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510-540 / 1000+ resultsresearch Additional file 3 of ROS-responsive hydrogel-delivered miR-665 targets STAT3 to alleviate inflammation and promote hair follicle regeneration in alopecia areata
research Additional file 3 of ROS-responsive hydrogel-delivered miR-665 targets STAT3 to alleviate inflammation and promote hair follicle regeneration in alopecia areata
research Additional file 2 of ROS-responsive hydrogel-delivered miR-665 targets STAT3 to alleviate inflammation and promote hair follicle regeneration in alopecia areata
research Additional file 2 of ROS-responsive hydrogel-delivered miR-665 targets STAT3 to alleviate inflammation and promote hair follicle regeneration in alopecia areata
research HOTTIP Mediated Therapy Resistance in Glioma Cells Involves Regulation of EMT-Related miR-10b
This study found that the overexpression of the lncRNA HOTTIP in glioma cells increased resistance to the chemotherapy drug temozolomide, suggesting a key role for miR-10b and EMT processes in this resistance.
research Micro‐RNA‐31 controls hair cycle‐associated changes in gene expression programs of the skin and hair follicle
In this study, miR-31 was found to play a significant role in hair cycle regulation in mice by controlling key gene expressions involved in hair growth and differentiation.
research Scarless wound healing: finding the right cells and signals
This review discusses recent advancements in scar reduction techniques, highlighting promising therapeutic targets and the role of Wnt/β-catenin signaling in promoting scarless wound healing, but reports no new clinical results.
research MicroRNA-214 controls skin and hair follicle development by modulating the activity of the Wnt pathway
This study found that overexpression of miR-214 in keratinocytes inhibits hair follicle development and cycling by targeting β-catenin in the Wnt signaling pathway.
research Inducible deletion of epidermal Dicer and Drosha reveals multiple functions for miRNAs in postnatal skin
This study found that deleting the miRNA processing enzymes Drosha and Dicer from mouse skin epithelial cells disrupted normal hair follicle development and maintenance, leading to follicular degradation and stem cell loss during the growth phase.
research Human Amniotic Fluid Stem Cell-Derived Exosomes as a Novel Cell-Free Therapy for Cutaneous Regeneration
This study suggests that exosomal miRNAs from human amniotic fluid stem cells may inhibit myofibroblast differentiation and reduce fibrotic scarring in wound healing.
research MicroRNA/mRNA regulatory networks in the control of skin development and regeneration
This review discusses the role of miRNA/mRNA regulatory networks in skin development, epidermal homeostasis, and tissue remodeling, and suggests potential for miRNA-based therapies in treating skin conditions, but reports no new clinical results.
research MicroRNA Species in Follicular Fluid Associating With Polycystic Ovary Syndrome and Related Intermediary Phenotypes
This study found that miRNA expression profiles in follicular fluid are altered in women with PCOS, with certain miRNAs potentially useful for distinguishing patient subtypes and contributing to understanding PCOS heterogeneity.
research MicroRNAs in the skin: role in development, homoeostasis and regeneration
This review discusses the role of microRNAs in skin function and potential therapeutic applications, emphasizing their importance in wound healing and disease management, though it reports no new experimental findings.
research Differential expression analysis of balding and nonbalding dermal papilla microRNAs in male pattern baldness with a microRNA amplification profiling method
This study found that four microRNAs, which were significantly upregulated in balding hair follicle papilla cells, could play a role in the development of male pattern baldness.
research miR‐124 promotes neural differentiation in mouse bulge stem cells by repressing Ptbp1 and Sox9
This study found that miR-124 may facilitate the differentiation of hair follicle stem cells into neuronal cells by targeting Sox9 and Ptbp1.
research Exosomal miRNA-181a-5p from the cells of the hair follicle dermal papilla promotes the hair follicle growth and development via the Wnt/β-catenin signaling pathway
This study found that exosomal miR-181a-5p promotes hair follicle growth and development in vitro by activating the Wnt/β-catenin signaling pathway and suppressing hair follicle stem cell apoptosis.
research Lysophosphatidic acid increases the proliferation and migration of adipose-derived stem cells via the generation of reactive oxygen species
This study found that lysophosphatidic acid increases mesenchymal stem cell proliferation and migration through signaling pathways and reactive oxygen species, implicating potential applications in stem cell expansion.
research Current insight into the functions of microRNAs in common human hair loss disorders: a mini review
MicroRNAs may help diagnose and treat hair loss disorders.
research The Molecular Revolution in Cutaneous Biology: Noncoding RNAs: New Molecular Players in Dermatology and Cutaneous Biology
This review highlights recent advances in understanding how non-coding RNAs, particularly miRNAs and lncRNAs, regulate skin development and homeostasis, but reports no new clinical results.
research Analysis of the microRNA expression profile of normal human dermal papilla cells treated with 5α-dihydrotestosterone
This study found that DHT treatment led to reduced cell growth, increased cell death, cell cycle arrest, ROS production, and senescence in normal human dermal papilla cells, potentially mediated by altered miRNA expression.
research Morphogenesis, Growth Cycle and Molecular Regulation of Hair Follicles
This review covers the structure, development, cycle, and molecular regulation of hair follicles but does not report new results, aiming to offer insights for addressing hair follicle-related diseases.
research miR‑339‑5p negatively regulates loureirin A‑induced hair follicle stem cell differentiation by targeting DLX5
This study found that miR-339-5p negatively regulates loureirin A-induced differentiation of hair follicle stem cells, potentially impacting skin repair and regeneration by inhibiting the Wnt/β-catenin signaling pathway.
research Interplay of MicroRNA-21 and SATB1 in Epidermal Keratinocytes during Skin Aging
The researchers reported that miR-21 expression increases with age in both human and mouse skin and may contribute to skin aging by targeting the chromatin remodeler SATB1 in keratinocytes.
research Activation and regulation of the granulation tissue derived cells with stemness-related properties
This study found that dermal stem cells from granulation tissue promoted wound healing and reduced fibrosis in a combined radiation and skin wound mouse model.
research Dermal Papilla Cell-Derived Extracellular Vesicles Increase Hair Inductive Gene Expression in Adipose Stem Cells via β-Catenin Activation
This study found that early passage dermal papilla cell-derived extracellular vesicles, combined with specialized medium, helped adipose-derived stem cells develop dermal papilla-like properties.
research Vitamin A alleviates heat stress‐induced damage to hair follicle development in Rex rabbits
This study found that adding vitamin A to the diet improved hair follicle density and fur quality in heat-stressed Rex rabbits, involving specific signaling pathways.
research Defining microRNA signatures of hair follicular stem and progenitor cells in healthy and androgenic alopecia patients
In this study, miR-324-3p was found to promote differentiation and migration in cultured keratinocytes and is highlighted as a potential target for treating androgenic alopecia.
research LncRNA H19 Overexpression Activates Wnt Signaling to Maintain the Hair Follicle Regeneration Potential of Dermal Papilla Cells
This study suggests that the long noncoding RNA H19 helps dermal papilla cells maintain their hair follicle-inducing ability by activating the Wnt signaling pathway, potentially offering a therapeutic target for androgenetic alopecia.
research Association of single nucleotide polymorphisms in the RAB5B gene 3′UTR region with polycystic ovary syndrome in Chinese Han women
In this study, single nucleotide polymorphisms in the RAB5B gene were linked to an increased risk of polycystic ovary syndrome and associated with specific microRNA binding sites.