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The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

Half of people with Alopecia Areata may see hair regrowth within a year without treatment, but recovery is unpredictable.

Changing how mesenchymal stromal cells are grown can improve their healing abilities.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

The circadian clock affects skin stem cell behavior, impacting aging and cancer risk.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

A protein from certain immune cells is key for new hair growth after skin injury in mice.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Different types of skin cells play specific roles in development, healing, and cancer.

A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

New effective scar treatments are urgently needed due to the current options' limited success.

Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.

Some medicinal plants can help heal wounds and may lead to new treatments.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Silver nanoparticles coated with substances like PEG showed strong antibacterial effects and improved wound healing when used in hydrogels.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.