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Hair follicles may help teach the immune system to tolerate new self-antigens, but this can sometimes cause hair loss.

RANKL improves the immune response against herpes simplex virus by enhancing T cell activation and could help develop better treatments or vaccines.

A specific DNA region is crucial for Foxn1 gene expression in thymus cells but not in hair follicles.

Hair loss treatment caused more hair loss in a man.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Hair follicles offer promising targets for delivering drugs to treat hair and skin conditions.

Skin stem cells are maintained by signals from nearby cells and vary in their ability to renew and mature.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

The document concludes that the immune-inhibitory environment of the hair follicle may prevent melanoma development.

The review highlights the importance of stem cells in hair health and suggests new treatment strategies for hair loss conditions.

The skin protects the body, regulates temperature, senses touch, and makes vitamin D.

Restoring immune privilege in hair follicles could help treat certain types of hair loss.

ILC1 cells contribute to hair loss in alopecia areata.

Removing Lrig1-positive stem cells in mice causes temporary loss of sebaceous glands.

Electrical epilation damages hair follicles and surrounding skin, likely preventing hair regrowth.

The study found that sweat glands normally suppress immune responses, but this is disrupted in certain skin diseases, possibly contributing to their development.

DNA methylation changes are linked to hair growth cycles in goats.

GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.

The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.

Cyclosporine A can reduce inflammation in dogs with sebaceous adenitis, but ongoing treatment is needed.

A 3-year-old boy lost all his hair due to a rare reaction to phenobarbital, but it grew back after steroid treatment.

Scientists found key proteins and genes that affect skin and hair health, and identified potential new treatments for hair loss, skin disorders, and wound healing.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

The Middle East and Africa need better data, treatment consensus, and support for Alopecia Areata.

The nail matrix has a reduced immune response, protecting it from autoimmunity.

Controlled delivery of specific RNA and IL-4 restored hair growth in mice with autoimmune alopecia.

UV light helped human hair transplants survive in mice without broad immunosuppression.

Alopecia areata involves both innate and adaptive immunity, with specific genes linked to the disease.

Hepatitis B virus exposure may be linked to increased risk of alopecia areata.