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Parkinson's Disease and Skin Disorders: Non-Iatrogenic and Iatrogenic Connections

research Parkinson's disease and skin

28 citations , January 2021 in “Parkinsonism & related disorders (Online)/Parkinsonism & related disorders”

This article reviews skin disorders in Parkinson's disease, highlighting the potential of skin studies and stem cell research to advance understanding and treatment of the neurodegenerative disorder, without presenting new results.

research Drug Delivery System Based On Minoxidil Nanoparticles Promotes Hair Growth In C57BL/6 Mice

28 citations , September 2019 in “International Journal of Nanomedicine”

This study found that minoxidil nanoparticles increased drug delivery to hair follicles and improved hair growth more effectively in mice than conventional minoxidil formulations.

research Efficacy of topical tofacitinib in promoting hair growth in non-scarring alopecia: possible mechanism via VEGF induction

27 citations , September 2017 in “Archives of Dermatological Research”

In this study, topical tofacitinib significantly increased hair regrowth in mice compared to minoxidil or vehicle, potentially due to elevated VEGF levels and reduced inflammation.

research Neuropsychiatric Systemic Lupus Erythematosus Presenting as Bipolar I Disorder With Catatonic Features

26 citations , September 2009 in “Psychosomatics”

This case report highlights the importance of recognizing that neuropsychiatric symptoms in adolescents may signal the onset of systemic lupus erythematosus rather than a primary psychiatric disorder.

research Vertex balding, plasma insulin-like growth factor 1, and insulin-like growth factor binding protein 3

26 citations , June 2000 in “Journal of The American Academy of Dermatology”

This study found that older men with vertex balding had lower levels of IGFBP-3 and higher levels of IGF-1 in their plasma.

research Optimization of menthol-loaded nanocapsules for skin application using the response surface methodology

25 citations , July 2019 in “Journal of drug delivery science and technology”

This study developed lipid-core nanocapsules for encapsulating menthol, improving its solubility and thermal stability, and demonstrated their safety and rapid skin absorption in ex vivo tests, highlighting potential applications for cosmeceuticals.

research Expression of steroidogenic enzymes in human sebaceous glands

25 citations , June 2014 in “Journal of Endocrinology/Journal of endocrinology”

This study found that local androgen biosynthesis and metabolism in human sebaceous glands play a crucial role in sebum synthesis and secretion.

research Guidelines for the Use of Acitretin in Psoriasis

25 citations , July 2013 in “Actas Dermo-Sifiliográficas”

This review discusses consensus guidelines for the use of acitretin in psoriasis, highlighting its ongoing utility in both mono and combination therapies, despite not always being recognized in treatment guidelines.

research Cross-species sensitivity to a novel androgen receptor agonist of potential environmental concern, spironolactone

25 citations , July 2013 in “Environmental Toxicology and Chemistry”

This study found that spironolactone reduced fish fecundity and caused masculinization of females at certain concentrations, while having no effect on Daphnia magna reproduction, underscoring concerns for environmental exposure to vertebrates.

research Critical Role of ATP-P2X7 Axis in UV-Induced Melanogenesis

23 citations , March 2019 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study found that extracellular ATP released from UVB-irradiated keratinocytes promotes melanin production through the P2X7 receptor, indicating a role for ATP-P2X7 signaling in UV-induced melanogenesis.

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