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This study identified a crucial Gli2-Serpinh1 regulatory axis that regulates fibroblast state transitions during skin wound healing, shedding light on fibroblast heterogeneity and suggesting potential precision regenerative therapies.

This review highlights that surface mechanical regulation can program macrophage behavior through specific mechanical cues on material surfaces, potentially advancing immunotherapies and regenerative medicine by enabling precise control over macrophage functions.

This review explores how various skin cell types contribute to photoaging driven by UV radiation, detailing their interactions and molecular mechanisms like oxidative stress and ECM degradation, ultimately offering insights for future anti-photoaging strategies.

This review highlights LTBP1 as a critical integrator in disease processes, showing its dual role in cancer progression and suppression, its pathological influence in fibrosis, and its contribution to various disorders, suggesting its potential as a biomarker and therapeutic target.

This review suggests that induced pluripotent stem cells (iPSCs) hold promise for treating chronic wounds, but further work is needed to address safety, efficacy, and translation from preclinical models to real-world applications.

In this review, researchers detail how immunosenescence and chronic neuroinflammation contribute to Parkinson's disease progression, exploring potential therapeutic strategies targeting this axis, such as senolytic agents and immune rejuvenation, while highlighting associated challenges and future research needs.

This review synthesizes current research on how the interaction between the skin microbiome and exosome-mediated communication influences hair disorders, and discusses how microbiome restoration and exosome-based therapies could advance treatments for conditions like alopecia by promoting hair regrowth and follicular health.

This review discusses strategies to identify, prevent, and manage complications in FUE and reports no new clinical results.

This review highlights the potential of wedelolactone from the plant Wedelia Chinensis, summarizing its reported pharmacological effects, including anti-inflammatory, antiviral, antibacterial, antitumor, anti-osteoporosis activities, and organ protection based on existing in vitro and in vivo research findings.

This review highlights icariin’s potential to regulate macrophages in varying conditions, discussing its effects on macrophage polarization, metabolism, and disease mechanisms, and noting the development of delivery systems to enhance its therapeutic impact.

This review summarizes recent advances in nanomedicine-based therapies for psoriasis, highlighting their potential to provide targeted and sustained therapeutic effects by modulating key cellular components and signaling pathways involved in the disease, offering novel perspectives for future treatment development.

This study found that miRNA-24 downregulates the KLF6 gene, influencing coat color by affecting melanogenesis pathways in Cashmere goats, and that miRNA-24 inhibition increased melanin content in mice.

This review explores the roles of superoxide dismutases in cellular processes and cancer, highlighting the potential of SOD mimetics in enhancing cancer treatment strategies, but it reports no new clinical findings.

In this study on mice, researchers observed that dermal white adipose tissue (dWAT) plays a key role in regulating skin inflammation and tissue repair; however, reduced expression of certain cytokines in obese mice may hinder these processes, indicating potential metabolic disruptions in dWAT during inflammation.

This study reviewed recent advancements in using botulinum toxin for treating androgenetic alopecia and emphasized the need for further research to determine the most effective injection sites and depths, as current strategies show inconsistent results.

This review highlights the potential of extracellular vesicles derived from medicinal plants as therapeutics for diseases such as cancer and inflammation, suggesting they may enhance the clinical use of herbal preparations, despite the challenges posed by extract complexity and individual variability.

This study examined the molecular communication in psoriasis cells, highlighting unique immune cell interactions and identifying new features of the hair follicle cell-psoriasis axis. It suggests the potential for targeted therapies at the single-cell level to improve psoriasis treatment.

This review highlights the crucial role of histone modification in the pathogenesis and treatment of chronic inflammatory skin diseases, and explores therapeutic strategies targeting these epigenetic changes to improve management of conditions such as psoriasis and atopic dermatitis.

In this review, researchers reported that Psoralea corylifolia, extensively used in Ayurveda and Traditional Chinese Medicine, exhibits various pharmacological activities, including antioxidant and antidiabetic effects, and is primarily used for treating skin diseases. The authors suggest further clinical trials to explore its therapeutic potential.

This study found that vimentin is essential for proper wound healing and cell growth by influencing EMT signaling and mTOR activity in mice.

Adipose-derived stem cells can be transformed into hair-forming cells using specific extracellular vesicles, offering potential for hair regeneration therapies.

This dissertation reported that the loss of Ovol2 impairs hair follicle regeneration and wound repair in mice, highlighting its role in regulating directional migration of epithelial cells.

This review discusses strategies to enhance mesenchymal stem cell therapy effectiveness but reports no new clinical results; it highlights the need for improved consistency and efficacy in MSC-based treatments.

This source reviews the role of exosomes in regenerative medicine, highlighting their ability to mediate cell communication and transport biomolecules to enhance or impair biological functions, with potential applications in tissue repair and regeneration.

This study found that hair follicles in mice and humans can convert wound-related myofibroblasts into adipocytes, suggesting a potential pathway to reduce scar formation by activating BMP signaling.

This study found that adipose-derived mesenchymal stem cells produced more anti-inflammatory and pro-angiogenic cytokines on electrospun scaffolds, which enhanced wound healing and macrophage activity in a rat model.

This review synthesizes recent research on exosomes, highlighting their role as key modulators in regenerative outcomes and suggesting they may offer advantages over stem cell-based therapies in process and regulation.

This review discusses current knowledge on the biological mechanisms of different types of alopecia but reports no new clinical findings; the authors highlight future research directions, especially regarding epidermal stem cells and immune pathways.

This study demonstrated that a mechanical-assisted post-bioprinting strategy significantly increased cell numbers and enhanced regenerative capabilities in hollow hydrogel-based scaffolds for bone defect repair in vivo.

This study found that hydroxysafflor yellow A-rich Carthamus tinctorius extract promoted hair growth and gene expression linked to hair proliferation in both cell cultures and mouse models.