109 citations
,
December 2003 in “American Journal of Pathology” This study observed that the ontogenetic transition from scarless repair in early fetal rat wounds to scar-forming repair in late gestation is associated with differential TGF-β ligand and receptor expression patterns.
69 citations
,
April 2019 in “Biomedicines” This study found that hair thickness and density increased after treatment with human follicle mesenchymal stem cells and platelet rich plasma, associated with enhanced Wnt signaling and platelet derived growth factors.
67 citations
,
April 2007 in “Journal der Deutschen Dermatologischen Gesellschaft” This article reviews the development and formulation of shampoos, emphasizing their dual role as cosmetic and medicinal products, but presents no new experimental findings.
65 citations
,
April 2020 in “International Journal of Molecular Sciences” This review indicates that most studies reported positive effects of platelet-rich plasma injections for treating androgenic alopecia, with no major side effects, suggesting it may be a safe alternative to Minoxidil and Finasteride.
62 citations
,
April 2008 in “Neurobiology of aging” This study identified a new genetic locus, ahl4, on distal Chromosome 10 that contributes to the early-onset, severe hearing loss in A/J mice compared to B6 mice.
53 citations
,
June 2017 in “Skin appendage disorders” This review suggests that platelet-rich plasma may be effective in increasing hair density in patients with androgenetic alopecia, but more research is needed to determine the best treatment protocol.
52 citations
,
May 2017 in “Journal of Cosmetic Dermatology” This study found that platelet-rich plasma injections significantly improved hair density, thickness, and patient satisfaction in women with female pattern hair loss compared to a placebo.
52 citations
,
January 2004 in “Medical mycology” This study reported an increase in tinea capitis in Stockholm children, mainly caused by Trichophyton violaceum and associated with immigration from Africa and family spread.
36 citations
,
July 2016 in “Scientific reports” This study found that decision-making effects related to time of day and chronotype were only significant when using RNA-based chronotype measurements, indicating molecular clock differences may influence these behaviors.
35 citations
,
May 2012 in “Cochrane Database of Systematic Reviews” This review found evidence supporting the effectiveness and safety of topical minoxidil for treating female pattern hair loss, though many included studies were at high risk of bias.
35 citations
,
October 2004 in “Biology of Reproduction” This study found that dual 5α-reductase inhibition in rats led to decreased sperm motility and altered morphology, resulting in subfertility.
34 citations
,
January 1977 in “American Journal of Cardiology”
33 citations
,
September 2016 in “Lasers in Surgery and Medicine” In this review, the authors report that fractional resurfacing can be a safe and effective technique for treating scars and promoting photorejuvenation in Asian skin, though it requires cautious use to minimize risks like post-inflammatory hyperpigmentation and rebound melasma.
27 citations
,
June 2019 in “Aesthetic Plastic Surgery” Platelet-Rich Plasma (PRP) treatment may increase hair growth for genetic hair loss, but more research is needed to confirm this.
25 citations
,
July 2017 in “Journal of Stomatology, Oral and Maxillofacial Surgery” This review suggests that PRP injections may be effective in promoting hair regrowth, reducing hair loss, and increasing hair thickness in patients with androgenic alopecia.
25 citations
,
August 2016 in “Journal of Cosmetic Dermatology” This study found that a marine complex supplement significantly reduced hair shedding and increased hair growth in men with thinning hair over 180 days.
25 citations
,
August 2015 in “Journal of cosmetic dermatology” This study observed significant differences in hair care practices and biologic hair parameters between Caucasian and African American women, which may contribute to varying hair fragility and growth.
25 citations
,
November 2001 in “Kidney International” This study suggests that dihydrotestosterone plays a key role in the development of chronic allograft nephropathy, and inhibiting androgens may improve long-term kidney transplant outcomes.
24 citations
,
May 2013 in “Drug Design Development and Therapy” This pilot study found that a multimodal minoxidil microemulsion with diclofenac and tea tree oil was more effective and safer than minoxidil alone for treating androgenic alopecia over 32 weeks.
24 citations
,
January 2006 in “Skin Pharmacology and Physiology” This study found that finasteride (1 mg/day) appeared to reverse the shortening of the hair cycle in androgen sensitive sites but did not convert miniaturized hair into terminal hair.
23 citations
,
August 2012 in “Veterinary dermatology” This study found that feline superficial pyoderma was more prevalent in the dermatology-referral cats studied than previously reported, affecting mainly young cats with hypersensitivities and manifesting various lesion types.
22 citations
,
October 2018 in “Aesthetic Plastic Surgery” This review discusses the latest understanding of androgenetic alopecia, including stem cell niches in hair follicles, and highlights emerging treatments like growth factors and platelet-rich plasma without new clinical findings.
21 citations
,
May 2016 in “The Cochrane library” This review found that while topical minoxidil is effective for treating female pattern hair loss, finasteride showed no more effectiveness than placebo, and low-level laser therapy increased hair count but with inconsistent results.
18 citations
,
November 2016 in “Journal of Oral and Maxillofacial Surgery” This review discusses platelet-rich plasma for androgenic alopecia and reports beneficial effects on hair density and quality, but suggests more rigorous studies are needed for conclusive evidence.
13 citations
,
October 2012 in “InTech eBooks” Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.
9 citations
,
January 2011 in “Skin Research and Technology” This study developed a high-resolution phototrichogram system that can automatically and accurately assess hair growth metrics in cosmetic trials, achieving over 90% correlation with manual measurements.
7 citations
,
November 2013 in “Pediatric and Developmental Pathology” This retrospective review of hair samples from pediatric patients indicated that microscopic hair examination might be a useful first-line investigation for diagnosing various genetic conditions.
7 citations
,
April 2011 in “Aktuelle Dermatologie” This study aimed to examine the effects of a nutritional formula containing fenugreek seed extract and micronutrients on androgenetic alopecia, but it reports no new clinical results.
6 citations
,
September 2019 in “Journal of Cosmetic Dermatology” In this study, patients with androgenic alopecia who underwent 10 sessions of 1540-nm fractional erbium glass laser treatment over 5 months experienced significant improvements in hair density and thickness, with no major safety concerns reported.
6 citations
,
January 2015 in “Dermatology” This review covers trichoscopy's role in diagnosing scalp disorders, emphasizing its potential to improve clinical accuracy, but it reports no new clinical results.