54 citations,
May 1977 in “The Journal of Pediatrics” Minoxidil helps lower high blood pressure in kids, but can cause fluid retention and hair growth.
53 citations,
March 1987 in “Journal of The American Academy of Dermatology” Minoxidil effectively regrows hair in male pattern baldness.
52 citations,
February 1985 in “Archives of Dermatology” Minoxidil absorbs poorly through skin, with low risk of side effects at 1-2% concentration.
51 citations,
May 2010 in “Journal of Drug Targeting” Transcutol-containing vesicles improve minoxidil's skin penetration and hair growth promotion.
47 citations,
November 1982 in “Journal of Cardiovascular Pharmacology” Nitrendipine and nifedipine effectively block muscle contractions, while papaverine relaxes them and minoxidil needs high amounts to work.
46 citations,
December 1992 in “Journal of Investigative Dermatology” Minoxidil decreases LH expression, while hydralazine has mixed effects on prolyl and lysyl hydroxylase activities.
46 citations,
January 1991 in “Journal of Investigative Dermatology” Minoxidil works in liver and outer hair root sheath for hair growth.
44 citations,
October 1989 in “International Journal of Pharmaceutics” Minoxidil's effectiveness decreases as vehicle evaporates; concentration and thermodynamic activity matter.
43 citations,
July 2018 in “Journal of The European Academy of Dermatology and Venereology” Finasteride and minoxidil mix works better for hair growth than minoxidil alone, with similar safety.
43 citations,
January 1977 in “Toxicology and Applied Pharmacology” Minoxidil is mostly safe, but high doses can cause electrolyte imbalances and heart issues in dogs.
42 citations,
February 2018 in “International Journal of Molecular Sciences” Minoxidil boosts hair growth by triggering growth factor release from specific stem cells.
41 citations,
March 1987 in “Journal of The American Academy of Dermatology” Topical minoxidil effectively treats male pattern baldness and prevents hair loss.
40 citations,
January 2018 in “Pharmaceutics” Eucalyptol and oleic acid in nanoemulsions improve minoxidil delivery to hair follicles, potentially enhancing hair loss treatment.
38 citations,
June 2005 in “Contact Dermatitis” Patient had scalp allergy from minoxidil; test helped identify cause and suggest alternative treatments.
34 citations,
May 2017 in “Lasers in Surgery and Medicine” Combining low-level light therapy and minoxidil 5% is more effective for female hair loss than using either treatment alone.
34 citations,
March 2004 in “Journal of Liposome Research” Minoxidil-loaded liposomes effectively deliver to hair follicles, potentially improving hair growth and treating alopecia.
34 citations,
January 1997 in “Skin Pharmacology and Physiology” Minoxidil affects cell growth in two ways: low doses increase growth, while high doses slow it down and can be toxic.
33 citations,
May 1991 in “British Journal of Pharmacology” Cromakalim relaxes various blood vessels, while minoxidil sulphate is more selective; they likely act on different potassium channels.
32 citations,
January 2019 in “American Journal of Clinical Dermatology” Minoxidil helps treat eyebrow thinning, monilethrix, early hair loss, and shortens chemo-related hair loss.
32 citations,
June 2015 in “Dermatologic Therapy” Finasteride and minoxidil together work best for male hair loss.
32 citations,
January 2007 in “Biological & Pharmaceutical Bulletin” Minoxidil and retinol together help hair grow.
32 citations,
January 1994 in “Skin Pharmacology and Physiology” Minoxidil helps hair growth by activating enzymes in hair follicles.
31 citations,
January 1989 in “Clinical and Experimental Dermatology” The study tested a hair treatment and found it can help grow hair, but won't stop baldness. It's safe and works well, but needs more testing.
30 citations,
September 2003 in “Experimental Dermatology” Minoxidil helps prevent stress-caused hair loss in mice.
28 citations,
April 2008 in “Journal of Inclusion Phenomena and Macrocyclic Chemistry” Minoxidil mixed with β-cyclodextrin improves solubility and gradual release.
28 citations,
January 1989 in “Toxicologic Pathology” Minoxidil may cause heart changes; use caution and monitor patients with heart conditions.
28 citations,
January 2004 in “British Journal of Pharmacology” Minoxidil protects heart and improves recovery.
27 citations,
September 2018 in “Medicines” Oleic acid nanovesicles improve minoxidil absorption in hair follicles for alopecia treatment.
26 citations,
July 2003 in “Journal of Cutaneous Medicine and Surgery” Minoxidil solution safely and effectively treats hair loss.
26 citations,
May 2012 in “Pharmaceutical Development and Technology” PEVs effectively deliver minoxidil through skin.