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Cells with active Wnt signaling are less likely to turn into cancer when exposed to a cancer-causing gene.

Anti-androgens can help manage some PCOS symptoms better than metformin but are not more effective than placebos or birth control pills for other symptoms.

Schizophrenia risk genes may affect early brain development, contributing to the disease.

No single treatment is clearly effective for central serous chorioretinopathy.

Oral isotretinoin may slightly improve acne but increases the risk of side effects like dry lips and skin; more research is needed to understand its full risks and benefits.

Hormone therapy increases the risk of heart-related issues in transgender women and may affect heart health in transgender men.

Fluorescence can effectively measure acne treatment progress.

Certain skin conditions in women are linked to higher risks of metabolic syndrome and type 2 diabetes due to hormone imbalances.

Povidone iodine reduced skin bacteria more than chlorhexidine gluconate, but neither met FDA reduction standards.

MicroRNAs could be key biomarkers and therapeutic targets for PCOS.

The conclusion is that obesity should be managed with a slow, balanced approach to diet and exercise, with medication and surgery as additional options, and education and access to care are important.

Vitamin D is important for skin health and can help treat psoriasis, atopic dermatitis, and vitiligo.

Hormonal male contraception is effective and could be market-ready, but more research is needed to ensure safety for all ethnic groups.

Colchicine might help treat different skin diseases, but more research is needed to confirm its effectiveness and safe dosage.

Testosterone can help premenopausal and postmenopausal women with low sexual desire, but its long-term safety is unclear and it's not widely approved for this use.

Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.

Nanofat shows promise for facial rejuvenation and treating skin issues but needs more research for long-term safety.

Soy protein with isoflavones reduces wrinkles and improves skin hydration in postmenopausal women.

Obesity can worsen wound healing by negatively affecting the function of stem cells in fat tissue.

Hormone therapy improves mental well-being in transgender individuals but requires ongoing health monitoring.

Genes and epigenetic changes are important in the development of Polycystic Ovary Syndrome.

Genetic risk for PCOS can affect children's growth, metabolism, and development from early life into adulthood.

Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.

More research is needed to understand how testosterone is maintained in adult males.

Neuropathic pruritus is a commonly overlooked and wrongly diagnosed type of chronic itching that is hard to treat.

Efficient delivery systems are needed for the clinical use of CRISPR-Cas9 gene editing.

Androgens, male hormones, affect physical and mental functions, with a decrease leading to health issues like muscle loss, bone disease, and depression, and more research is needed on long-term effects and treatments.

Many patients with cutaneous lupus erythematosus experience hair loss and nail problems, which are important for diagnosis and treatment.

Male hormones worsen kidney transplant damage, but blocking them helps.

Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.