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Blocking CRF1 receptors improved male hormone levels and reduced testicular tumor size in men with a specific adrenal condition.

DHEA affects various tissues by interacting with multiple receptors and can be converted into sex hormones.

Spironolactone improved cognitive performance and early sleep quality but not manic symptoms, appetite, or body weight in bipolar disorder when added to sodium valproate.

Diagnosing and managing Glucocorticoid Resistance Syndrome is complex due to genetic differences and varied symptoms.

Blocking LFA-1 prevents hair loss in mice.

The androgen receptor's shape-changing ability helps it function but can lead to cancer treatment resistance.

Some antiandrogens may lower testosterone better than others, but it's unclear which is best for feminization in transgender women; more research is needed.

Natural products may help treat skin inflammation from abnormal adrenal hormones.

Non-classical 21 hydroxylase deficiency is an underdiagnosed cause of female hair loss and polycystic ovarian syndrome.

Oral estradiol works for many transgender women but needs personalized dosing and monitoring.

Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.

Five preservatives may disrupt hormone function and need more health and environmental risk assessment.

Metabolic syndrome is more common in people with early-onset androgenic alopecia.

Ashwagandha may improve hormone levels and reduce hair loss in non-classical adrenal hyperplasia.

Special particles from umbilical cord stem cells help heal skin wounds in diabetic mice by preventing certain immune cell death.

Testosterone and its metabolites affect brain functions and could help treat neurological disorders.

Hormonal therapies effectively treat acne and improve quality of life.

Long-term use of androgens can help manage Hereditary Angioedema (HAE) but may cause serious side effects, so alternative treatments with fewer side effects are being considered.

Congenital Adrenal Hyperplasia is a rare inherited disease causing hormone imbalances, affecting growth, fertility, and heart health, diagnosed through blood tests and treated with medication and lifestyle changes.

Ferulic acid may help control menstrual cycle-related epilepsy by affecting female hormones.

Mutations in the Vitamin D receptor gene can cause hair loss similar to mutations in the Hairless gene.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Calcineurin inhibitors, used in kidney transplants, can cause a wide range of side effects including kidney damage and other health issues.

Long-term use of azole antifungals can cause hair loss, hormonal imbalances, and severe skin reactions.

No single treatment is clearly effective for central serous chorioretinopathy.

Oral contraceptives provide various health benefits beyond birth control, including managing menstrual issues, skin conditions, pain, and reducing the risk of certain cancers.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

New insights into the causes and treatments for the autoimmune hair loss condition Alopecia areata have been made.

Women may need different blood pressure guidelines than men for heart disease prevention.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.