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Glossary Microneedling

minimally invasive procedure using fine needles to stimulate collagen

Microneedling, also known as Collagen Induction Therapy (CIT), is a minimally invasive cosmetic procedure that involves using a device with fine needles to create tiny punctures in the skin. These micro-injuries stimulate the body's natural wound healing processes, leading to increased collagen and elastin production, which can improve skin texture, reduce scars, and promote hair growth in cases of alopecia.

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research Review of applications of microneedling in dermatology

108 citations , August 2017 in “Clinical, Cosmetic and Investigational Dermatology”

This review highlights microneedling's promise as an adjuvant therapy for enhanced drug delivery in dermatology, especially for conditions like atrophic scars and pigmentation disorders, though its efficacy for vitiligo is limited.

research Combined autologous platelet-rich plasma with microneedling verses microneedling with distilled water in the treatment of atrophic acne scars: a concurrent split-face study

106 citations , January 2016 in “Journal of Cosmetic Dermatology”

This study found that adding platelet-rich plasma to microneedling improved outcomes for atrophic acne scars more than microneedling alone, according to both quantitative and qualitative assessments.

research Microneedling: Where do we stand now? A systematic review of the literature

92 citations , June 2017 in “Journal of Plastic Reconstructive and Aesthetic Surgery”

This review found that microneedling appears to be a safe and effective option for treating scars and wrinkles, with fewer side effects and shorter recovery time than some other treatments.

research Response to microneedling treatment in men with androgenetic alopecia who failed to respond to conventional therapy

68 citations , May 2015 in “Indian Journal of Dermatology”

This case series found that adding microneedling to conventional finasteride and minoxidil therapy for androgenetic alopecia improved new hair growth and patient satisfaction in poor responders.

research Microneedling for the treatment of hair loss?

58 citations , December 2017 in “Journal of The European Academy of Dermatology and Venereology”

This review highlights that microneedling shows some promise for improving hair growth in alopecia, particularly when used with other treatments, though more research is needed to establish its efficacy and protocols.

research Alopecia areata-successful outcome with microneedling and triamcinolone acetonide

53 citations , January 2014 in “Journal of Cutaneous and Aesthetic Surgery”

Microneedling combined with triamcinolone can safely stimulate faster hair regrowth in people with Alopecia Areata.

research Micro-Needling Depth Penetration, Presence of Pigment Particles, and Fluorescein-Stained Platelets: Clinical Usage for Aesthetic Concerns

49 citations , August 2016 in “Aesthetic Surgery Journal”

This study found that micro-needling with cosmeceuticals or platelet-rich plasma significantly improved wrinkles, skin laxity, scar softening, and hair growth over 12 months, with minimal side effects, and that the best results occur with pigment and platelet massaging between 5 to 30 minutes post-treatment.

research A comparative study of microneedling with platelet-rich plasma plus topical minoxidil (5%) and topical minoxidil (5%) alone in androgenetic alopecia

48 citations , January 2017 in “International Journal of Trichology”

This study found that combining microneedling with PRP and topical minoxidil (5%) significantly improved hair growth in men with androgenetic alopecia compared to using minoxidil alone.

research Original article: Platelet-rich plasma with microneedling in androgenetic alopecia along with dermoscopic pre- and post-treatment evaluation

36 citations , August 2017 in “Journal of Cosmetic Dermatology”

In this study, patients with mild to moderate androgenetic alopecia who received platelet-rich plasma injections with microneedling showed improvements in hair growth and thickness, as well as high satisfaction, over a three-month period compared to conventional therapy non-responders.

research Microneedling dilates the follicular infundibulum and increases transfollicular absorption of liposomal sepia melanin

25 citations , June 2015 in “Clinical, Cosmetic and Investigational Dermatology”

This study found that using an electrical microneedling device enhanced the penetration of liposomal melanin-fluorescein into hair structures and widened the follicular infundibulum in ex vivo human skin models.

research Preliminary results of the use of scalp microneedling in different types of alopecia

24 citations , June 2019 in “Journal of Cosmetic Dermatology”

This study found that microneedling improved hair density and thickness with minimal side effects in patients with androgenetic alopecia and telogen effluvium.

research Platelet‐rich plasma and microneedling improves hair growth in patients ofandrogenetic alopecia when used as an adjuvant to minoxidil

24 citations , January 2019 in “Journal of Cosmetic Dermatology”

In this study, the authors reported that among patients with androgenetic alopecia, treatment with minoxidil 5% lotion combined with PRP and microneedling resulted in better hair growth and higher satisfaction compared to other treatment groups.

research A randomized controlled, single-observer blinded study to determine the efficacy of topical minoxidil plus microneedling versus topical minoxidil alone in the treatment of androgenetic alopecia

24 citations , January 2018 in “Journal of Cutaneous and Aesthetic Surgery”

This study found that combining microneedling with topical minoxidil was more effective than minoxidil alone in increasing hair count and improving patient satisfaction for men with androgenetic alopecia, though the cosmetic impact was not significant.

research Is skin microneedling a good alternative method of various skin defects removal

23 citations , September 2018 in “Dermatologic Therapy”

This article explains that skin microneedling promotes skin regeneration by creating microinjuries, which stimulate collagen and elastin production, making it effective for treating various skin issues with high effectiveness, limited side effects, and a short recovery time.

research Microneedling in Dermatology: A Comprehensive Review of Applications, Techniques, and Outcomes

21 citations , September 2024 in “Cureus”

