January 2011 in “Padua Research Archive (University of Padua)” This study suggests that human skin locally synthesizes active sex steroid hormones, impacting inflammation, cell behavior, and wound healing, with potential implications for therapies in aging and impaired wound recovery.
March 2009 in “Encyclopedia of Life Sciences” This article reviews keratin disorders and highlights recent progress in therapeutic approaches, including a clinical trial for pachyonychia congenita using siRNA, but reports no new clinical findings.
January 2009 in “한국피부장벽학회지” This study reports that in mice, CaR plays a critical role in sensing the epidermal Ca2+ gradient, influencing keratinocyte differentiation, and affecting epidermal development.
June 2008 in “Dermatologic Surgery” This review discusses the effects of hydrogen peroxide in hair restoration surgery and other medical specialties, finding both potential benefits and risks, but reports no conclusive data for its optimal use in hair transplants.
This dissertation reported that the loss of Ovol2 impairs hair follicle regeneration and wound repair in mice, highlighting its role in regulating directional migration of epithelial cells.
309 citations
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October 2007 in “Biomaterials” This study found that a biomaterial gel made from human hair keratins facilitated nerve regeneration in an animal model, potentially matching the effectiveness of traditional autografts.
166 citations
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April 2019 in “International Journal of Molecular Sciences” The researchers reported that they predicted associations between certain components of MSC-conditioned medium and its ability to stimulate cell migration in vitro, identifying factors affecting its biological activity.
61 citations
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June 2014 in “Scientific Reports” This study found that overexpression of Wnt1a in bone marrow mesenchymal stem cells enhanced mouse hair follicle regeneration and promoted hair cycling.
55 citations
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June 2012 in “Steroids” This study found that testosterone modulates vascular cell behavior through direct actions that do not rely on its conversion to estradiol.
51 citations
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April 2013 in “Journal of Investigative Dermatology” Hair follicle stem cells rely on nearby blood vessels for their maintenance and function.
48 citations
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April 2021 in “Pharmaceuticals” This study found that curcumin encapsulated in liposomes enhanced photodynamic therapy's effectiveness against skin cancer cells while reducing toxicity to normal human keratinocytes.
35 citations
,
March 2010 in “Journal of Dermatological Science” Ebastine may help regrow hair in alopecia areata patients.
13 citations
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January 2021 in “Journal of Cellular and Molecular Medicine” This review discusses the roles and mechanisms of thymosin β4 in hair follicle growth and development but reports no new experimental findings; the authors emphasize the need for further research on its molecular pathways.
13 citations
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July 2019 in “PLoS ONE” This study found that deleting podoplanin in mouse keratinocytes promoted hair follicle growth during regeneration, suggesting it may regulate hair cycling pathways that could aid in treating hair loss conditions.
11 citations
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October 2007 in “Journal of Investigative Dermatology” Mutations in the Sgk3 gene cause fuzzy hair in mice.
9 citations
,
July 2022 in “EMBO molecular medicine” This study found that targeting IL-6, IL-1, and CCR6 signaling pathways may effectively reduce irradiation-induced alopecia and dermatitis in radiotherapy patients.
5 citations
,
June 2024 in “Pharmacological Research” This study identified neuropilin-1 as the receptor for FOL-026 and showed that it stimulates angiogenesis and cell growth, suggesting potential for vascular repair and enhanced angiogenesis therapies.
5 citations
,
March 2012 in “Clinical and Experimental Dermatology” A woman experienced temporary hair loss after taking albendazole, which resolved on its own within 3 months.
3 citations
,
February 2018 in “Aesthetic plastic surgery” This study found that the locked cheek lift technique effectively corrects cheek gravitational migration and reduces the lid cheek distance with minimal complications, maintaining results for over a year.
2 citations
,
November 2025 in “Cells” This review presents evidence supporting the potential of adipose-derived stem cell secretome as a promising cell-free therapy for skin repair, emphasizing its application in wound healing, alopecia, skin rejuvenation, and inflammatory skin diseases.
1 citations
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February 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that electrospinning membranes with smaller fiber diameters significantly improved skin wound healing by promoting cell proliferation and encouraging reparative macrophage transformation.
1 citations
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July 2019 in “Clinical Rheumatology” Leflunomide is more likely to help treat alopecia areata than cause it.
January 2026 in “Inflammation and Regeneration” This review highlights that two-photon excitation microscopy is a valuable tool for visualizing live skin structures and immune responses at high resolution, though its clinical use is hindered by safety and cost issues.
December 2025 in “Molecules” This study found that the 15-PGDH inhibitor DPP improved endothelial function in hair-related cells exposed to DHT by reducing oxidative stress and enhancing angiogenic capacity.
November 2025 in “Journal of Investigative Dermatology” Certain immune cells in atopic dermatitis skin could be targeted for treatment.
November 2025 in “Journal of Investigative Dermatology” CBD can help hair grow by supporting scalp health and reducing inflammation.
March 2025 in “International Journal of Dermatology” In this case study, a 20-year-old man experienced progressive hair loss starting as a localized patch on the vertex of his scalp, eventually spreading in a curvilinear pattern to the sides and back.
November 2024 in “Journal of Investigative Dermatology” Androgens reduce hair growth by affecting cell differentiation and blood vessel formation.
December 2023 in “Chiwi'saeng'gwa haghoeji” Hair keratin protein might help heal mouth wounds faster.
November 2023 in “Periodontology 2000” This narrative review examines the technological advancements and clinical applications of liquid injectable platelet-rich fibrin (i-PRF), discussing its use across regenerative periodontology, sports medicine, and more, as well as its potential as a drug delivery system.