November 2023 in “Plants” This study evaluated compounds from Jatropha cordata bark, finding that a sterol mixture and n-heptyl ferulate demonstrated notable anti-inflammatory activity in murine macrophage cells without toxicity, suggesting potential for treating chronic inflammation.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, RNA integrity in horse hair follicles stored at various conditions in RNAlater® was maintained, showing that storing them at cool or room temperature for up to a week does not compromise RNA quality or concentration.
August 2023 in “Journal of Cosmetic Dermatology” In this study, injecting two different concentrations of botulinum toxin A was found to be safe and effective for treating androgenetic alopecia in Egyptian men and women, with improvements in hair grade and vellus hair density observed over six months.
August 2023 in “Tzu Chi Medical Journal” This study at a medical center in Eastern Taiwan found that female alopecia has diverse causes, including nutrient deficiencies, autoimmune diseases, psychological stress, thyroid conditions, and COVID-19 vaccination, with iron deficiency affecting 70.3% of cases.
August 2023 in “Innovare journal of Ayurvedic sciences” In this in vitro study, methanolic extracts of Mangifera indica and Hibiscus rosa-sinensis demonstrated significant inhibitory activity on α-amylase and α-glucosidase enzymes, suggesting their potential usefulness in diabetes management due to their comparable effects to the standard drug acarbose.
July 2023 in “International journal of life science and pharma research” In this study, a herbal hair cream containing extracts from Hibiscus rosa sinensis, Eclipta alba, and Solanum nigrum was developed, showing promising in-vitro inhibition of the 5α-reductase enzyme and potential benefits for alopecia treatment.
July 2023 in “Journal of the Mexican chemical society” This study found that Hibiscus rosa-sinensis dried leaves extract displayed the strongest pancreatic lipase inhibitory activity among 37 tested plant extracts, showing potential as an anti-obesity agent with effects comparable to the pharmaceutical drug orlistat in reducing plasma triacylglycerol levels in rats.
June 2023 in “International journal of pharmaceutical quality assurance” This study found that Eclipta alba extracts exhibit 5α-reductase inhibitory activity, with the methanolic extract showing a higher concentration of β-sitosterol compared to petroleum ether extract, indicating potential for treating androgenic conditions like male pattern baldness.
June 2023 in “Journal of Natural Remedies” This study found that the methanolic extract of Hibiscus rosa sinensis exhibits promising 5α-reductase inhibitory activity, suggesting its potential use in the treatment of androgenic conditions like male pattern hair loss and benign prostatic hyperplasia.
May 2023 in “Minia Journal of Medical Research” This study assessed vitamin D levels in both serum and hair among 80 male and female participants from a dermatology clinic and found no significant gender-related differences in these vitamin D levels.
May 2023 in “Journal of Pakistan Medical Association” This study found that women with polycystic ovary syndrome had significantly higher levels of serum and follicular fluid Gremlin-1 compared to healthy controls, suggesting potential diagnostic utility for these biomarker levels.
April 2023 in “International journal of research in Ayurveda and pharmacy” This study reported significant symptom improvement in a 30-year-old female with hypothyroidism after Ayurvedic treatment with Kanchnar twak kwath, Shunthi churna, and Nimb tail nasya, noting a reduction in TSH levels from 18.65 to 6.92 post-treatment.
April 2023 in “Clinical theriogenology” This report highlights the usefulness of specific diagnostic procedures, including penile/preputial cytology and transabdominal ultrasonography, in diagnosing cryptorchidism and Sertoli cell tumors in dogs with generalized skin conditions.
April 2023 in “Journal of Investigative Dermatology” In ex vivo organ culture of human scalp hair follicles, this study found that IL-9 signaling inhibits hair growth, reduces progenitor cell generation, and disrupts immune privilege.
March 2023 in “Journal of Cosmetic Dermatology” This case report illustrates that fibrosing alopecia in a pattern distribution may be misdiagnosed as androgenetic alopecia due to similar hair loss patterns, but distinctive trichoscopic and histopathologic features help differentiate it.
January 2023 in “International Journal of Contemporary Pediatrics” This case study describes a 5-year-old boy with vitamin D dependent rickets type 2, motor delays, and alopecia totalis who showed improved biochemical parameters with calcium and calcitriol treatment.
This study found that follicular unit extraction can be safely performed without bupivacaine and nerve blocks, using lignocaine with adrenaline as an effective anesthetic for patients with certain grades of androgenetic alopecia.
January 2023 in “International journal of clinical medicine” This study found that women with PCOS and androgenetic alopecia had significantly lower serum gelsolin levels compared to women with androgenetic alopecia but without PCOS.
January 2023 in “Advances in reproductive sciences” This study found that women with PCOS and female androgenetic alopecia had significantly higher serum pannexin-1 channel levels compared to those without PCOS, suggesting a potential role in hair loss etiology.
January 2023 in “Voennaâ medicina” This case study illustrates the successful treatment of chronic diffuse telogen effluvium in a young woman attributed to latent iron deficiency and emphasizes the importance of comprehensive assessment in similar cases.
January 2023 in “Indian Journal of Natural Products and Resources” This study found that the methanolic extract of Suaeda monodiana Maire exhibited antioxidant, antimicrobial, and photoprotective activities, suggesting its potential use in pharmaceutical formulations for treating skin diseases.
January 2023 in “Indian Journal of Unani Medicine” This report suggests that a Unani formulation, jawarish Falafali, effectively reduced symptoms and TSH levels in a 35-year-old woman with hypothyroidism over two months, while T3 and T4 levels remained normal.
January 2023 in “Journal of animal science/Journal of animal science ... and ASAS reference compendium” This study found that the novel culture condition gHFEM, which includes Y-27632 and bFGF, optimally promotes the proliferation and pluripotency of goat hair follicle stem cells in vitro.
December 2022 in “Journal of Pakistan Association of Dermatologists” In this study, PRP treatment for scalp hair restoration, combined with finasteride and minoxidil, resulted in reduced hair fall, stronger hair, and satisfactory regrowth in patients, with a satisfaction level of up to 90%.
December 2022 in “Research Square (Research Square)” This study found that an extract from the herbal medicine Ophioglossum vulgatum Linn. showed potential hair growth promotion and increased ATP and catalase activity in cell assays, suggesting its use in treating alopecia.
December 2022 in “International Journal of Women's Dermatology” This study reported that using the Sinclair Shedding Scale and intralesional corticosteroid injections may help diagnose and manage alopecia areata incognita in women experiencing excessive hair shedding without clear diagnostic indicators.
August 2022 in “Turkish journal of veterinary research” This study found that dogs with clinical demodicosis experienced oxidative stress, indicated by higher MDA (a marker of oxidation) and lower antioxidant levels, compared to control and post-treatment groups.
July 2022 in “International Journal of Health Sciences (IJHS) (En línea)” In this study, researchers found that serum dihydrotestosterone levels were significantly lower in individuals with Type 2 Diabetes compared to healthy controls, with 90% of diabetics displaying subnormal levels.
July 2022 in “Journal of Dermatology and Dermatologic Surgery” This study found that Vitamin B12 deficiency was more common in patients with chronic telogen effluvium than in healthy controls.
June 2022 in “Pham Ngoc Thach Journal of Medicine and Pharmacy” This study identified key natural compounds such as polyphenols and flavonoids in tongue fern and established optimal extraction conditions using methanol.