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This study found that transfecting alpaca melanocytes with miR-5110 altered gene expression related to pigmentation, specifically identifying pathways like MAPK and Wnt as involved in melanogenesis regulation, providing insights into miR-5110's role in pigmentation processes.

Developing microRNA-based treatments is hard but has potential.

This study found that chi-miR-30b-5p was more expressed in the telogen phase than in the anagen phase and inhibited dermal papilla cell proliferation by targeting CaMKIIδ.

This study found that intrinsic feedback loops are crucial for maintaining the function of human dermal papilla cells during hair growth, highlighting the importance of autocrine signaling and niche reprogramming for advancing hair follicle biology and regenerative therapies for hair loss.

In this study, researchers demonstrated that in a mouse model, the stimulation of mammary tumor growth due to progesterone is primarily caused by its metabolite, 5αP, not progesterone itself.

This study found that microRNA levels in hair shafts were significantly decreased in scleroderma patients compared to normal subjects, suggesting they may serve as effective biomarkers.

This study reported that the IL1A 4-bp indel polymorphism is associated with a reduced risk of alopecia areata in Chinese populations, possibly through miR-122 mediated regulation of IL-1α expression.

This study reports that miR-302 promotes pluripotency by inhibiting NR2F2 and indirectly regulating OCT4 in stem cells, enhancing reprogramming efficiency when added to traditional factors.

This study proposes the miR-22-5p-LEF1 axis as a novel pathway that may regulate hair follicle stem cell proliferation.

This study reported that specific non-coding RNAs may regulate the hair follicle cycle in Angora rabbits by acting as competitive endogenous RNAs, enhancing understanding of ncRNA roles in hair growth.

This article reviews the role of microRNAs as epigenetic modulators in dermatology but reports no new clinical findings.

This review discusses the identification and roles of different epidermal stem cell types in skin homeostasis and repair, and reports no new experimental findings.

This study identified specific miRNAs and mRNAs involved in the development of secondary hair follicles in cashmere goats, particularly noting a targeted relationship between chi-miR-30e-5p and DLL4.

In this study, researchers found that microRNAs and specific target genes, such as MiR-195 and genes like CHP1, SMAD2, FZD6, and SIAH1, play significant roles in regulating hair follicle initiation in cashmere goats.

This study suggests that prenatal exposure to THC may negatively impact ovarian health in rats by altering miRNA expression, potentially leading to reproductive issues such as subfertility or premature reproductive senescence.

This study suggests that miR-144 influences hair follicle dynamics through its impact on Lhx2, which could lead to advancements in cashmere production, fleece quality, and treatments for hair growth disorders.

This study found that in Liaoning cashmere goats, overexpression of the PIP5K1A gene enhances skin fibroblast proliferation, while interference with this gene reverses melatonin-induced proliferation, and PIP5K1A regulates certain miRNA expressions, suggesting a role in improving cashmere yield and quality.

This study identified and analyzed numerous lncRNAs, miRNAs, and mRNAs involved in hair follicle development in cashmere goats, highlighting key regulatory pathways and suggesting roles for specific RNAs in enhancing hair follicle cell proliferation.

This study observed that two patients treated with interferon α-2b and ribavirin for chronic hepatitis C experienced complete and reversible straightening of their natural curly hair, which recurred with treatment resumption.

MicroRNA-21 could help diagnose and treat skin fibrosis.

This study found that the enhancer of zeste homolog 2 (EZH2) may promote hair growth by increasing STK40 expression and facilitating hair follicle stem cell proliferation and differentiation.

This review discusses the role of lncRNA Xist in cell growth regulation and disease development, particularly cancer, and reports no new experimental results.

This study expands knowledge of non-coding RNAs in goats and other mammals, enhancing understanding of their roles in hair follicle growth and regression.

This study found that miR-432 inhibits KRT83 expression, revealing potential molecular mechanisms for the formation of curly fleece in Tan sheep and suggesting implications for understanding curly hair formation in humans.

This study demonstrates that the transcription factor DLX5 can promote hair follicle stem cell differentiation through regulating the c-MYC/miR-29c-3p/NSD1 axis.

In this study, researchers found that miR-143-3p may play a novel role in cashmere growth by directly repressing the expression of Itga6 in secondary hair follicles of goats.

This study found that the MIR34A rs2666433 (A/G) variant is linked to increased risk and severity of alopecia areata, and high circulatory miR-34a levels may play a role in the disease's pathogenesis.

This study found that treating cashmere goat kids with melatonin significantly increased secondary hair follicle density, improving cashmere quality and yield, likely through mechanisms involving the MAPK signaling pathway.

This study found that miR-148a plays a significant role in regulating skin homeostasis and hair follicle cycling, influencing stem cell activity and development in mice.

This study observed distinct plasma miRNA profiles in alopecia areata, identifying several miRNAs downregulated in both mild and severe forms; machine learning models demonstrated strong predictive accuracy, and kinase inhibitors were suggested as promising therapeutic targets based on pathway analysis.