1 citations
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July 2025 in “Dermatology Reports” This case report highlights a rare instance of syphilitic alopecia and ocular syphilis in an immunocompetent, HIV-negative woman, showing that syphilis-directed treatment led to symptom reversal, emphasizing the need to consider syphilis in the differential diagnosis for atypical alopecia.
2 citations
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April 2021 in “Journal of Cosmetic Dermatology” This study found that androgenetic alopecia significantly impacts young men's quality of life, affecting their self-esteem and daily functioning, and highlights the need for a specialized assessment tool.
69 citations
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April 2017 in “BMJ open” This study found that people with alopecia who worry about not wearing a wig reported higher levels of depression, anxiety, and social anxiety, although wig use increased social confidence for many.
3 citations
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May 2021 in “Molecules” This study found that men with early-onset androgenetic alopecia may experience less benefit from rosuvastatin treatment in terms of improving cardiometabolic risk factors compared to men with normal hair growth.
This study found that in an androgenetic alopecia mouse model, phospholipid-bile salt mixed micelles for topical Finasteride delivery improved hair regrowth and reduced systemic absorption compared to a hydroalcoholic solution, suggesting a safer and more effective treatment option.
October 2025 in “Frontiers in Medicine” This meta-analysis found that the combination of topical minoxidil-finasteride was more effective than minoxidil alone in improving hair density, hair diameter, and global photographic assessment for male androgenetic alopecia, though larger standardized trials are needed to confirm long-term outcomes.
January 2019 in “Egyptian Journal of Dermatology and Venereology /Egyptian Journal of Dermatology and Venerology” This study investigated the efficacy and safety of a gel combining topical calcipotriol and steroid for alopecia areata. It found the combination worked similarly to steroids alone in reducing hair loss, but with fewer side effects.
4 citations
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March 2022 in “Journal of cosmetic dermatology” This study concluded that a mixed preparation of piperine, capsaicin, and curcumin is effective for treating alopecia areata but is not superior to minoxidil over a short-term period.
June 2024 in “Skin Health and Disease” This study found that most men with alopecia experience significant psychosocial concerns, such as depleted confidence and lower wellbeing, yet seldom seek support, suggesting a disconnect likely influenced by masculine norms, particularly impacting those identifying as sexual minorities.
June 2020 in “Acta Scientific Otolaryngology” This case study presents a patient with male-pattern alopecia who received PRP treatment with calcium chloride after ruling out other potential causes.
May 2021 in “medical journal of mashhad university of medical sciences” This preliminary study found that combining 5% minoxidil with 2% flutamide was associated with increased hair thickness in patients with androgenetic alopecia compared to 5% minoxidil alone.
24 citations
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May 2013 in “Drug Design Development and Therapy” This pilot study found that a multimodal minoxidil microemulsion with diclofenac and tea tree oil was more effective and safer than minoxidil alone for treating androgenic alopecia over 32 weeks.
May 2013 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that a multimodal microemulsion containing minoxidil, diclofenac, and tea tree oil was significantly more effective and stable than minoxidil alone in treating androgenic alopecia over a 32-week period.
2 citations
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May 2025 in “BMJ Open” This study identified significant patient frustration with limited access to treatments for alopecia areata in Germany, exacerbated by the absence of health insurance reimbursement for necessary medications.
1 citations
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December 2022 in “Journal of cosmetic dermatology” This study found that combining a potent steroid with a vitamin D analogue may offer more convenient treatment for localized alopecia areata than using a superpotent steroid alone, with comparable efficacy but fewer side effects.
May 2026 in “Carbohydrate Polymer Technologies and Applications” This study found that the carbohydrate-based excipient β-cyclodextrin forms a stable inclusion complex with the active ingredient of Minoxicapil®, potentially enhancing its formulation for hair-loss treatment, and in vitro assays suggest improved proliferation of DPC cells, supporting its use in topical treatments.
