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Biotin and biotinidase are essential to prevent health issues, and deficiencies require lifelong supplementation.

L-Cysteine may have health benefits, but its effectiveness is still debated due to limited clinical trial data.

Foxp1 helps control hair stem cell growth and response to stress during hair growth cycles.

Reactive oxygen species (ROS) help control plant growth and development.

Long-term use of azole antifungals can cause hair loss, hormonal imbalances, and severe skin reactions.

Probiotics show promise for health benefits but need more research to understand how they work.

Polydopamine is a safe, effective, and permanent hair dye that turns gray hair black in one hour.

Hydroxyl radicals cause hair follicle cell death during chemotherapy by reducing Bcl-2 protein levels.

Melatonin, usually known for sleep regulation, also has antioxidant properties that can protect skin, stimulate hair growth, and improve skin conditions, with topical application being more effective than oral use.

Thiazole, a sulfur and nitrogen chemical, is useful in creating potential drugs for conditions like seizures, cancer, bacterial infections, tuberculosis, inflammation, malaria, viruses, Alzheimer's, diabetes, and A1-receptor issues.

Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.

Synthetic antioxidants are effective, cheap, and stable, with some like zinc and cholecalciferol reducing child and cancer deaths, but the safety of additives like BHA, BHT, TBHQ, and PEG needs more research.

OR2AT4 helps reduce aging and cell damage in human skin cells.

Eating fewer calories may slow skin aging and improve skin health through various biological changes.

Cobalt is important for health but too much or too little can cause health problems, and its environmental buildup is a concern.

The enzyme pyruvate kinase M2 helps hair regrowth and could be a potential treatment for hair loss.

Intermittent fasting slows hair growth by damaging hair follicle cells.

YH0618 helps reduce chemotherapy-induced hair loss by targeting specific proteins and pathways.

One Ashwagandha extract may help protect cells with its antioxidant properties, while another could promote hair growth.

Equisetum debile extracts may help with skin whitening, anti-wrinkle, and anti-hair loss treatments.

Smoking may worsen hair loss, but more research is needed.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

More precise, personalized therapies are needed for autoimmune diseases.

Essential oils from Curcuma species, like turmeric, have compounds that can fight inflammation, cancer, and bacteria, and can also stimulate hair regrowth in bald males.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Licorice has many health benefits but should be used carefully due to possible side effects.

Modulating Cytochrome P450 activity could help develop new skin disease treatments.

Hormones like testosterone and estrogen significantly affect hair growth and structure.

Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.

PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.