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A very low-calorie ketogenic diet is effective for quick weight loss and improving health in obese patients, with careful management of side effects and maintenance.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

Fatty acid transport protein 4 is essential for skin and hair development.

Skin fat helps with body temperature control and has other active roles in health.

Low-oxygen conditions and ECM degradation products increase the healing abilities of perivascular stem cells.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Mouflon rams mature gradually with changes in body, horns, and hormones linked to age and seasons, reaching full sexual maturity well after puberty.

Minoxidil helps hair growth by activating the β-catenin pathway.

Blocking β-catenin in skin cells improves hair growth during wound healing.

The document concludes that diagnosing and treating Human African Trypanosomiasis is challenging, but new treatments like fexinidazole are promising.

TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.

Green tea may help with health issues like cancer, heart disease, and weight loss due to its high catechin content.

Mutant mice help researchers understand hair growth and related genetic factors.

Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.

Children with loose anagen hair have easily pluckable hair due to root sheath problems, and it might improve without treatment.

Hair mineral analysis might help diagnose diseases early, but standard methods are needed.

Mouse skin can produce and process serotonin, with variations depending on hair cycle, body location, and mouse strain.

Minoxidil boosts hair growth by activating PGHS-1.

A weight loss program with a special fast helped patients lose an average of 41-47 pounds and improved their health, but maintaining the weight loss was challenging.

Excessive selenium from a supplement caused toxicity but patients recovered with care.

Acne treatment varies, with topical and systemic therapies effective, and more research needed on treatment order and long-term effects.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

Methotrexate is a key, cost-effective drug for skin conditions, but requires careful monitoring for side effects.

Zinc deficiency in children can cause skin issues and can be serious if not diagnosed and treated properly.

Toxic epidermal necrolysis is a severe skin condition often caused by drugs, with complex treatment and a high risk of death, but survivors usually heal without scars.

Most dermatologic medications are safe during pregnancy and breastfeeding, but some should be avoided due to potential risks.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.