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      research BroadAMP-GPT: AI-Driven generation of broad-spectrum antimicrobial peptides for combating multidrug-resistant ESKAPE pathogens

      12 citations , June 2025 in “Gut Microbes”
      This study developed BroadAMP-GPT, a computational-experimental framework, to discover new antimicrobial peptides, identifying candidates effective against multidrug-resistant pathogens. Notably, AMP_S13 showed strong stability, low toxicity, and efficacy in infection models, highlighting the platform's potential in combating antimicrobial resistance.
      Bacteria Induce Skin Regeneration via IL-1β Signaling

      research Bacteria induce skin regeneration via IL-1β signaling

      53 citations , April 2021 in “Cell Host & Microbe”
      This study found that skin microbiota, particularly in wild-type mice, promotes wound-induced hair follicle neogenesis and wound healing, highlighting the potential downsides of routine antibiotic use on skin regeneration.
      Unveiling the Connection Between Gut Microbiome and Polycystic Ovary Syndrome

      research Unveiling the Connection between Gut Microbiome and Polycystic Ovary Syndrome (PCOS)

      October 2025 in “Progress In Microbes & Molecular Biology”
      This review reveals that PCOS is consistently linked to gut microbiota dysbiosis, characterized by reduced microbial diversity and shifts in composition, which are associated with various PCOS phenotypes and may present opportunities for microbiota-targeted therapies addressing the disorder's underlying pathophysiological mechanisms.
      Scratching the Surface of Skin Development

      research Scratching the surface of skin development

      788 citations , February 2007 in “Nature”
      This review explores how adult skin epithelia preserve stem cell populations for hair follicle regeneration and wound healing, but reports no new experimental results.
      Epithelial Skin Biology: Stem Cells and Epidermal Homeostasis

      research Epithelial Skin Biology

      118 citations , January 2016 in “Current Topics in Developmental Biology”
      This essay discusses the establishment, maintenance, and role of skin stem cells in tissue homeostasis, wound repair, and their relation to skin cancer, without reporting new experimental findings.
      Building Epithelial Tissues From Skin Stem Cells

      research Building Epithelial Tissues from Skin Stem Cells

      84 citations , January 2008 in “Cold Spring Harbor Symposia on Quantitative Biology”
      This article reviews recent advancements in understanding skin stem cells and their roles in maintaining epidermal homeostasis and repairing wounds, without presenting new experimental findings.
      Regulating Hair Follicle Stem Cells

      research T-Regulating Hair Follicle Stem Cells

      14 citations , June 2017 in “Immunity”
      This study found that skin-resident Treg cells regulate hair follicle stem cell proliferation and differentiation through the Jag1-Notch signaling pathway, influencing hair regeneration.
      Dissecting the Roles of Innate Cells in the Skin and Intractable Skin Diseases

      research Dissecting the Roles of Innate Cells in the Skin and Intractable Skin Diseases

      1 citations , January 2022 in “The Keio Journal of Medicine”
      This research describes how hair follicles regulate skin immune cells and how disruption in certain signaling pathways can lead to skin dysbiosis and inflammation; it also highlights the role of macrophages in protecting against cellulitis in mice.
      Licorice: A Review on Phytochemical Insights and Therapeutic Potential

      research Licorice: A review on phytochemical insights and therapeutic potential

      September 2025 in “Journal of Phytonanotechnology and Pharmaceutical Sciences”
      This comprehensive review reports on the therapeutic potential and bioactive components of licorice (Glycyrrhiza glabra Linn), highlighting its diverse pharmacological properties and health benefits but also noting associated toxicity and adverse effects in medicinal and food applications.
      A Perspective on RNAi-Based Biopesticides

      research A Perspective on RNAi-Based Biopesticides

      140 citations , February 2020 in “Frontiers in Plant Science”
      This article discusses the potential of RNA-based biopesticides for sustainable agriculture and reports no new experimental results; it highlights the need for improved delivery systems and regulatory development to enhance deployment.
      The Role of Micronutrients and Thyroid Function Tests in Pediatric Hair Loss

      research The Role of Micronutrients and Thyroid Function Tests in Pediatric Hair Loss

