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Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.

Most dermatologic medications are safe during pregnancy and breastfeeding, but some should be avoided due to potential risks.

Genetic screening is crucial for accurately diagnosing APS-1 due to its varied symptoms.

Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

Hidradenitis suppurativa may be related to hormones and patients often have metabolic disorders; more research is needed to understand this connection.

The conclusion is that accurately identifying the cause of high androgen levels in women with PCOS is crucial and requires specific tests.

APS-1 in Italy shows diverse AIRE mutations and various autoimmune issues.

Early adrenal gland maturation in young children can be normal, but other serious conditions should be ruled out first.

Men with common hair loss may have a higher risk of heart disease and diabetes, and should be checked for these conditions.

Nonclassic congenital adrenal hyperplasia is a genetic disorder causing hormone imbalances, affecting fertility and requiring personalized treatment.

Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.

Skin diseases linked to insulin resistance should be managed to prevent diabetes and reduce heart disease risk.

Excessive hair growth in women can be harmless or signal serious health issues, and treatment often includes medication and hair removal, with noticeable results after 3-6 months.

Male tissue has more cell death than female tissue after ischemia, and some neurosteroids only protect female cells.

Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.

Licorice has many traditional health benefits, but more research is needed to fully support these claims.

A man with hypoparathyroidism had other health issues that led to a diagnosis of a rare autoimmune disorder, APS-1.

Identifying nonclassic congenital adrenal hyperplasia and carriers of CYP21 mutations is challenging, and genetic counseling is recommended due to their prevalence.

The chapter explains the causes of excessive hair growth and masculinization in women and how to measure hormone levels related to these conditions.

PCOS treatment focuses on lifestyle changes and specific medications to manage symptoms and complications.

Hyperandrogenism increases heart disease risk in premenopausal women, but this risk is linked to obesity in postmenopausal women.

Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.

The document concludes that managing skin conditions during pregnancy is important and requires specialized care.

Hair loss linked to prostate enlargement; stress and family history important factors.

Hair loss may increase heart disease risk.

Men with early hair loss may have higher insulin resistance and should be checked for related health issues.

Non-classical 21 hydroxylase deficiency is an underdiagnosed cause of female hair loss and polycystic ovarian syndrome.

Long-term use of azole antifungals can cause hair loss, hormonal imbalances, and severe skin reactions.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.