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Topical JAK inhibitors may help treat some skin conditions but need more research.

LED therapy is safe and shows potential for treating skin conditions and promoting hair growth, but more research is needed.

Insulin resistance contributes to hormone imbalances in many women with polycystic ovary syndrome.

Hormone treatment for transgender patients may not need to be stopped before surgery, but more research is needed, especially on estrogen.

Tofacitinib is somewhat effective for alopecia areata, but more research is needed on its safety and long-term effects.

Androgen conjugates might be better indicators of skin sensitivity to hormones in women with excessive hair growth.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.

Psoriasis is linked to other autoimmune diseases and involves a specific inflammatory process.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Manatee whiskers are specially adapted for touch in water.

Melatonin improves cashmere goat hair growth and quality by increasing antioxidants and reducing cell death.

Certain metabolites are lower in women with PCOS and could be potential markers for the condition.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

Fat cells are important for tissue repair and stem cell support in various body parts.

Using psychological treatments can help manage skin conditions along with regular medical care.

Blocking JAK/STAT pathways can help treat hair loss from alopecia areata.

Stress from being transgender is linked to higher blood pressure at night and more inflammation, which may affect heart health.

Scientists created 3D hair-like structures that could help study hair growth and test treatments.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

The document suggests using standardized methods to track and measure hair loss in alopecia areata, including patient self-assessment and a 50% improvement in specific scores as a treatment goal.

Dutasteride more effectively treats hair loss than finasteride, but may increase risk of altered libido.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Severe vertex pattern hair loss may indicate a higher risk for artery plaque buildup.

The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.

Three drugs change mice's alcohol drinking patterns by affecting GABAA receptors.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

Finasteride and minoxidil together promote hair growth better than either alone.