5 citations
,
September 2017 in “Plastic and Aesthetic Research” This study aimed to assess whether using minoxidil alongside nutritional cyclical supplements could boost hair regrowth without antiandrogens or enzyme blockers, focusing on hair root strengthening. Results are not reported.
1 citations
,
November 2023 in “BMC chemistry” In this study, researchers used computational modeling and virtual screening to identify two FDA-approved drugs, Tadalafil and Finasteride, that may effectively inhibit key proteins involved in melanoma progression, suggesting potential for new therapeutic strategies against aggressive melanoma.
May 2025 in “Clinical Proteomics” In this study, researchers identified three proteins, DEFB1, HGFAC, and CYB5D2, as potential drug targets for alopecia areata, and suggested that the traditional Chinese medicine ingredient cimigenol shows promise in interacting with DEFB1 for potential treatment.
December 2024 in “Frontiers in Pharmacology” In this study, human cell models of hair follicles showed that araliadiol, a plant-derived polyacetylene compound, promotes hair growth through the p38/PPAR-γ signaling pathway, suggesting its potential as a new drug candidate for alopecia treatment.
October 2024 in “International Journal of Molecular Sciences” In this study, Rosa rugosa water extract improved hair length and thickness in a mouse model of DHT-induced alopecia by enhancing the expression of hair growth-promoting factors while inhibiting growth-suppressive proteins, suggesting its potential as a natural therapy for hair loss prevention.
October 2022 in “International Journal of Molecular Sciences” This study found that collagen peptides from Mozambique tilapia significantly promoted hair regrowth and increased the proliferation of hair growth factors in vitro and in vivo, suggesting potential as supplements for hair loss prevention.
20 citations
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October 2024 in “British Journal of Dermatology” In this updated guideline, the British Association of Dermatologists' expert group provided 49 management recommendations for alopecia areata and highlighted future research priorities, aiming to improve care for individuals affected by this condition.
14 citations
,
November 2024 in “Pharmaceuticals” This study found that using spanlastics, a nano, surfactant-based drug delivery system, improved the bioavailability, drug release characteristics, and pharmacokinetic behavior of famotidine, a poorly soluble drug, by enhancing its dissolution and membrane permeation.
9 citations
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April 2018 in “Biology of reproduction” This study concluded that dietary changes alter serum progesterone and estradiol levels in late gestation ewes, likely due to metabolism rather than changes in placental steroid synthesis.
8 citations
,
May 2024 in “ACS Applied Materials & Interfaces” This study found that incorporating PCL-based nanoscaffolds into liver spheroids enhances their viability and liver-specific biofunctionality, suggesting these scaffolds improve the model's potential for preclinical drug screening by increasing sensitivity to acetaminophen toxicity compared to traditional methods.
7 citations
,
August 2023 in “EClinicalMedicine” This study reported that anti-androgens combined with lifestyle modifications were more effective than metformin and lifestyle in reducing hirsutism and certain hormonal measures in women with PCOS, but they were not more effective than a placebo combined with lifestyle changes.
4 citations
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April 2012 in “Asian-australasian Journal of Animal Sciences” This study found that applying deer antler extract to rat skin wounds enhanced hair growth and increased IGF-I expression, suggesting potential use in hair growth products.
3 citations
,
December 2024 in “Stem Cell Reports” In this study, researchers observed that low levels of fucose-binding lectin staining characterize limbal epithelial progenitor cells, which maintain a high proliferative capacity and may be enhanced by inhibiting fucosylation, offering insights for regenerative therapy of the limbal stem cell niche.
3 citations
,
October 2023 in “Cosmetics” This study developed effervescent cleansing tablets containing asiatic-acid-loaded solid lipid microparticles, finding that they provided effective cleansing compared to water and showed good flow properties, pH, and hardness but were unstable at high temperature and humidity.
1 citations
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March 2022 in “Journal of Dermatological Science” This study concluded that overexpressing TERT and BMI1 in cultured human dermal papilla cells extended their lifespan and enhanced their ability to induce hair growth in mice.
July 2025 in “Reproductive Biology and Endocrinology” This study found that early postnatal androgen activity affects the long-term expression of hormone receptors differently in female Wistar rats, influencing neural system programming during development.
September 2008 in “Fertility and Sterility” This study found that pregnancies with gestational diabetes in a Midwestern U.S. cohort demonstrated elevated androgen levels compared to healthy controls, suggesting a common relationship between impaired glucose tolerance and hyperandrogenemia across diverse ethnic backgrounds.
March 2013 in “Molecular & Cellular Toxicology/Molecular & cellular toxicology” In this study, exposure to m-Aminophenol in human keratinocytes altered the expression of thousands of genes involved in inflammation and stress responses, suggesting potential biomarkers for MAP-induced skin toxicity.
63 citations
,
September 1987 in “Journal of Biological Chemistry” Minoxidil slows fibroblast growth and collagen production, potentially treating keloids, hypertrophic scars, and connective tissue disorders.
12 citations
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January 2010 in “PubMed” This article summarizes the MHRA report on finasteride and does not present new clinical findings.
October 2020 in “System Dynamics Review” This study models the pathways of nandrolone and its metabolites in the body and suggests methods to counteract finasteride's role in enabling PED users to cheat drug tests.
130 citations
,
January 2017 in “International journal of nanomedicine” This study found that Na CMC hydrogel loaded with PEG-coated silver nanoparticles demonstrated superior antibacterial and wound-healing efficacy compared to commercial silver sulfadiazine cream in a wound-healing model.
42 citations
,
September 2018 in “Journal of Fungi” This study highlights the challenges in treating Microsporum canis infections due to variable antifungal drug efficacy and potential resistance, emphasizing the need for standardized methods to assess drug susceptibility.
40 citations
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November 2017 in “International journal of nanomedicine” In this study, the researchers reported that chloramphenicol-loaded liposomes, particularly those incorporating deoxycholic acid, enhanced follicular uptake and showed strong antibacterial activity against methicillin-resistant Staphylococcus aureus, offering potential for treating MRSA-infected skin conditions with good skin biocompatibility and minimal toxicity.
31 citations
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October 2020 in “Journal of nanomaterials” This study suggests that silver nanoparticles synthesized using Grewia optiva leaf extract exhibit stronger antibacterial and antioxidant properties than the leaf extract alone.
8 citations
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November 2022 in “Cureus” In this study, patients with mild to moderate scalp seborrheic dermatitis experienced greater improvements in severity scores and quality of life with Lulican™ shampoo compared to Ketoconazole over four weeks, with similar safety profiles but better tolerability and cosmetic acceptability for LulicanTM.
5 citations
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January 2006 in “Journal of obstetrics and gynaecology” Metformin can cause hair loss in some women with PCOS.
3 citations
,
December 2021 in “Journal of medicinal plants” This review discusses the diverse bioactivities and potential applications of Halocnemum strobilaceum but reports no new experimental findings.
2 citations
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January 2016 in “Andrology” This case report study presents two instances of post-finasteride syndrome, highlighting the persistence of sexual adverse effects despite discontinuation of the drug, and underscores the need for increased awareness and understanding of this condition.
April 2026 in “Ankara Üniversitesi Veteriner Fakültesi Dergisi” This study found that Mueller-Hinton Agar performed better than Dermasel Agar for antifungal susceptibility testing of feline dermatophytes, providing reliable susceptibility data for effective antifungal therapy.