research Identification of Blood MicroRNA Alterations in Patients With Severe Active Alopecia Areata
Certain blood miRNAs are linked to severe alopecia areata and could lead to new treatments.
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780-810 / 1000+ results research Prevalent Founder Mutation c.736T>A of LIPH in Autosomal Recessive Woolly Hair of Japanese Leads to Variable Severity of Hypotrichosis in Adulthood
A specific gene mutation in Japanese people can cause varying degrees of hair thinning in adulthood.
research Isolated Autosomal Recessive Woolly Hair/Hypotrichosis: Genetics, Pathogenesis, and Therapies
Topical minoxidil may help treat a rare genetic hair condition with no fully effective treatments yet.
research Engineered Extracellular Vesicle Mimetics from Macrophage Promotes Hair Growth in Mice and Human Hair Follicle Growth
Engineered vesicles from macrophages help hair growth in mice and humans.
research Three Months Extended-Release Microspheres Prepared by Multi-Microchannel Microfluidics in Beagle Dog Models
A new device, IVL-PPF Microsphere®, was created to deliver a hair loss drug for up to 3 months with one injection, potentially replacing daily pills.
research Advances in Alopecia Areata and Androgenetic Alopecia
research Engineered Exosomes Biopotentiated Hydrogel Promote Hair Follicle Growth via Reprogramming the Perifollicular Microenvironment
The new hydrogel treatment promotes faster hair growth and better skin health for hair loss.
research Clinical Characterization and Treatment Response of Folliculitis Decalvans Lichen Planopilaris Phenotypic Spectrum: A Retrospective Series of 31 Patients
This type of hair loss is probably often missed and treatments reducing inflammation might work well.
research Comprehensive Analysis of the Circular RNA Expression Profile and CircRNA–miRNA–mRNA Network in the Goat Skin with Divergent Wool Curvature
Certain circular RNAs are crucial for wool growth and curvature in goats.
research Oral Minoxidil Therapy in Hair Loss: Where Do We Stand?
Oral minoxidil is effective for various hair loss types and may improve male sexual function, but aspirin can reduce its effectiveness.
research Active Pharmaceutical Ingredient-Ionic Liquids Assisted Follicular Co-Delivery of Ferulic Acid and Finasteride for Enhancing Targeted Anti-Alopecia
The new delivery system improves treatment for hair loss by enhancing drug absorption and effectiveness.
research The FRZB Gene Regulates Hair Follicle Development in Rabbits via the Wnt/β-Catenin Signaling Pathway
The FRZB gene slows hair growth in rabbits.
research Case of Autosomal Recessive Woolly Hair/Hypotrichosis with Compound Heterozygous Mutations in the LIPH Gene at c.742C > A and c.614A > G: The First Japanese Case
The first Japanese case of a genetic hair disorder caused by specific mutations in the LIPH gene was identified.
research Mechanical Anisotropy of Hair Affected by Genetic Diseases Highlights Structural Information Related to Differential Crosslinking in Keratins
research Design of a New Molecule Proven to Be Safe and Effective for Topical Depigmenting and Antiaging Method
A new molecule was found to be a safe and effective skin lightener and anti-aging product.
research An Integrative Analysis of the LncRNA-MiRNA-mRNA Competitive Endogenous RNA Network Reveals Potential Mechanisms in the Murine Hair Follicle Cycle
The research found new potential mechanisms in mouse hair growth by studying RNA interactions.
research Study of Cross-Referrals to the Dermatology Department in an Inpatient Setting at a Tertiary Care Center
Dermatology referrals improve patient care, but non-dermatologists need better training in skin conditions.
research Association Between Hair Proliferation and Flavonoid Silibinin in Human Dermal Papilla Cells
Silibinin may help promote hair growth and treat hair loss.
research Y27632 Promotes Proliferation via EGFR Signaling in a Newly Isolated and Characterized Human Primary Sebocyte Cell Line
Y27632 increases cell growth through EGFR signaling, not ROCK1/2.
research Compound Heterozygous Mutations in Forkhead Box N1 (FOXN1) Lead to Severe Immunodeficiency but Normal Hair and Nail Development in Patients
Mutations in the FOXN1 gene cause severe immune issues but don't affect hair and nails.
research Patients with Compound Heterozygous Mutations in Forkhead Box N1 Have Severe Immunodeficiency While Maintaining Normal Skin and Hair Development
Patients with certain FoxN1 gene mutations have severe immune issues but normal skin and hair.
research DNA Methylation Mediates LncRNA2919 Regulation of Hair Follicle Regeneration
DNA methylation controls lncRNA2919, which negatively affects hair growth.
research Genome-Wide Association Study in Alopecia Areata Implicates Both Innate and Adaptive Immunity
Alopecia areata involves both innate and adaptive immunity, with specific genes linked to the disease.
research Fibroblasts: Origins, Definitions, and Functions in Health and Disease
Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.
research Wnt/β-Catenin Signaling: Function, Biological Mechanisms, and Therapeutic Opportunities
The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
research Polycystic Ovary Syndrome (PCOS): An Inflammatory, Systemic, Lifestyle Endocrinopathy
PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.
research Lymphocytes, Neuropeptides, And Genes Involved In Alopecia Areata
Alopecia areata is an autoimmune disease where T cells attack hair follicles.
research Hopes and Limits of Adipose-Derived Stem Cells and Mesenchymal Stem Cells in Wound Healing
ADSCs help in wound healing and skin regeneration but need more research for full understanding.
research Maintenance of Hair Follicle Immune Privilege Is Linked to Prevention of NK Cell Attack
Hair follicles prevent NK cell attacks to avoid hair loss.
research Epigenetics of Colorectal Cancer
Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.