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      COVID-19 and Sex Differences: Mechanisms and Biomarkers

      research COVID-19 and Sex Differences

      185 citations , August 2020 in “Mayo Clinic Proceedings”
      This review discusses biological sex differences in COVID-19 outcomes and reports no new clinical results; it identifies a need for studies to clarify how sex influences disease progression.
      Wound Healing and the Use of Medicinal Plants

      research Wound Healing and the Use of Medicinal Plants

      170 citations , September 2019 in “Evidence-based Complementary and Alternative Medicine”
      This review discusses the use of 36 medicinal plant species for cutaneous wound healing and reports no new clinical results; the authors highlight the potential for these traditional practices to inform modern therapies.
      Alopecia Areata: A Multifactorial Autoimmune Condition

      research Alopecia areata: A multifactorial autoimmune condition

      148 citations , December 2018 in “Journal of autoimmunity”
      This review discusses genetic and environmental factors contributing to autoimmunity in alopecia areata and reports no new clinical findings, emphasizing the need for further study on its aetiology and pathophysiology.
      The Immune Functions of Keratinocytes in Skin Wound Healing

      research The Immune Functions of Keratinocytes in Skin Wound Healing

      147 citations , November 2020 in “International Journal of Molecular Sciences”
      This review discusses the immune roles of keratinocytes in wound healing and chronic wound inflammation, emphasizing their potential impact on chronic wound pathology and highlighting areas for future research.
      TGF-β Family Signaling in Stem Cells

      research TGF-β family signaling in stem cells

      132 citations , August 2012 in “Biochimica et Biophysica Acta (BBA) - General Subjects”
      This review discusses the roles of TGF-β family signaling in regulating normal and cancer stem cells and highlights the need for further research to develop potential cancer treatments; it reports no new results.
      Tregs: Where We Are and What Comes Next?

      research Tregs: Where We Are and What Comes Next?

      130 citations , November 2017 in “Frontiers in Immunology”
      This review explores recent findings on regulatory T cells, focusing on their unique functions in non-lymphoid tissues and new mechanisms of action, but presents no original clinical results.
      Hormesis And Medicine: Biphasic Dose-Response Relationship

      research Hormesis and medicine

      127 citations , June 2008 in “British Journal of Clinical Pharmacology”
      This study supports the conclusion that the hormetic dose-response model is the most prevalent and fundamental model in biological and biomedical sciences, applicable to a wide range of clinical conditions.
      Targeting the Janus Kinase Family in Autoimmune Skin Diseases

      research Targeting the Janus Kinase Family in Autoimmune Skin Diseases

      124 citations , October 2019 in “Frontiers in Immunology”
      This review discusses the role of the JAK-STAT pathway in autoimmune skin diseases and suggests potential therapeutic benefits of JAK inhibitors, but reports no new experimental results.
      Cell Death in the Skin: Mechanisms and Implications

      research Cell death in the skin

      120 citations , February 2009 in “Apoptosis”
      This review examines apoptotic and anti-apoptotic mechanisms in skin homeostasis and related diseases but presents no new research findings.
      Covid-19 Vaccines While Pregnant Or Breastfeeding

      research COVID-19 vaccines while pregnant or breastfeeding

      118 citations , November 2024 in “World Journal of Biology Pharmacy and Health Sciences”
      This study highlights that the ACIP strongly recommends COVID-19 vaccination and booster doses for pregnant women, those breastfeeding, or trying to conceive, due to the safety of non-live vaccines in these groups and the protection they also offer to infants.
      Review of Applications of Microneedling in Dermatology

      research Review of applications of microneedling in dermatology

      108 citations , August 2017 in “Clinical, Cosmetic and Investigational Dermatology”
      This review highlights microneedling's promise as an adjuvant therapy for enhanced drug delivery in dermatology, especially for conditions like atrophic scars and pigmentation disorders, though its efficacy for vitiligo is limited.
      Hair Follicle Immune Privilege Revisited: The Key to Alopecia Areata Management

      research Hair Follicle Immune Privilege Revisited: The Key to Alopecia Areata Management

      102 citations , December 2017 in “˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings”
      This review discusses the role of immune privilege collapse in the pathogenesis of alopecia areata, emphasizing the potential for therapeutic manipulation of hair bulb immune privilege to offer new treatment options, and reports no new results.
      Sensitive Skin

      research Sensitive skin

      94 citations , January 2016 in “Journal of the European Academy of Dermatology and Venereology”
      Sensitive skin is often caused by nerve fibers and environmental factors, and can be managed with mild skincare and professional advice.
      Stratum Corneum Dysfunction in Dandruff

      research Stratum corneum dysfunction in dandruff

      93 citations , April 2012 in “International Journal of Cosmetic Science”
      This article discusses the role of stratum corneum disruption in dandruff and suggests that treatments improving scalp barrier integrity along with antifungal activity may be beneficial; it reports no new research findings.
      Dermal White Adipose Tissue: A New Component of the Thermogenic Response

      research Dermal white adipose tissue: a new component of the thermogenic response

      92 citations , September 2015 in “Journal of Lipid Research”
      This review discusses the roles of dermal white adipose tissue (dWAT) as an insulator, antibiotic, and regenerative tissue, highlighting its importance in systemic metabolism and immune function, but reports no new clinical results.
      FOXO1, TGF-β Regulation and Wound Healing

      research FOXO1, TGF-β Regulation and Wound Healing

      87 citations , September 2014 in “International Journal of Molecular Sciences”
      This study found that the transcription factor FOXO1 plays a crucial role in wound healing by protecting keratinocytes from oxidative stress and regulating TGF-β expression.
      Antioxidants in Dermatology

      research Antioxidants in dermatology

      86 citations , June 2017 in “Anais Brasileiros de Dermatologia”
      This review discusses the role of antioxidants in managing oxidative skin damage and reports no new results, emphasizing the need for understanding their mechanisms, limitations, and risks for safe use.
      Nanozymes Expanding the Boundaries of Biocatalysis

      research Nanozymes expanding the boundaries of biocatalysis

      85 citations , July 2025 in “Nature Communications”
      This review examines the evolving field of nanozymes, highlighting their unique properties and biocatalytic capabilities that challenge traditional concepts of biocatalysis, with implications for sustainable applications and potential roles in physiological processes and disease pathogenesis.
      Human αβ and γδ T Cells in Skin Immunity and Disease

      research Human αβ and γδ T Cells in Skin Immunity and Disease

      83 citations , June 2018 in “Frontiers in immunology”
      This review discusses the roles of αβ and γδ T cells in skin health and disease and reports no new clinical results; the authors highlight potential therapeutic developments.
      Ubiquity and Diversity of Human-Associated Demodex Mites

      research Ubiquity and Diversity of Human-Associated Demodex Mites

      83 citations , August 2014 in “PLoS ONE”
      This study suggests that Demodex mites might universally inhabit adult humans, with a phylogenetic analysis indicating potential undiscovered lineages of the D. brevis species based on geographic differences.