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    Glossary Mineralocorticoid Receptor

    protein that regulates salt and water balance in cells

    The Mineralocorticoid Receptor (MR) is a type of protein found inside cells that binds to mineralocorticoids, such as the hormone aldosterone. This receptor plays a crucial role in regulating the balance of salt and water in the body by influencing kidney function. When activated, it helps control blood pressure and fluid balance, making it important for both everyday health and in conditions like hypertension and heart failure.

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    Research 30 of 408

    1. The Acute Anticonvulsant Effects of Deoxycorticosterone in Developing Rats: Role of Metabolites and Mineralocorticoid‐receptor Responses Epilepsia · 2005 · 13 citations
    2. Polymeric micelle mediated follicular delivery of spironolactone: Targeting the mineralocorticoid receptor to prevent glucocorticoid-induced activation and delayed cutaneous wound healing International Journal of Pharmaceutics · 2021 · 9 citations
    3. Mineralocorticoid Receptor Antagonists—A New Sprinkle of Salt and Youth Journal of Investigative Dermatology · 2016 · 8 citations
    4. Association between Mineralocorticoid Receptor Antagonist and Mortality in SARS-CoV-2 Patients: A Systematic Review and Meta-Analysis Healthcare · 2022 · 10 citations
    5. A novel actor in skin biology: the mineralocorticoid receptor Experimental dermatology · 2015 · 7 citations
    6. Mineralocorticoid Receptor Antagonists Stimulate Human Hair Growth ex vivo Skin Pharmacology and Physiology · 2019 · 1 citations
    7. Pharmacovigilance profiles of three generations of mineralocorticoid receptor antagonists and network toxicology analysis Frontiers in Medicine · 2026
    8. Targeted Skin Overexpression of the Mineralocorticoid Receptor in Mice Causes Epidermal Atrophy, Premature Skin Barrier Formation, Eye Abnormalities, and Alopecia American Journal of Pathology · 2007 · 67 citations
    9. The mineralocorticoid receptor as a novel player in skin biology: beyond the renal horizon? Experimental Dermatology · 2009 · 40 citations
    10. The mineralocorticoid receptor plays a transient role in mouse skin development Experimental Dermatology · 2015 · 12 citations
    11. The myeloid mineralocorticoid receptor regulates dermal angiogenesis and inflammation in glucocorticoid‐induced impaired wound healing British Journal of Pharmacology · 2022 · 9 citations
    12. Faculty Opinions recommendation of Targeted skin overexpression of the mineralocorticoid receptor in mice causes epidermal atrophy, premature skin barrier formation, eye abnormalities, and alopecia. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2007
    13. Cutaneous Wound Healing in Diabetic Mice Is Improved by Topical Mineralocorticoid Receptor Blockade Journal of Investigative Dermatology · 2019 · 66 citations
    14. Glucocorticoid and Sex Hormone Receptors: Clinical Implications and Therapeutic Relevance Dermatologic Clinics · 2007 · 4 citations
    15. Roles of steroid receptors in the lung and COVID-19 Essays in Biochemistry · 2021 · 9 citations
    16. SARS-CoV-2 Spike Protein S1-Mediated Endothelial Injury and Pro-Inflammatory State Is Amplified by Dihydrotestosterone and Prevented by Mineralocorticoid Antagonism Viruses · 2021 · 50 citations
    17. The Glucocorticoid Resistance Syndrome. Two Cases of a Novel Pathogenic Variant in the Glucocorticoid Receptor Gene JCEM case reports · 2023
    18. Chrousos syndrome: from molecular pathogenesis to therapeutic management European Journal of Clinical Investigation · 2015 · 47 citations
    19. Atualização em Coriorretinopatia Serosa Central e-Oftalmo CBO Revista Digital de Oftalmologia · 2016
    20. Disruption of androgen metabolism, regulation and effects : involvement of steroidogenic enzymes edoc (University of Basel) · 2014
    21. Spironolactone Practical Diabetes · 2024
    22. Oral medications for central serous chorioretinopathy: a literature review Eye · 2019 · 14 citations
    23. Steroid Hormones Elsevier eBooks · 2016 · 3 citations
    24. Case report: A pregnant woman accidental treated with spironolactone in mid-gestation Frontiers in Pharmacology · 2024 · 1 citations
    25. Pharmacology of different progestogens: the special case of drospirenone Climacteric · 2005 · 104 citations
    26. Association of androgenetic alopecia and hypertension. PubMed · 2007 · 34 citations
    27. Current Therapeutic Approaches to Chronic Central Serous Chorioretinopathy Türk oftalmoloji dergisi · 2019 · 13 citations
    28. Profile of the progesterone derivative chlormadinone acetate — Pharmocodynamic properties and therapeutic applications Contraception · 2009 · 33 citations
    29. Abiraterone and spironolactone in prostate cancer: a combination to avoid Acta Clinica Belgica · 2018 · 9 citations
    30. Primary Generalized Glucocorticoid Resistance or Chrousos Syndrome: Allostasis Through a Mutated Glucocorticoid Receptor Springer eBooks · 2016