      September 2025 in “Online Türk Sağlık Bilimleri Dergisi”
      This study observed that pediatric patients with diffuse, non-scarring alopecia had significantly lower levels of zinc and folate compared to matched healthy controls, suggesting a possible link between these deficiencies and hair loss in children.
      The Human Microbiome: A Critical Player in Health and Disease

      research The human microbiome: A critical player in health and disease

      3 citations , August 2023 in “World Journal of Biology and Biotechnology”
      This research underscores the critical role of the human microbiome in health, highlighting potential therapeutic benefits of interventions like fecal microbiota transplantation and probiotics for conditions linked to microbiome dysbiosis, such as metabolic disorders and inflammatory diseases.
      Effects of Sex Steroid Deprivation and Administration on Hair Growth and Skin Sebum Production in Transsexual Males and Females

      research Effects of Sex Steroid Deprivation/Administration on Hair Growth and Skin Sebum Production in Transsexual Males and Females

      176 citations , August 2000 in “˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism”
      In this study, cross-sex hormone therapy affected hair growth patterns differently, with estrogen reducing hair growth in male-to-female transsexuals and testosterone increasing it in female-to-male transsexuals; however, male typical hair diameters were not fully reached in the latter group after 12 months.
      Anthracycline Analogs: The Past, Present, And Future

      research Anthracycline analogs The past, present, and future

      168 citations , December 1986 in “Cancer Chemotherapy and Pharmacology”
      Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.
      Probiotic Bacteria Induce a Glow of Health

      research Probiotic Bacteria Induce a ‘Glow of Health’

      127 citations , January 2013 in “PLOS ONE”
      This study found that feeding aged mice a probiotic yogurt induced changes leading to thicker, healthier fur, suggesting a bacteria-triggered interleukin-10-dependent mechanism that mimics signs of youth and reproductive fitness.
      Regulatory T Cells in Skin: Role of Foxp3+ CD4+ Tregs in Skin Homeostasis and Immune Tolerance

      research Regulatory T cells in skin

      110 citations , July 2017 in “Immunology”
      This review discusses the role of regulatory T cells in skin, including their impact on hair follicle regeneration, wound healing, and immune tolerance, without presenting new clinical findings.
      Local Heroes or Villains: Tissue-Resident Memory T Cells in Human Health and Disease

      research Local heroes or villains: tissue-resident memory T cells in human health and disease

      67 citations , January 2020 in “Cellular & Molecular Immunology/Cellular & molecular immunology”
      This review discusses the dual role of tissue-resident memory T cells in providing immune protection against infections and cancer and contributing to autoimmune skin disease pathology, without presenting new experimental results.
      Toll-Like Receptor Function in Acute Wounds

      research Toll-Like Receptor Function in Acute Wounds

      65 citations , May 2017 in “Advances in wound care”
      This review discusses the role of Toll-like receptors in wound healing and highlights their potential therapeutic value but notes that their role in human wound healing and chronic wounds is not well understood.
      Strategic Targets in Acne: The Comedone Switch in Question

      research Strategic Targets in Acne: The Comedone Switch in Question

      47 citations , January 2015 in “Dermatology”
      This review revisits mechanisms underlying acne lesion formation and suggests that preventing comedone development requires controlling critical factors in the pilosebaceous follicle before acne involvement.
      Functional Skin Grafts: Where Biomaterials Meet Stem Cells

      research Functional Skin Grafts: Where Biomaterials Meet Stem Cells

      43 citations , July 2019 in “Stem Cells International”
      This review discusses advances and challenges in skin tissue engineering, focusing on developing 3D constructs for functional skin substitutes, and reports no new clinical results.