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Vitamin D made by the skin plays a role in immune defense and skin health, and more research is needed to understand its full effects.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

Off-label drug use can be risky but sometimes beneficial when standard treatments fail.

New targeted immunotherapies are improving treatment for inflammatory skin diseases.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

MEL-A from soybean oil can boost fibroblast and papilla cells, potentially aiding hair growth.

Activating TLR5 in the gut can extend lifespan and improve health in aged mice.

DHT may reduce inflammation caused by certain bacteria in skin cells.

NF-κB is crucial for zebrafish heart repair, affecting heart cell growth and repair processes.

Microbial biosurfactants could be a safer and environmentally friendly alternative to chemical surfactants in cosmetics.

Gut health affects skin diseases, and probiotics might help.

A synthetic sandalwood odorant can boost antimicrobial production in hair follicles, making them more resistant to bacteria.

Fermenting Dendrobium officinale with Lactobacillus reuteri CCFM8631 increases its skin care benefits.

RANKL improves the immune response against herpes simplex virus by enhancing T cell activation and could help develop better treatments or vaccines.

Mannosylerythritol lipids are good for skin and hair care products.

Sensitive skin is often caused by nerve fibers and environmental factors, and can be managed with mild skincare and professional advice.

Skin fat helps with body temperature control and has other active roles in health.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.

The PRP-like cosmetic product with postbiotics effectively treats hair loss in Alopecia areata.

Bacteria in our hair can affect its health and growth, and studying these bacteria could help us understand hair diseases better.

New technologies help us better understand how skin microbes affect skin diseases.

A new mutation in the TMEM173 gene and a risk allele in IFIH1 cause a unique set of immune-related symptoms.

The microbiome may be linked to hair loss and could be a target for new treatments.

Behçet's Disease may be caused by genetic and environmental factors leading to abnormal immune responses, and stress management and new treatments could improve patient outcomes.

Men are more likely to have severe respiratory viral infections like COVID-19 due to hormonal and genetic differences, while women generally have stronger immune responses.

The document concludes that better understanding the wound microbiome can improve chronic wound care by preserving helpful bacteria and targeting harmful ones.

Blue light might help treat skin conditions by affecting the skin's bacteria.

Cynoglossum amabile has medicinal potential but poses safety concerns due to liver toxicity.

Applying pseudoceramide improved skin and hair health.