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Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.

The research shows that a gene called Wnt3 affects hair growth and structure, causing short hair and balding when overactive.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Nerves are crucial for the regeneration of various body parts in many animals.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

Wnt ligands are crucial for hair growth and repair.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Estrogen therapy can reduce skin aging but has cancer risks.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Thyroid hormones help hair grow, reduce hair loss, and increase hair pigment.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

Minoxidil helps hair growth by activating the β-catenin pathway.

Versican, a protein, is less present in thinning hair follicles and this decrease might contribute to common hair loss in men.

TCDD speeds up skin barrier formation by increasing certain gene expressions.

TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.

The article concludes that better understanding gene regulation related to seasonal changes can offer insights into the mechanisms of seasonal timing in mammals.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.