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    Glossary Mineralocorticoid Receptor

    protein that regulates salt and water balance in cells

    The Mineralocorticoid Receptor (MR) is a type of protein found inside cells that binds to mineralocorticoids, such as the hormone aldosterone. This receptor plays a crucial role in regulating the balance of salt and water in the body by influencing kidney function. When activated, it helps control blood pressure and fluid balance, making it important for both everyday health and in conditions like hypertension and heart failure.

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    Research 30 of 470

    1. Association between Mineralocorticoid Receptor Antagonist and Mortality in SARS-CoV-2 Patients: A Systematic Review and Meta-Analysis Healthcare · 2022 · 10 citations
    2. Mineralocorticoid Receptor Antagonists—A New Sprinkle of Salt and Youth Journal of Investigative Dermatology · 2016 · 8 citations
    3. Mineralocorticoid Receptor Antagonists Stimulate Human Hair Growth ex vivo Skin Pharmacology and Physiology · 2019 · 1 citations
    4. Pharmacovigilance profiles of three generations of mineralocorticoid receptor antagonists and network toxicology analysis Frontiers in Medicine · 2026
    5. SARS-CoV-2 Spike Protein S1-Mediated Endothelial Injury and Pro-Inflammatory State Is Amplified by Dihydrotestosterone and Prevented by Mineralocorticoid Antagonism Viruses · 2021 · 50 citations
    6. Polymeric micelle mediated follicular delivery of spironolactone: Targeting the mineralocorticoid receptor to prevent glucocorticoid-induced activation and delayed cutaneous wound healing International Journal of Pharmaceutics · 2021 · 9 citations
    7. A novel actor in skin biology: the mineralocorticoid receptor Experimental dermatology · 2015 · 7 citations
    8. Association of androgenetic alopecia and hypertension. PubMed · 2007 · 34 citations
    9. Oral medications for central serous chorioretinopathy: a literature review Eye · 2019 · 14 citations
    10. Current Therapeutic Approaches to Chronic Central Serous Chorioretinopathy Türk oftalmoloji dergisi · 2019 · 13 citations
    11. Steroid Hormones Elsevier eBooks · 2016 · 3 citations
    12. Case report: A pregnant woman accidental treated with spironolactone in mid-gestation Frontiers in Pharmacology · 2024 · 1 citations
    13. Spironolactone Practical Diabetes · 2024
    14. Atualização em Coriorretinopatia Serosa Central e-Oftalmo CBO Revista Digital de Oftalmologia · 2016
    15. The myeloid mineralocorticoid receptor regulates dermal angiogenesis and inflammation in glucocorticoid‐induced impaired wound healing British Journal of Pharmacology · 2022 · 9 citations
    16. Targeted Skin Overexpression of the Mineralocorticoid Receptor in Mice Causes Epidermal Atrophy, Premature Skin Barrier Formation, Eye Abnormalities, and Alopecia American Journal of Pathology · 2007 · 67 citations
    17. The Acute Anticonvulsant Effects of Deoxycorticosterone in Developing Rats: Role of Metabolites and Mineralocorticoid‐receptor Responses Epilepsia · 2005 · 13 citations
    18. The mineralocorticoid receptor as a novel player in skin biology: beyond the renal horizon? Experimental Dermatology · 2009 · 40 citations
    19. Glucocorticoid and Sex Hormone Receptors: Clinical Implications and Therapeutic Relevance Dermatologic Clinics · 2007 · 4 citations
    20. Abiraterone and spironolactone in prostate cancer: a combination to avoid Acta Clinica Belgica · 2018 · 9 citations
    21. Corticotropin releasing factor-1 receptor antagonism associated with favorable outcomes of male reproductive health biochemical parameters Frontiers in Endocrinology · 2023
    22. Recent discoveries and developments of androgen receptor based therapy for prostate cancer MedChemComm · 2015 · 17 citations
    23. Androgen antagonists in androgen target tissues Pharmacology & Therapeutics · 1984 · 27 citations
    24. Androgen receptor modulators: a review of recent patents and reports (2012-2018) Expert Opinion on Therapeutic Patents · 2019 · 23 citations
    25. Roles of steroid receptors in the lung and COVID-19 Essays in Biochemistry · 2021 · 9 citations
    26. Treatment of androgen excess in females: Yesterday, today and tomorrow Gynecological Endocrinology · 1997 · 9 citations
    27. Improvement of female pattern hair loss with bicalutamide: a time-dependent process JAAD International · 2025
    28. Restricted effects of androgens on glucocorticoid signaling in the mouse prefrontal cortex and midbrain Frontiers in Endocrinology · 2024 · 3 citations
    29. Pharmacological Approaches to Controlling Cardiometabolic Risk in Women with PCOS International Journal of Molecular Sciences · 2020 · 26 citations
    30. Long-term Prophylaxis with Androgens in the management of Hereditary Angioedema (HAE) in emerging countries Orphanet Journal of Rare Diseases · 2022