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The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

Targeted anticancer therapies can cause severe side effects similar to traditional chemotherapy, but with different types.

Stem cells are crucial for wound healing and understanding their role could lead to new treatments, but more research is needed to answer unresolved questions.

Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.

The study identified unique genes in hair follicle cells and their environment, suggesting these genes help organize cells for hair growth.

Human dermal stem cells can become functional skin pigment cells.

Melasma is now considered a skin aging disorder caused by sun exposure in people with a genetic tendency, which impacts treatment and prevention approaches.

Dermal fibroblasts have adjustable roles in wound healing, with specific cells promoting regeneration or scar formation.

New genetic locations explain much of hair color variation in Europeans.

Mutations in TBX3 cause horses to have more even hair color instead of Dun camouflage.

Polydopamine is a safe, effective, and permanent hair dye that turns gray hair black in one hour.

SDF-1/CXCL12 and its receptor CXCR4 are crucial for melanocyte movement in mouse hair follicles.

Genetic differences between young and old Tan sheep explain why their fleece changes from curly to straight as they age.

THSG from a Chinese plant helps with aging and related diseases.

3,4,5-tri-O-caffeoylquinic acid promotes hair growth by activating the β-catenin pathway.

CD34+ and CD34- melanocyte stem cells have different regenerative abilities.

New therapies for Birt–Hogg–Dubé syndrome are being developed based on understanding the FLCN gene's role.

Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.

Runx3 helps determine hair shape.

Hair becomes gray and thin as we age, and while most hair loss in older people is due to genetics, there's a chance for gray hair to regain color under certain conditions.

Reducing Tyrosinase prevents mature color pigment cells from forming in mouse hair.

Chinese domestic goats have unique genetic traits due to domestication and geographic isolation.

Fat under the skin releases HGF which helps hair grow and gain color.

Stopping mitochondrial respiration can prevent brain cancer spread in skin cancer patients, and plant compound β-sitosterol could help achieve this.

Melatonin affects skin and hair color and protects skin cells, with potential benefits for hair growth and skin health.

Hair graying may be caused by stem cell depletion from stress or melanocyte damage.

Non-coding RNAs are crucial for skin development and health.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

A3B5 can reduce skin pigmentation and slow melanoma growth.