13 citations
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June 2016 in “Dermatologic Therapy” This study found that minoxidil applied to a damp scalp may increase drug penetration in vitro, potentially improving treatment effectiveness.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study formulated a polyherbal shampoo from plant extracts, finding it showed effective antifungal properties against dandruff-causing agents like Malassezia species while providing protective and conditioning effects on hair cuticles, indicating its potential as a natural alternative for dandruff management.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that a formulated polyherbal shampoo demonstrated effective antifungal properties against dandruff-causing fungi, with smooth, intact hair cuticles after treatment, suggesting it may serve as a safe, natural alternative for managing dandruff.
August 2024 in “Bioimpacts” In this study on mice, a hydro-alcoholic solution containing kopexil significantly enhanced hair growth and increased hair-promoting factors without causing notable liver or kidney toxicity compared to minoxidil.
January 2026 in “Updates in clinical dermatology”
33 citations
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April 1990 in “Dermatologic Clinics” Minoxidil effectively treats hair loss, with better results in women.
May 1987 in “Inpharma (Balgowlah)” Topical minoxidil may slow hair loss but often doesn't lead to satisfactory hair regrowth and requires ongoing treatment.
January 2026 in “RIGGS Journal of Artificial Intelligence and Digital Business” This study analyzed the formulation and stability of pomade containing peppermint oil and minoxidil, determining that a particular formulation with 1% paraffin yielded optimal physical and stability characteristics for promoting hair growth, making it the best choice among the tested options.
September 2024 in “Journal of Skin and Stem Cell” In this study, a combination treatment of microinfusion (MMP®) and topical minoxidil showed a modest increase in hair density in a 28-year-old woman with chronic telogen effluvium, particularly in the parieto-vertex region, suggesting potential benefits but underscoring the need for larger trials to confirm efficacy.
Minoxidil can cause hair growth as a side effect.
March 2024 in “Pakistan Journal of Pharmaceutical Sciences” This study found that minoxidil nanoliposomes led to faster hair growth and better scalp bacteria reduction in mice compared to traditional minoxidil.
April 2016 in “Journal of Investigative Dermatology” This study found that a stimulating cream shampoo enhances the penetration of Minoxidil into hair follicles and scalp in a laboratory setting.
This study reported that a topical hair tonic containing a 7.5% talok leaf and 2% pare leaf extract combination promoted hair growth in female Wistar rats similarly to minoxidil, showing a 64.71% increase in hair growth with no significant difference from minoxidil in statistical analysis.
23 citations
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January 2011 in “International Journal of Immunopathology and Pharmacology” In this small study, topical minoxidil 2% was associated with an increase in normal hair shaft production in patients with Monilethrix without any reported side effects.
November 1981 in “InPharma” Topical minoxidil can help regrow hair.
2 citations
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March 1994 in “Journal of the European Academy of Dermatology and Venereology” This case report describes two female patients with white piedra of the scalp who showed remarkable improvement in hair condition after using 2% miconazole nitrate lotion for 8 weeks.
This study found that minoxidil nanoliposomes led to faster hair growth and reduced scalp bacteria in mice compared to free minoxidil.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This research formulated and evaluated a multipurpose herbal liquid shampoo using plant-based extracts, which showed good cleansing action, medium foaming, and caused no skin irritation, suggesting it to be a safe alternative to synthetic shampoos.
January 2023 in “Revista Eletrônica Acervo Saúde” This integrative literature review found that oral Minoxidil is a favorable alternative for individuals intolerant to topical application, effectively treating various forms of alopecia, though side effects like increased hair growth and minor dermatological reactions are noted.
April 2017 in “Journal of Investigative Dermatology” This study found that pre-treatment with a stimulating cream shampoo significantly increased Minoxidil penetration into hair follicles and the scalp compared to using Minoxidil alone.
July 2015 in “Actas Dermo-Sifiliográficas” A woman experienced excessive hair growth after using a hair loss treatment with minoxidil.
19 citations
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December 1985 in “Journal of The American Academy of Dermatology” Minoxidil can cause scalp comedones and acne.
April 2026 in “International Journal of Drug Delivery Technology” The study developed herbal shampoo formulations using isolated phytoconstituents, such as eugenol, rutin, menthol, and camphor, which demonstrated similar antifungal efficacy to ketoconazole but with improved safety and detergency, offering a promising alternative for managing seborrheic dermatitis.
June 2024 in “BioSCIENCE” This study reviewed the use of microinfusion of microparticles (MMP®) with methotrexate for treating alopecia frontal fibrosante and found it reduced symptoms associated with the condition and improved specific scalp measurements, showing that the technique is safe and well-tolerated.
January 2018 in “Elsevier eBooks” This article reviews the mechanisms and uses of minoxidil for hypertension and androgenetic alopecia, without presenting new clinical findings.
July 2025 in “The Journal of Dermatology” This study reported that 5% topical minoxidil lotion may be beneficial for enhancing hair regrowth in patients with telogen effluvium, although its effectiveness is limited by the self-healing nature of the condition and the small sample size.
January 2025 in “Dermatologic Therapy” This study found that adding low-dose oral minoxidil to standard treatment for lichen planopilaris was safe but did not significantly improve hair density or thickness, although minor hair regrowth was observed in some scarring areas.
This study found no significant difference in hair outcomes between patients using Minoxidil 1 shampoo and a placebo shampoo for alopecia over four months.
1 citations
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May 2007 in “International Journal of Dermatology” Minoxidil, when applied to the scalp, can stimulate hair growth but effects vary, stop if treatment ends, and it may cause side effects like fluid retention.
November 2009 in “Eclética Química” In this study, a potentiometric titration method was developed for determining minoxidil, achieving recoveries of 97.4% to 98.7%, and it showed agreement with a chromatographic procedure at a 90% confidence level.