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    Glossary Microvesicles

    Microvesicles are small membrane-bound particles released from the surface of cells, typically ranging from 100 to 1000 nanometers in diameter. They play a significant role in intercellular communication and can carry proteins, lipids, and RNA, influencing various biological processes, including inflammation and cell signaling. In the context of hair loss, microvesicles may be involved in the regulation of hair follicle biology and the pathophysiology of conditions such as androgenetic alopecia, making them a potential target for therapeutic interventions. Their distinguishing characteristic is their origin from the outward budding of the plasma membrane, differentiating them from exosomes, which are formed within endosomes.

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    1. 174 Dermis-hair follicle communication: Extracellular microvesicles signaling for hair regeneration Journal of Investigative Dermatology · 2020
    2. Extracellular Vesicles for Regenerative Medicine Applications Applied Sciences · 2022 · 14 citations
    3. Developmental characteristics of cutaneous telocytes in late embryos of the silky fowl European Journal of Histochemistry · 2024 · 1 citations
    4. Ozone and procaine increase secretion of platelet-derived factors in platelet-rich plasma European journal of histochemistry · 2023 · 1 citations
    5. Bio-Nanovesicle-Based Approaches for Hair and Skin Regeneration: An Updated Concise Review Cells · 2026
    6. The Role of Extracellular Vesicles in the Development and Treatment of Psoriasis: Narrative Review Pharmaceutics · 2024
    7. Prospect of Stem Cell Conditioned Medium in Regenerative Medicine BioMed Research International · 2014 · 298 citations
    8. Exosomes for repair, regeneration and rejuvenation Expert Opinion on Biological Therapy · 2015 · 135 citations
    9. Extracellular vesicles derived from MSCs activates dermal papilla cell in vitro and promotes hair follicle conversion from telogen to anagen in mice Scientific Reports · 2017 · 113 citations
    10. Extracellular vesicle-based drug overview: research landscape, quality control and nonclinical evaluation strategies Signal Transduction and Targeted Therapy · 2025 · 77 citations
    11. The Role of Extracellular Vesicles in Cutaneous Remodeling and Hair Follicle Dynamics International Journal of Molecular Sciences · 2019 · 38 citations
    12. Promoting axonal regeneration through exosomes: An update of recent findings on exosomal PTEN and mTOR modifiers Brain Research Bulletin · 2018 · 14 citations
    13. Hair shaft miRNA‐221 levels as a new tumor marker of malignant melanoma Journal of dermatology · 2014 · 7 citations
    14. Concentrated Conditioned Medium-Loaded Silk Nanofiber Hydrogels with Sustained Release of Bioactive Factors To Improve Skin Regeneration ACS Applied Bio Materials · 2019 · 5 citations
    15. Mesenchymal Stromal Cell Secretome: Influencing Therapeutic Potential by Cellular Pre-conditioning Frontiers in Immunology · 2018 · 320 citations
    16. Biomaterials Functionalized with MSC Secreted Extracellular Vesicles and Soluble Factors for Tissue Regeneration Advanced functional materials · 2020 · 220 citations
    17. Fibrous scaffolds potentiate the paracrine function of mesenchymal stem cells: A new dimension in cell-material interaction Biomaterials · 2017 · 182 citations
    18. Telocytes in human skin – are they involved in skin regeneration? Journal of Cellular and Molecular Medicine · 2012 · 160 citations
    19. Linking diet to acne metabolomics, inflammation, and comedogenesis: an update Clinical, Cosmetic and Investigational Dermatology · 2015 · 138 citations
    20. Regulation of hair follicle development by exosomes derived from dermal papilla cells Biochemical and Biophysical Research Communications · 2018 · 87 citations
    21. Exosomes and Their Bioengineering Strategies in the Cutaneous Wound Healing and Related Complications: Current Knowledge and Future Perspectives International Journal of Biological Sciences · 2023 · 72 citations
    22. Electrospun Nanofibers for Improved Angiogenesis: Promises for Tissue Engineering Applications Nanomaterials · 2020 · 70 citations
    23. Adipose-derived cellular and cell-derived regenerative therapies in dermatology and aesthetic rejuvenation Ageing Research Reviews · 2019 · 60 citations
    24. Stem Cell-Based Tissue Engineering for the Treatment of Burn Wounds: A Systematic Review of Preclinical Studies Stem Cell Reviews and Reports · 2022 · 30 citations
    25. Dental derived stem cell conditioned media for hair growth stimulation PLOS ONE · 2019 · 15 citations
    26. Exosomes as a novel pathway for regulating development and diseases of the skin (Review) Biomedical Reports · 2018 · 15 citations
    27. Platelet-Therapeutics to Improve Tissue Regeneration and Wound Healing—Physiological Background and Methods of Preparation Biomedicines · 2021 · 14 citations
    28. A Novel Secretory Vesicle from Deer Antlerogenic Mesenchymal Stem Cell-Conditioned Media (DaMSC-CM) Promotes Tissue Regeneration Stem Cells International · 2018 · 9 citations
    29. Biomaterials and Stem Cells: Promising Tools in Tissue Engineering and Biomedical Applications InTech eBooks · 2018 · 7 citations
    30. Equine Hoof Stem Progenitor Cells (HPC) CD29 + /Nestin + /K15 + – a Novel Dermal/epidermal Stem Cell Population With a Potential Critical Role for Laminitis Treatment Stem Cell Reviews and Reports · 2021 · 6 citations