May 2024 in “Clinical Cosmetic and Investigational Dermatology” Manipulating cell cleanup processes could help treat hair loss.
3 citations,
July 2023 in “International journal of molecular sciences” Stress may contribute to hair loss in alopecia areata by affecting immune responses and cell death in hair follicles.
202 citations,
August 2017 in “Nature cell biology” Lactate production is important for activating hair growth stem cells.
October 2023 in “Frontiers in endocrinology” Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.
May 2024 in “European Journal of Immunology” Vitamin B5 and coenzyme A may help regulate the immune system and could improve treatments for chronic diseases and cancer.
36 citations,
January 2019 in “Nature communications” High lactate dehydrogenase activity is not necessary for the growth of squamous cell carcinoma.
437 citations,
August 2014 in “Cell metabolism” Turning white fat into brown-like fat could help fight obesity and type 2 diabetes.
51 citations,
September 2020 in “Cell Metabolism” Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.
19 citations,
August 2019 in “Expert Opinion on Therapeutic Targets” New treatments for hair loss may target specific pathways and generate new hair follicles.
1 citations,
April 2021 in “Current Stem Cell Reports” Eating less can improve stem cell function and increase lifespan.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Blocking both main energy pathways can stop hair follicle stem cell-induced skin cancer growth.
5 citations,
February 2022 in “Acta Biomaterialia” Nanomaterials can improve hair care products and treatments, including hair loss and alopecia, by enhancing stability and safety, and allowing controlled release of compounds, but their safety in cosmetics needs more understanding.
166 citations,
November 2008 in “Expert Review of Endocrinology & Metabolism” Biotin and biotinidase are essential to prevent health issues, and deficiencies require lifelong supplementation.
59 citations,
May 2017 in “Scientific reports” ZDHHC13 is important for normal liver function and metabolism, affecting mitochondrial activity.
106 citations,
April 2010 in “ACS Nano” C60 fullerenes can alter protein function and may help develop new disease inhibitors.
1 citations,
October 2023 in “Life science alliance” Pantethine may boost the immune system's ability to fight sarcoma.
April 2024 in “International journal of molecular sciences” Combination pharmacotherapy is generally more effective for treating keloids and hypertrophic scars.
343 citations,
December 2008 in “Endocrine Reviews” Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.
25 citations,
May 2020 in “EMBO reports” Calcium is important for stem cell function and maintenance, especially in blood and skin cells.
January 2023 in “Pharmaceutics” AA–TF#15 significantly promotes hair regrowth and could be an effective treatment for androgenic alopecia.
September 2023 in “International journal of molecular sciences” Targeting lipid metabolism can help treat advanced, resistant cancers.
May 2023 in “Research Square (Research Square)” Shi-Bi-Man activates hair follicle stem cells and promotes hair growth by changing lactic acid metabolism and other cellular processes.
1 citations,
July 2023 in “Chinese Medicine” Shi-Bi-Man, a Traditional Chinese Medicine, helps grow hair by boosting lactic acid metabolism and activating hair follicle stem cells.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Blocking a key energy pathway in human hair follicles can trigger stress responses that stop cell growth.
Blocking the Mitochondrial Pyruvate Carrier causes stress in hair follicles, which can be reduced by an ISR inhibitor.
33 citations,
March 2018 in “Trends in cell biology” Metabolism plays a key role in determining stem cell fate.
1 citations,
November 2022 in “Journal of Investigative Dermatology” ALRN-6924 may prevent hair loss caused by chemotherapy.
19 citations,
January 2018 in “Scientific Reports” Non-immune factors play a significant role in alopecia areata.
June 2023 in “Plastic and Reconstructive Surgery – Global Open” Exosomes may improve skin, scars, hair growth, and fat grafts in plastic surgery, but more research is needed.
47 citations,
March 2019 in “Journal of immunology research” Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.