4 citations
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May 2022 in “Frontiers in Medicine” The authors concluded that trichoscopic examination can be useful for diagnosing syphilitic alopecia in patients with idiopathic alopecia, though the findings are nonspecific and further studies are needed.
1 citations
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June 2025 in “Ukrains kyi Visnyk Psykhonevrolohii” This study found that psychopathological reactions, particularly cognitive impairments such as impaired concentration, are prevalent among patients with diffuse alopecia, with variations in prevalence linked to the genesis of alopecia, notably higher in mixed-type compared to metabolic-type alopecia.
1 citations
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March 2024 in “Psychiatry Neurology and Medical Psychology” This study examined the mental health of women with diffuse alopecia and found varied levels of mental maladjustment, with more patients with mixed alopecia showing adjustment disorders compared to those with metabolic alopecia. These findings could inform personalized treatment strategies for this condition.
June 2026 in “Psychosomatic Medicine and General Practice” In this study, women with metabolic and mixed-type alopecia showed different coping strategies; metabolic alopecia patients predominantly used adaptive strategies like problem-solving, while those with mixed alopecia often exhibited maladaptive strategies such as avoidance, with these behaviors being linked to higher levels of psychological maladjustment.
June 2026 in “Psychiatry Neurology and Medical Psychology” In this study, researchers found that women with mixed-genesis alopecia exhibited more significant psychological maladaptation and disturbances in self-attitude than those with metabolic alopecia, suggesting the importance of tailored psychotherapeutic approaches to improve their psychological adaptation and quality of life.
April 2026 in “Psychiatry Neurology and Medical Psychology” This study found that women with mixed alopecia exhibited significantly higher levels of depression, anxiety, and stress compared to those with metabolic alopecia, with these emotional disturbances closely linked to heightened mental maladaptation.
March 2026 in “Psychosomatic Medicine and General Practice” This study found that women with mixed alopecia had significantly lower levels of hardiness and resilience compared to those with metabolic alopecia, and these lower adaptive resources were associated with increased psychological maladaptation.
March 2026 in “Ukrains kyi Visnyk Psykhonevrolohii” In this study, female patients with mixed alopecia reported significantly lower quality of life compared to those with metabolic alopecia, with poorer psychological well-being and personal fulfillment, linked closely to mental maladaptation severity, suggesting a biopsychosocial treatment approach.
December 2024 in “Ukrains kyi Visnyk Psykhonevrolohii” This study found that women with mixed alopecia experienced significant cognitive impairments, particularly those with adaptation disorders, with symptoms like rapid fatigue and impaired concentration being most prevalent. The cognitive patterns are complex and require further investigation to inform tailored rehabilitation strategies.
June 2024 in “Ukrains kyi Visnyk Psykhonevrolohii” This study found that among women with diffuse alopecia, depressive symptoms were common, affecting more than a third of patients, particularly those with mixed alopecia, where the prevalence was three times higher compared to metabolic alopecia.
March 2024 in “Ukraïnsʹkij vìsnik psihonevrologìï” This study found that among women with diffuse alopecia, 47.7% exhibited psychopathological symptoms, with mixed alopecia patients showing more severe manifestations compared to those with metabolic alopecia, suggesting the need for personalized management strategies.
1 citations
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July 2024 in “Indian Journal of Sexually Transmitted Diseases and AIDS” In this study, a 38-year-old male with syphilis-related mixed pattern alopecia showed marked hair regrowth and resolution of postauricular lymphadenopathy after treatment with benzathine penicillin, suggesting that lymph node and hair examinations, along with trichoscopy, can aid in the diagnosis of alopecia syphilitica.
1 citations
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April 2010 in “Expert Review of Dermatology” This review discusses primary cicatricial alopecias, detailing their classification, pathogenesis, clinical features, histopathologic findings, and treatment, without reporting new experimental results.
90 citations
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June 2006 in “The American Journal of Dermatopathology” This review outlines the classification, histopathologic presentation, and pathogenetic concepts of scarring and nonscarring alopecias, reporting no new clinical results and emphasizing the need for clinicopathologic correlation.