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The glucocorticoid receptor helps protect skin from tumors and other issues.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Spironolactone improved blood vessel function and cholesterol levels in non-obese women with PCOS.

Spironolactone might lower the chance of getting rosacea.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.

Some skin conditions may indicate metabolic syndrome, which could help with early detection and management of related health issues.

Sulforaphane may help with hair growth by breaking down a hormone that causes hair loss.

New insights into the causes and treatments for the autoimmune hair loss condition Alopecia areata have been made.

The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.

The androgen receptor's shape-changing ability helps it function but can lead to cancer treatment resistance.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Hormones are crucial for regulating body functions and imbalances can lead to health issues.

Excessive hair growth can be assessed by history, exam, and blood tests, and treated with medication like dexamethasone, birth control pills, and spironolactone.

Finasteride reduces alcohol withdrawal severity in male mice but increases it in female mice.

Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.

Spironolactone may cause sexual pain and arousal issues in women, which can improve after stopping the drug and using hormone cream.

Higher dihydrotestosterone may be linked to more inflammation in COVID-19 patients with low testosterone.

The testes produce important hormones like testosterone and others that play key roles in male body functions.

Mice with a virus similar to COVID-19 had skin damage, but a special treatment helped repair it.

Alopecia X in dogs is a cosmetic issue, not a hormonal disorder, and harmful treatments should be avoided.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.

Spironolactone is effective for acne, hidradenitis suppurativa, female hair loss, and hirsutism but is underused in dermatology.

Overexpression of a specific receptor in mice skin causes skin thinning, early skin barrier formation, eye issues, and hair loss.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.