10 citations,
July 1994 in “Journal of Dermatological Science” Cyclosporin extends hair growth in mice, but high-dose corticosteroids block this effect.
9 citations,
December 2022 in “Phytomedicine” More high-quality research is needed to recommend flavonoids and saponins for clinical use.
9 citations,
July 2022 in “Journal of Biological Chemistry” WWP2 is crucial for tooth development in mice.
9 citations,
February 2022 in “Genes” Women with PCOS have more Bifidobacterium in their gut compared to those without PCOS.
9 citations,
August 2021 in “Journal of clinical medicine” Pili torti is a rare condition where hair is twisted and breaks easily, often linked to genetic disorders or other health issues.
9 citations,
July 2021 in “Essays in Biochemistry” Sex hormones may influence COVID-19 severity, with males at higher risk, and certain hormone therapies could potentially treat the virus.
9 citations,
May 2021 in “Frontiers in Cell and Developmental Biology” DNA methylation changes in women with PCOS could be used as disease markers and suggest new treatment targets.
9 citations,
March 2018 in “International journal of molecular sciences” Allopregnanolone changes gene expression in glioblastoma cells.
9 citations,
July 2016 in “Genes” Genetic variants in PDE6H and LPAR6 cause vision impairment and hair loss in two Pakistani brothers.
7 citations,
June 2022 in “Frontiers in Veterinary Science” Researchers found genes linked to hair growth cycles in Inner Mongolia cashmere goats, which could help understand and treat hair loss.
7 citations,
June 2022 in “Frontiers in Medicine” ADSC-derived extracellular vesicles show promise for skin and hair regeneration and wound healing.
7 citations,
March 2022 in “International Journal of Molecular Sciences” The study investigates the role of Fibroblast Growth Factor 21 (FGF21) in suppressing inflammatory reactions induced by Cutibacterium acnes (C. acnes) in skin. Using both mouse models (n = 5-6 mice/group) and cultured keratinocytes, the researchers found that FGF21 significantly reduces the expression of pro-inflammatory cytokines (IL-1β, IL-6, IL-8, and TNF-α) and inhibits the NF-κB/MAPK signaling pathways. FGF21 also decreases TLR2 activity, which is crucial in the inflammatory response to C. acnes. These findings suggest that FGF21 has potential therapeutic value in treating C. acnes-induced skin inflammation.
7 citations,
February 2022 in “International Journal of Pharmaceutics” Safflower oil nanoparticles can deliver hFGF10 to hair follicles, reduce inflammation, and potentially speed up hair growth in conditions causing hair loss.
7 citations,
January 2022 in “Anais Brasileiros de Dermatologia” Skin side effects from cancer treatments can lead to changes in therapy and are common, with nail changes being the most frequent.
6 citations,
April 2023 in “Cosmetics” Exosomes could be effective for improving skin health and treating skin diseases.
6 citations,
September 2022 in “Vaccines” Some people developed alopecia areata after COVID-19 vaccination, but it's not caused by the vaccine and most improved with treatment.
6 citations,
August 2022 in “Science immunology” Foxn1 gene regulation is crucial for thymus development but not for hair growth.
6 citations,
August 2022 in “International Journal of Molecular Sciences” EDA signaling is linked to skin disorders, various cancers, and liver disease.
6 citations,
November 2021 in “Oncology Research and Treatment” Low Vitamin D receptor levels in breast cancer are linked to worse outcomes and more bone metastases, and could be a marker for prognosis.
6 citations,
January 2021 in “Frontiers in Immunology” Certain immune cells worsen post-surgery gut paralysis by activating a specific immune response.
6 citations,
June 2012 in “PloS one” A new mRNA variant of the SCF gene in sheep skin produces a shorter, different protein.
5 citations,
October 2022 in “Phenomics” Your skin is like an ecosystem, with its own community of microbes and substances that interact and affect its health.
5 citations,
July 2022 in “Genes” Increasing EGR1 levels makes hair root cells grow faster.
5 citations,
May 2022 in “Diagnostics” Certain genetic markers can indicate higher or lower risk for systemic lupus erythematosus.
5 citations,
March 2022 in “Frontiers in Cell and Developmental Biology” Colostrum-derived exosomes can promote hair growth and may be a promising treatment for hair loss.
5 citations,
September 2021 in “Frontiers in Cell and Developmental Biology” Dihydrotestosterone treatment on 2D and 3D-cultured skin cells slows down hair growth by affecting certain genes and could be a potential target for hair loss treatment.
4 citations,
June 2023 in “Journal of developmental biology” The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.
4 citations,
May 2023 in “Cells” Baricitinib and its combination with lonafarnib improve fat cell formation in certain genetic disorders.
4 citations,
August 2022 in “Cells” lncRNA2919 slows down rabbit hair growth by stopping cell growth and causing cell death.
4 citations,
June 2022 in “BioMed Research International” Using mesenchymal stem cells or their exosomes is safe for COVID-19 patients and helps improve lung healing and oxygen levels.