224 citations
,
February 2013 in “The Journal of clinical investigation/The journal of clinical investigation” This study identifies SOX9 as a critical downstream effector of ERG in TMPRSS2:ERG fusion-positive prostate cancer, indicating its role in tumor invasion and growth.
166 citations
,
November 2008 in “Expert Review of Endocrinology & Metabolism” This review discusses biotin and biotinidase deficiencies, their symptoms, and methods of medical management, without presenting new clinical findings.
128 citations
,
January 2023 in “Frontiers in Endocrinology” This review discusses recurrent implantation failure (RIF) in IVF, noting the lack of standard definitions or treatment protocols, and emphasizes the need for individualized treatment and further research.
107 citations
,
October 2014 in “PeerJ” This study found that while molecular hair structures were nearly identical across individuals, genetic factors seem to influence specific lipid compositions, as seen in identical-patterned hair from parent-child pairs and identical twins, but not fraternal twins.
80 citations
,
April 2006 in “Clinical Interventions in Aging” This review discusses factors affecting hair aging and the current pharmacological treatments for androgenetic alopecia, mentioning topical minoxidil and oral finasteride, but does not present new clinical findings.
72 citations
,
July 2022 in “Frontiers in Systems Biology” This review provides a comprehensive guide to the human microbiome and reports no new experimental results; it highlights the impact of modern lifestyles on microbial homeostasis and the necessity of conservation efforts.
63 citations
,
September 2020 in “Frontiers in Microbiology” This review discusses the potential health benefits of probiotics as a "Bio-Therapy" in food and medicine, noting that more research is needed to fully understand their mechanisms and effectiveness.
55 citations
,
October 2020 in “Frontiers in Pharmacology” This review discusses the role of endolysosomes in SARS-CoV-2 infection and COVID-19 pathogenesis, and explores potential therapeutic strategies targeting these cellular structures, but reports no new clinical findings.
39 citations
,
January 2013 in “Journal of Investigative Dermatology” This review explains how recent understanding of Wnt signaling regulation in hair follicles could potentially be used to enhance hair growth, but it reports no new empirical results.
27 citations
,
May 2019 in “Jo'jig gonghag gwa jaesaeng uihag/Tissue engineering and regenerative medicine” This review discusses strategies and translational advancements in urethral tissue engineering, concluding that a combination of hypoxia-preconditioned mesenchymal stem cells on pre-vascularized synthetic scaffolds may be most effective; it reports no new clinical results.
24 citations
,
January 2011 in “International Journal of Trichology” This review highlights the light microscopic features of various infectious and non-infectious hair conditions and reports no new clinical results.
17 citations
,
January 2023 in “Frontiers in Pharmacology” This study found that 10,11-dibrominecrebanine (2Br-Cre) and Stephanine demonstrate significant anti-inflammatory and analgesic properties in various experimental models, with 2Br-Cre showing enhanced efficacy over Cre and both compounds potentially mediating their analgesic effects through opioid receptors.
16 citations
,
January 2021 in “Frontiers in veterinary science” This study found no significant difference in hair cortisol concentrations, a chronic stress indicator, between sows in farrowing crates and those in loose-housing systems.
14 citations
,
January 2023 in “Nature Immunology” iNKT cells help develop and maintain healthy skin in young mice.
14 citations
,
January 2018 in “Endocrine” This report describes a three-generation family with Cantú syndrome linked to a novel ABCC9 gene variant, featuring acromegaloid appearance and hypertrichosis without growth hormone abnormalities, and suggests a potential association with pituitary adenomas.
7 citations
,
May 2022 in “Frontiers in Cell and Developmental Biology” This review discusses the molecular mechanisms driving hair follicle degeneration in skin aging and emphasizes the role of the tissue microenvironment on stem cell function, but reports no new research findings.
7 citations
,
January 2022 in “Scientific Reports” This study found that Acanthus ebracteatus extract and verbascoside induced dermal papilla cell proliferation and reduced inflammatory cytokine release in vitro, suggesting potential for anti-hair loss applications.
6 citations
,
January 2024 in “Journal of Biotechnology and Biomedicine” This review discusses the connections between atopic dermatitis and alopecia areata, emphasizing shared mechanisms and potential overlapping treatments, but it does not report new clinical findings.
6 citations
,
October 2020 in “Frontiers in cell and developmental biology” This study found that WWOX deficiency in mice leads to impaired skin development, reduced epidermal thickness, and significant hypothermia due to disrupted cell proliferation and homeostasis.
6 citations
,
October 2020 in “Journal of the European Academy of Dermatology and Venereology” This article introduces teletrichoscopy as a method for diagnosing hair disorders during the COVID-19 pandemic and reports no new clinical results.
5 citations
,
October 2021 in “Frontiers in Cell and Developmental Biology” This study examined aging hair follicle stem cells in mice and found that inflammation reduction in dermal white adipose tissue can stimulate regenerative behavior, highlighting its role in hair follicle aging.
5 citations
,
February 2019 in “PloS one” This study found that structural defects in the hair shafts of sighthounds with bald thigh syndrome are related to a downregulation of genes and proteins essential for hair shaft formation.
4 citations
,
June 2016 in “Journal of Pharmacopuncture” This study found that Cornu cervi pantotrichum pharmacopuncture solution significantly promoted hair growth in mice by enhancing hair follicular cell proliferation and up-regulating FGF-7 expression.
This study found that hair follicles across mouse skin form a heterogeneous regenerative field, with distinct cycling dynamics influenced by the balance of activator and inhibitor signals, which could inform other organ regeneration research.
2 citations
,
January 2023 in “Frontiers in Veterinary Science” This study found that although Stephanofilaria infection worsens buffalo fly lesion severity, other factors like bacterial infection and hypersensitivity to buffalo fly feeding also play significant roles.
2 citations
,
January 2023 in “Frontiers in Genetics” This study found that overexpression of ovine β-catenin in transgenic mice increased hair follicle density by promoting the transition from catagen to anagen.
2 citations
,
November 2022 in “Frontiers in Pharmacology” This study systematically documented the ethnobotanical and ethnomedicinal knowledge from traditional healers in Addis Ababa, identifying 81 medicinal plants, including the endangered Echinops kebericho, used primarily for treating skin and general diseases.
2 citations
,
July 2022 in “Frontiers in Cardiovascular Medicine” This review discusses the pharmacological activities and mechanisms of forsythiasides, highlighting their potential therapeutic value, but reports no new clinical results.
1 citations
,
January 2023 in “Frontiers in genetics” This study identified specific genetic markers related to wool quality in Rambouillet sheep, which may aid breeders in making informed selection and breeding decisions for improved fine wool production.
1 citations
,
July 2022 in “Frontiers in Microbiology” This study found that dietary supplementation with 0.2% MSM improved hair quality in kittens and had no significant negative effects on their growth performance, antioxidant capacity, or gut microbiota.