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Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.

Adult stem cells from rat whisker follicles can regenerate hair follicles and sebaceous glands.

Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.

Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.

The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.

The research shows that a gene called Wnt3 affects hair growth and structure, causing short hair and balding when overactive.

Niosomes improve minoxidil skin delivery for hair loss treatment.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

Dermatoscopy is useful for identifying different hair and scalp conditions and can reduce the need for biopsies.

Finasteride doesn't effectively treat hair loss in postmenopausal women.

Middle-aged women with chronic telogen effluvium experience increased hair shedding but usually don't get significantly thinner hair.

Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

Telogen effluvium is a reversible hair loss condition that requires a detailed diagnosis and often resolves on its own.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Noggin is necessary to start the hair growth phase in skin after birth.

Hair color production in mice is closely linked to the hair growth phase and may also influence hair growth itself.

Interferon alfa-2a is effective for treating cutaneous T cell lymphoma but has significant side effects.

The Multi-Organ-Chip improves the growth and quality of skin and hair in the lab, potentially replacing animal testing.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

PGD2 stops hair growth and is higher in bald men with AGA.

Scientists have found a way to create hair follicles from skin cells of newborn mice, which can grow and cycle naturally when injected into adult mouse skin.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

WNT10A mutations often cause ectodermal dysplasias, with males showing more tooth issues than females.

Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

Dermatologists need to understand hair products to treat hair and scalp issues better.

Minoxidil boosts growth factor in hair cells, potentially promoting hair growth.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.