research The Role of 3Rs in the Age of One Health: Where We Are and Where We’re Going
Innovative methods are reducing animal testing and improving biomedical research.
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research Comparative Analysis of Machine Learning Algorithms in Diagnosis of Polycystic Ovarian Syndrome
The Random Forest algorithm was the most accurate at diagnosing Polycystic Ovarian Syndrome.
research Machine Learning Guided Discovery of Superoxide Dismutase Nanozymes for Androgenetic Alopecia
Machine learning identified promising nanozymes for treating hair loss.
research A Machine Learning-Based Scalp Hair Inspection and Diagnosis System for Scalp Health
The system can automatically identify different hair and scalp conditions using machine learning.
research Patient-Level Adverse Event Patterns in a Single-Institution Study of the Multi-Kinase Inhibitor Sorafenib
Sorafenib often causes mucositis, hand-foot syndrome, rash, alopecia, diarrhea, and fatigue.
research Editorial: Machine Learning Techniques on Gene Function Prediction Volume II
Machine learning is effective in predicting gene functions and their relationships with diseases.
research Scleromyxedema With Neurologic Involvement: Therapy With Intravenous Immunoglobulin
Umbilical cord blood transplantation improved the boy's symptoms despite complications.
research A Machine Learning and Network Framework to Discover New Indications for Small Molecules
The model successfully predicted new uses for existing drugs, like using certain hormonal and heart medications for respiratory and Parkinson's diseases, and a cancer drug for diabetes.
research Classification Framework for Healthy Hair and Alopecia Areata: A Machine Learning Approach
Machine learning can accurately identify Alopecia Areata, aiding in early detection and treatment of this hair loss condition.
research A Machine Learning and Network Framework to Discover New Indications for Small Molecules
A machine learning model called CATNIP can predict new uses for existing drugs, like using antidepressants for Parkinson's disease and a thyroid cancer drug for diabetes.
research The Hair Follicle: An Important Cellular Source in Tissue Engineering
Hair follicles are a key source of stem cells for skin repair and could help treat baldness.
research Machine Learning Approach for Predicting Systemic Lupus Erythematosus in Oman-Based Cohort
The machine learning model accurately predicts Systemic Lupus Erythematosus in Omani patients.
research Machine Learning-Based Steroid Metabolome Analysis in Women With Polycystic Ovary Syndrome Reveals Three Distinct Androgen Excess Subtypes With Different Metabolic Risk Profiles
Machine learning identified three unique subtypes of androgen excess in women with PCOS, each with different metabolic risks.
research A Machine Learning Algorithm Applied to Trichoscopy for Androgenic Alopecia Staging and Severity Assessment
The machine learning model effectively assesses the severity of hair loss and could help dermatologists with treatment decisions.
research Aberrant Connective Tissue Sheath Contraction Drives Premature Hair Follicle Regression by Inducing Progenitor Cell Depletion in Androgenetic Alopecia
Abnormal contraction of connective tissue in hair follicles causes hair loss by killing off important cells, and treating this could improve hair growth.
research Repigmentation by Combined Narrow-Band Ultraviolet B/Adipose-Derived Stem Cell Transplantation in the Mouse Model: Role of Nrf2/HO-1-Mediated Ca2+ Homeostasis
Combining narrow-band ultraviolet B light and stem cell transplantation helps repigmentation in vitiligo by maintaining calcium balance in mice.
research Proteome Analysis of Alpine Merino Sheep Skin Reveals New Insights into the Mechanisms Involved in Regulating Wool Fiber Diameter
Key proteins and pathways regulate wool fiber diameter in Alpine Merino sheep.
research Effects of Multiple Plasma Donations on Donors’ Biochemical Parameters
Multiple plasma donations do not change donors' biochemical parameters.
research Identification of Familial Infections Using Multilocus Microsatellite Typing in Tinea Corporis Due to Microsporum Canis
A mother and her two daughters got a skin infection from their cat.
research Larvicidal Potential, Antimicrobial Properties and Molecular Docking Analysis of Egyptian Mint (Mentha Rotundifolia) Against Culex Pipiens L. (Diptera: Culicidae) and Midgut-Borne Staphylococcus Aureus
Egyptian Mint effectively kills mosquito larvae and inhibits certain bacteria.
research Bioinformatics and Network Pharmacology Identify the Therapeutic Role and Potential Mechanism of Melatonin in Alzheimer's Disease and Rosacea
Melatonin could be an effective treatment for Alzheimer's Disease and rosacea.
research CFTR Potentiator Ivacaftor Protects Against Noise-Induced Hair Cell Loss by Increasing Nrf2 and Reducing Oxidative Stress
Ivacaftor can protect against noise-induced hearing loss by reducing oxidative stress.
research Melatonin Promotes Hair Regeneration by Modulating the Wnt/β-Catenin Signaling Pathway
Melatonin helps hair grow by activating a specific signaling pathway.
research Esrp1-Regulated Splicing of Arhgef11 Isoforms Is Required for Epithelial Tight Junction Integrity
The study concluded that specific proteins are necessary to maintain the structure that holds epithelial cells tightly together.
research Hair Transplantation on a Free Microvascular Latissimus Dorsi Flap
Hair transplants onto a scalp reconstruction flap improved appearance successfully.
research Mutational Spectrum in 101 Patients with Hypohidrotic Ectodermal Dysplasia and Breakpoint Mapping in Independent Cases of Rare Genomic Rearrangements
Researchers found genetic mutations causing hypohidrotic ectodermal dysplasia in 88% of studied patients and identified new mutations and genetic variations affecting the disease.
research Melatonin Alleviates Oxygen-Glucose Deprivation/Reperfusion-Induced Pyroptosis of HEI-OC1 Cells and Cochlear Hair Cells via MT-1,2/Nrf2/ROS/NLRP3 Pathway
Melatonin may protect inner ear cells from damage by reducing cell death and oxidative stress, potentially treating sudden hearing loss.
research IL-9 Mediated Human Primary Keratinocytes Invasion Is Dependent on MLC Controlled Contractility and Independent of MMP Activity
IL-9 increases skin cell movement but decreases their ability to invade, and this effect is controlled by cell contractility, not by MMPs.
research Transient Stimulation of TRPMLs Enhances the Functionality of HDPCs and Facilitates Hair Growth in Mice
Activating TRPMLs helps human cells important for hair growth and increases hair growth in mice.
research Dyeing Behavior of Yak Hair Fiber Treated with Microwave Low Temperature Plasma
Microwave plasma treatment improves yak hair dyeing.