89 citations
,
March 2001 in “Endocrine practice” This article provides diagnosis and treatment guidelines for hyperandrogenic disorders in women but reports no new clinical results; it offers a summary of accepted scientific information and suggestions for clinical practice.
39 citations
,
November 2007 in “Journal of Histochemistry & Cytochemistry” This study found that in neonatal mice, the absence of the NG2 proteoglycan leads to reduced epidermal thickness and delayed subcutis thickening due to impaired proliferation and adipocyte deficiencies.
7 citations
,
October 2024 in “Livers” This review highlights the connection between sex hormones and metabolic dysfunction, emphasizing how conditions like male hypogonadism and female hyperandrogenism can increase the risk and severity of hepatic steatosis, which often progresses alongside metabolic syndrome and elevates mortality risks.
6 citations
,
January 2022 in “Journal of Investigative Dermatology” This study found that androgen receptor signaling is linked to blood vessel regression in the dermal papilla of balding scalp, contributing to hair follicle miniaturization in androgenetic alopecia.
1 citations
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January 2017 in “Current Dermatology Reports” This review discusses how hair and nail manifestations can indicate systemic diseases, emphasizing the importance of these appendageal clues in physical diagnosis, but reports no new findings.
In this study, nearly two-thirds of Saudi adults reported experiencing hair loss following COVID-19 infection or vaccination, with female sex and nutritional deficiencies identified as significant correlates for this condition.
February 2024 in “Medicina-lithuania” This narrative review explores how obesity, related diseases, and bariatric surgery can impact hair health and the hair development cycle, highlighting potential effects such as hair thinning and telogen effluvium.
December 2021 in “Indian Journal of Dermatology, Venereology and Leprology” In this study, androgenetic alopecia patients exhibited more nailfold capillary abnormalities, suggesting a potential link between microcirculation issues and the condition.
April 2026 in “Journal of Clinical Medicine” This review summarizes recent research into the effects of GLP-1 receptor agonists on skin processes, noting potential benefits for wound healing but also potential cosmetic concerns like facial fat loss and decreased collagen, highlighting the need for more clinical studies to clarify their dermatological impact.
35 citations
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December 2020 in “International Journal of Molecular Sciences” This review examines the mixed evidence on mast cells as regulators of skin fibrosis and highlights existing gaps in the scientific understanding, reporting no new experimental results.
24 citations
,
November 2015 in “Frontiers in Genetics” This review discusses the development and potential therapeutic effects of nitroxide small molecule agents for age-related macular degeneration and cardiovascular disease, but reports no new clinical results.
23 citations
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January 2016 in “International Journal of Trichology” This study found that women with female pattern hair loss had significantly lower serum Vitamin D3 levels compared to healthy controls.
2 citations
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November 2017 in “Gynecological Endocrinology” This study found that serum myo-inositol oxygenase levels do not differ between women with polycystic ovary syndrome and healthy controls, suggesting that MI deficiency in PCOS is not due to MIOX levels.
January 2024 in “Wiadomości Lekarskie” In this study, researchers analyzed the clinical phenotype and primary pathogenic links in patients who survive the acute phase of a critical illness and rely on prolonged intensive care, finding that these patients show persistent inflammation, nutritional deficiencies, and other chronic complications over time.
21 citations
,
March 2023 in “Journal of Crohn s and Colitis” This study suggests that microvascular damage and platelet deregulation may persist in ulcerative colitis patients even during remission, remaining as disease-associated molecular signatures.
37 citations
,
January 2010 in “Journal of Clinical Investigation” In this study, N-WASP deficiency in mouse skin was found to cause severe alopecia and disrupt hair follicle cycling by 5 months, highlighting its critical role in skin function and Wnt signaling.
21 citations
,
August 2024 in “Journal of Clinical Medicine” This review highlights that malnutrition, including deficiencies in proteins and micronutrients, may exacerbate allergic conditions like dermatitis and asthma by promoting inflammation, while adequate micronutrient intake supports regulatory immune responses.
37 citations
,
October 2021 in “Nutrients” This study discusses the potential association between low vitamin D levels and insulin resistance, suggesting that vitamin D deficiency may contribute to disorders like obesity and diabetes, but emphasizes the need for further research to confirm these links.
2 citations
,
September 2021 in “JCPSP. Journal of the College of Physicians & Surgeons Pakistan” In this study, researchers observed that while there were no significant microvascular abnormalities in the macula of PCOS patients, the parafoveal thickness was significantly increased in most quadrants.
60 citations
,
March 2011 in “Proceedings of the National Academy of Sciences of the United States of America” This study found that RANK-RANKL signaling regulates hair renewal and epidermal homeostasis in mice, revealing its role in initiating hair growth cycles and maintaining skin cell activity.
September 2025 in “Pakistan Journal of Science” This study observed that individuals with type 1 diabetes mellitus have notably lower levels of essential and trace elements like Calcium, Potassium, and Zinc in biological samples compared to non-diabetic controls.
January 2019 in “Revista Medicina Cutánea Ibero-Latino-Americana” This article reviews the influence of vitamin D on various dermatological diseases and suggests that vitamin D supplementation might aid in maintaining skin cell homeostasis; it reports no new clinical results.
65 citations
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May 2017 in “Advances in wound care” This review discusses the role of Toll-like receptors in wound healing and highlights their potential therapeutic value but notes that their role in human wound healing and chronic wounds is not well understood.
15 citations
,
December 2013 This study found that in men with androgenic alopecia, moderate to severe cases were associated with the AA genotype of rs1160312, blood vanadium concentrations, and regular consumption of soy bean drinks.
10 citations
,
January 2018 in “Elsevier eBooks” This review discusses the wound healing process and the factors contributing to abnormal scarring after thermal injuries, but it reports no new clinical results.
7 citations
,
January 2017 in “American Journal of Biological Anthropology” This review explores the various genetic, hormonal, environmental, and nutritional factors proposed to explain the historically shorter stature of Sardinians, while reporting no new empirical findings.
2 citations
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January 2019 in “Springer eBooks” The conclusion is that different blood diseases cause specific oral symptoms and require varied treatments to manage these symptoms and improve patient health.
2 citations
,
July 2014 in “Irish Journal of Medical Science” The meeting discussed medical findings, including benefits of certain treatments for cancer and heart conditions, and highlighted issues like poor adherence to preventive measures and skill gaps among interns.
May 2025 in “The Journal of Rheumatology” This case report describes a 47-year-old woman with dilated cardiomyopathy as the first sign of primary antiphospholipid syndrome, highlighting the need for APS screening in similar patient presentations.
237 citations
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December 2001 in “Urology” This review discusses the role of 5α-reductase in prostate development and BPH, and reports no new clinical results; ongoing trials are exploring dual isozyme inhibitors for improved treatment efficacy.