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Engineering the cell microenvironment is key for advancing tissue engineering and regenerative medicine.

Wounds can regenerate hair in young mice, but this ability declines with age, offering insights for improving tissue regeneration in the elderly.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

IL-6 from stem cells helps repair skin and grow hair.

Male hormones cause different growth in identical human hair follicles due to their unique epigenetic characteristics.

The study found new details about human hair growth and suggests that preventing a specific biological pathway could potentially treat hair graying.

The research suggests immune system changes and specific gene expression may contribute to male hair loss, proposing potential new treatments.

Ginkgo biloba polysaccharides may reduce inflammation and promote hair growth in mice with hair loss.

Stem cells, especially from fat tissue and Wharton's jelly, can potentially regenerate hair follicles and treat hair loss, but more research is needed to perfect the treatment.

Smaller curcumin nanocrystals penetrate skin and hair follicles better than larger ones.

Electrospun matrices help regenerate skin and hair follicles using PCL and collagen scaffolds.

Human hair follicle stem cells can be isolated using specific markers for potential therapeutic use.

Hair follicle stem cells change states with age, affecting hair growth and aging.

Immune cells are essential for early hair and skin development and healing.

Overactivating Hedgehog signaling makes hair follicle cells in mice grow hair faster and create more follicles.

Nano-sized lipid particles increase dexamethasone's skin penetration and create a reservoir in the skin layers.

Dandruff is linked to increased T cells and weakened immune protection in hair follicles.

Fat cells are important for tissue repair and stem cell support in various body parts.

The engineered skin substitute helped grow skin with hair on mice.

Special proteins are important for skin balance, healing, and aging, and affect skin stem cells.

Different types of stem cells and their environments are key to skin repair and maintenance.

The document concludes that both internal stem cell factors and external influences like the environment and hormones affect hair loss and aging, with potential treatments focusing on these areas.

The study showed that some hair follicle stem cells wake up to grow hair while others stay asleep, and that the environment around them is important for hair growth.

Exosomes could be effective for improving skin health and treating skin diseases.

Skin bacteria, specifically Staphylococcus aureus, help in wound healing and hair growth by using IL-1β signaling. Using antibiotics on skin wounds can slow down this natural healing process.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Skin stem cells are maintained by signals from nearby cells and vary in their ability to renew and mature.

Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.

Different cell types work together to repair skin, and targeting them may improve healing and reduce scarring.

Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.