This review explores the mechanisms, techniques, and clinical applications of microneedling, highlighting its advantages and challenges in skin rejuvenation, and discusses future innovations in the field as it continues to evolve.

research A randomized blinded retrospective study: the combined use of micro-needling technique, low-level laser therapy and autologous non-activated platelet-rich plasma improves hair re-growth in patients with androgenic alopecia

20 citations , July 2020 in “Expert Opinion on Biological Therapy”

This study found that combining micro-needling, low-level laser therapy, and autologous non-activated platelet-rich plasma increased hair density in patients with androgenic alopecia over the treatment period.

research Lasers, Microneedling, and Platelet-Rich Plasma for Skin Rejuvenation and Repair

18 citations , August 2018 in “Facial Plastic Surgery Clinics of North America”

This review summarizes the positive clinical response of using platelet-rich plasma as an adjuvant in skin rejuvenation treatments, with no identifiable complications, suggesting a promising outlook for its future use.

research Safety Profile for Microneedling: A Systematic Review

17 citations , August 2021 in “Dermatologic surgery”

This review found that microneedling is generally safe, with most adverse effects being minor and resolving quickly, though there is increased risk in patients with active infections, darker skin, or metal allergies.

research Combination of photodynamic therapy with 5‐aminolaevulinic acid and microneedling in the treatment of alopecia areata resistant to conventional therapies: our experience with 41 patients

14 citations , August 2019 in “Clinical and Experimental Dermatology”

This study suggests that combining microneedling with ALA-photodynamic therapy may be a promising treatment option for moderate to severe alopecia areata, achieving significant hair regrowth in some patients.

research Micro needling: A novel therapeutic approach for androgenetic alopecia, A Review of Literature

13 citations , September 2020 in “Dermatologic Therapy”

This review discusses the use of microneedling for androgenetic alopecia and finds it promising for enhancing hair density and thickness, especially when combined with other treatments, but notes no standardized protocol exists yet.

research Efficacy and safety of microneedling and oral tranexamic acid in the treatment of facial melasma in women: An open, evaluator-blinded, randomized clinical trial

13 citations , February 2020 in “Journal of the American Academy of Dermatology”

This study found that both oral tranexamic acid and microneedling improve melasma treatment outcomes when added to standard therapy, with microneedling showing a more sustained remission.

research Platelet-rich plasma microneedling versus 5% topical minoxidil in the treatment of patterned hair loss

13 citations , January 2016 in “Journal of the Egyptian Women's Dermatologic Society (Print)”

This abstract discusses platelet-rich plasma therapy for patterned hair loss but provides no new clinical results, suggesting further research is needed to determine its effectiveness.

research An Overview of the Biology of Platelet-Rich Plasma and Microneedling as Potential Treatments for Alopecia Areata

12 citations , December 2017 in “Journal of Investigative Dermatology Symposium Proceedings”

This review discusses platelet-rich plasma and microneedling for alopecia areata, reporting promising small-scale findings but no new results, and suggests further trials to determine efficacy and specific disease subtype suitability.

research Microneedling as a successful treatment for alopecia X in two Pomeranian siblings

12 citations , July 2015 in “Veterinary Dermatology”

This study observed that microneedling induced significant hair regrowth and reduced hyperpigmentation in two Pomeranians with alopecia X, with stable results over 12 months.

research Microneedling in androgenetic alopecia; comparing two different depths of microneedles

10 citations , September 2020 in “Journal of Cosmetic Dermatology”

In this study, microneedling with a depth of 0.6 mm, alongside minoxidil, significantly improved hair count and thickness in patients with androgenetic alopecia compared to minoxidil alone, and was more beneficial than a 1.2 mm depth.

research Randomized trial of electrodynamic microneedling combined with 5% minoxidil topical solution for treating androgenetic alopecia in Chinese males and molecular mechanistic study of the involvement of the Wnt/β-catenin signaling pathway

10 citations , May 2020 in “Journal of Dermatological Treatment”

This study found that combining microneedling with 5% minoxidil improved hair growth in Chinese men with androgenetic alopecia, possibly through activating the Wnt/β-catenin signaling pathway.

research Microneedling for Hair Loss

9 citations , October 2021 in “Journal of Cosmetic Dermatology”

This study found that microneedling monotherapy significantly increased hair count more than topical minoxidil in androgenetic alopecia, with combination therapy of microneedling and minoxidil being even more effective. Further research is needed to evaluate microneedling's safety and efficacy as a monotherapy.

research Combined Effect of Microneedling and Platelet-Rich Plasma for the Treatment of Acne Scars: A Meta-Analysis

7 citations , February 2022 in “Frontiers in Medicine”

This study found that combining microneedling with PRP was more effective than microneedling alone for improving acne scars, with higher patient satisfaction and no significant increase in severe side effects.

research Follicular Transplantation, Microneedling, and Adjuvant Narrow-band Ultraviolet-B Irradiation as Cost-Effective Regimens for Palmar-Plantar Vitiligo: A Pilot Study

7 citations , April 2020 in “Curēus”

In this pilot study, both microneedling and CO2 laser combined with hair transplantation and nbUVB demonstrated potential for inducing repigmentation in refractory palmar-plantar vitiligo, though further research is needed to ascertain their relative efficacy.

research Fractional Laser-assisted Hair Regrowth and Microneedling for the Treatment of Alopecia Areata: A Review

7 citations , June 2019 in “Cureus”

This literature review suggests that fractional lasers and microneedling, particularly when used with topical agents, may be effective treatments for alopecia areata; however, the small size and number of studies highlight a need for larger trials to confirm efficacy.