes that their clinical application beyond bone and skin repair is still limited.
34 citations
,
October 2011 in “Pathology Research International” This article reviews potential factors influencing Behçet's disease, like increased neutrophil functions, immunological changes, stress, and hormonal alterations, but it presents no new clinical results.
18 citations
,
March 2011 in “Archives of ophthalmology” This review of periocular tinea in children found that eyelash loss and prolonged misdiagnosis are common, highlighting the need for considering fungal infections in cases refractory to standard treatments.
9 citations
,
April 2018 in “Journal of trace elements in medicine and biology” This review presents the practice of using hair bioelement analysis to assess nutritional status or environmental exposure, proposing complex interactions and hypotheses regarding depression and autism but reports no new clinical results.
3 citations
,
May 2014 in “InTech eBooks” This review discusses the genetic and androgen-related factors in androgenetic alopecia, highlighting a specific polymorphism in the AR protein associated with male pattern hair loss, and reports no new clinical results.
June 2025 in “Histopathology” This study found that in superficial angiomyxomas, S100A4-positive mesenchymal niches may induce non-neoplastic adnexal epithelial growth, and highlighted evidence of mesenchymal-to-epithelial transition in eccrine duct branching, especially in Carney's complex cases.
65 citations
,
August 2016 in “Metabolic brain disease” This study found that children with autism spectrum disorder generally have lower levels of both essential and toxic trace elements in their hair compared to controls.
64 citations
,
July 2016 in “Cold Spring Harbor Perspectives in Medicine” The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.
10 citations
,
August 2023 in “Clinical Nutrition” This study found that exposure to certain elements during pregnancy, measured in maternal hair, was associated with increased risk of gestational diabetes and potential impacts on infant neurodevelopment, with elements like Ta, Re, and Se posing the highest risk for gestational diabetes.
5 citations
,
January 2007 in “Lincoln (University of Nebraska)” These investigations described in the study demonstrate how geochemical techniques can be applied to biological studies in Yellowstone, finding significant mercury accumulation in trout and grizzly bears which correlates with hydrothermal sources.
2 citations
,
January 2013 This review discusses various forensic applications of hair analysis, such as species identification and drug addiction testing, and reports no new study results.
18 citations
,
June 2017 in “Proceedings of the National Academy of Sciences of the United States of America” In this mouse study, hair growth defects associated with the Gk5 null allele were partially alleviated by simvastatin treatment, suggesting GK5 plays a key role in skin-specific cholesterol regulation.
3 citations
,
December 2019 in “Biomaterials Research/Biomaterials research” This study found that the concentrations of major inorganic elements in human scalp hair increase with age up to 25 years, and calcium and magnesium concentrations are significantly associated with sex in individuals over 20.
9 citations
,
May 2014 in “BMC medical genetics” In this case report, the authors suggest that a novel enhancer element's translocation near the TRPS1 gene may contribute to the TRPS phenotype, expanding understanding of the syndrome's genetic basis.