176 citations,
January 2003 in “Journal of Investigative Dermatology” Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.
26 citations,
July 2007 in “Biochemical Pharmacology” ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.
356 citations,
March 2012 in “Trends in Plant Science” Auxin and ethylene hormones both work together and against each other to control plant growth.
90 citations,
January 2021 in “Clinical Endocrinology” Obesity increases the risk of developing polycystic ovary syndrome, and weight loss can improve the condition.
71 citations,
January 2015 in “The Scientific World Journal” Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.
59 citations,
March 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Smad-4 and Smad-7 are key in hair follicle development, with other Smads being less important.
43 citations,
August 2016 in “International Journal of Nanomedicine” Eupafolin nanoparticles help protect skin cells from damage caused by air pollution.
40 citations,
January 2013 in “Journal of Korean Medical Science” Iron deficiency may contribute to hair loss.
32 citations,
January 2005 in “Advances in Biochemical Engineering / Biotechnology” Fetal wounds heal without scarring because of different biological factors, which could help improve adult wound healing.
25 citations,
September 2014 in “Biological Research” Arctiin helps protect hair cells from damage and death caused by oxidative stress.
25 citations,
November 2012 in “Phytotherapy Research” Crataegus pinnatifida extract may help increase hair growth and thickness in mice.
24 citations,
December 2018 in “Life sciences” Lysophosphatidic acid is important for skin health and disease, and could be a target for new skin disorder treatments.
22 citations,
June 2018 in “Journal of Neuroinflammation” Procyanidins from grape seeds reduce nerve pain by blocking specific proteins and inflammation.
22 citations,
February 2008 in “Journal of Neurochemistry” Minoxidil prevents serotonin loss from MDMA by affecting potassium channels and increasing Akt phosphorylation.
21 citations,
April 2018 in “Journal of Dermatological Science” Cilostazol helps hair grow by making hair root cells grow faster and changing growth factor levels.
21 citations,
May 2015 in “The Journal of Steroid Biochemistry and Molecular Biology” Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.
21 citations,
February 2013 in “Clinics in Dermatology” New treatments for advanced skin cancer are improving patient outcomes, but drug resistance and finding the right treatment combinations are still big challenges.
20 citations,
March 2019 in “Nutrients” Rumex japonicus Houtt. may be an effective treatment for atopic dermatitis by reducing inflammation.
20 citations,
August 2014 in “PloS one” MED1 affects skin wound healing differently in young and old mice.
16 citations,
September 2020 in “British journal of dermatology/British journal of dermatology, Supplement” The article suggests that targeting specific immune pathways could help control and treat the skin disease hidradenitis suppurativa.
15 citations,
May 2007 in “Hormones and Behavior” Finasteride boosts morphine's pain relief, stops tolerance, and reduces withdrawal in rats.
12 citations,
May 2015 in “Molecular Medicine Reports” Troxerutin helps protect skin cells from oxidative stress and may be good for treating hair loss.
11 citations,
October 2020 in “Plant biotechnology journal” Overexpressing SIMK in alfalfa boosts root hair growth, nodule clustering, and shoot biomass.
5 citations,
December 2018 in “Biological & Pharmaceutical Bulletin” Norgalanthamine helps hair cells grow by activating certain pathways related to hair growth.
2 citations,
January 2018 in “Elsevier eBooks” Targeted therapies for lung cancer are effective but require careful management of side effects to benefit patients.
March 2021 in “Research Square (Research Square)” Patients with RASopathies have a higher risk of autoimmune disorders and should be routinely screened.
125 citations,
May 2019 in “Phytomedicine” Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.
42 citations,
April 2012 in “Seminars in Oncology” Targeted cancer therapies often cause skin problems that need careful management to improve patient quality of life and treatment success.
35 citations,
May 2015 in “Thrombosis Research” Prostaglandin E2 affects human platelet activity in complex ways that could lead to personalized heart disease treatments.
January 2018 in “Springer eBooks” Cancer treatments targeting specific cells often cause skin, hair, and nail problems, affecting patients' lives and requiring careful management.