Search
for

    Glossary Metyrapone

    Metyrapone is a medication primarily used to test adrenal function by inhibiting the enzyme 11β-hydroxylase, which is involved in cortisol synthesis. Its relevance to hair loss lies in its potential effects on hormonal balance, particularly cortisol levels, which can influence hair growth and loss. Elevated cortisol levels are often associated with stress-related hair loss conditions, making metyrapone a point of interest in understanding the hormonal pathways that affect hair biology. Key distinguishing characteristics include its role in diagnosing adrenal insufficiency and its impact on steroid metabolism.

    Sort by

    Research 30 of 58

    1. METYRAPONE AS A BRIDGING THERAPY IN FLORID CUSHING’S DISEASE PATIENT PRIOR TO PITUITARY ADENOMECTOMY Journal of the ASEAN Federation of Endocrine Societies · 2023
    2. Role of GABA-active neurosteroids in the efficacy of metyrapone against cocaine addiction Behavioural Brain Research · 2014 · 15 citations
    3. Persistent escalation of alcohol consumption by mice exposed to brief episodes of social defeat stress: suppression by CRF-R1 antagonism 2018 · 38 citations
    4. 11β-Hydroxylase inhibitors protect against seizures in mice by increasing endogenous neurosteroid synthesis Neuropharmacology · 2011 · 18 citations
    5. Hydroxylation of dehydroepiandrosterone in human scalp hair folhcles British Journal of Dermatology · 1979 · 11 citations
    6. Transient treatment of pregnant Merino ewes with modulators of cortisol biosynthesis coinciding with primary wool follicle initiation alters lifetime wool growth Animal Production Science · 2013 · 7 citations
    7. Role of neurosteroids in ischemic postconditioning-induced attenuation of cerebral ischemia-evoked neuronal injury and behavioral deficits in mice Der pharmacia lettre · 2015 · 1 citations
    8. P-50 WE KNOW YOU ARE THERE: MISSING MASS JCEM Case Reports · 2025
    9. PSAT001 A Case of Ectopic Cushing's Syndrome Complicated by COVID-19 Infection Journal of the Endocrine Society · 2022
    10. SAT-271 Block and Replace Therapy Successfully Improved Symptoms in Recurrent Cyclic Cushing’s Disease Journal of the Endocrine Society · 2020
    11. Bound on the Risk for M-SVMs HAL (Le Centre pour la Communication Scientifique Directe) · 2002
    12. Role of neurosteroids in the anticonvulsant activity of midazolam British Journal of Pharmacology · 2011 · 28 citations
    13. Drug-Induced Hair Loss and Hair Growth Drug Safety · 1994 · 147 citations
    14. Long-term opioid ADR management in cancer patients Reactions Weekly · 1994
    15. Telogen Effluvium Archives of Dermatology · 1993 · 214 citations
    16. Mechanisms of Disease: selective inhibition of 11β-hydroxysteroid dehydrogenase type 1 as a novel treatment for the metabolic syndrome Nature Clinical Practice Endocrinology & Metabolism · 2005 · 69 citations
    17. COVID-19 and endocrine and metabolic diseases. An updated statement from the European Society of Endocrinology Endocrine · 2021 · 68 citations
    18. Coat condition, housing condition and measurement of faecal cortisol metabolites - a non-invasive study about alopecia in captive rhesus macaques (Macaca mulatta) Journal of Medical Primatology · 2005 · 51 citations
    19. Update on the dermatologic use of systemic glucocorticosteroids Dermatologic Therapy · 2007 · 40 citations
    20. Hair problems in women Clinics in Dermatology · 1997 · 37 citations
    21. The effect of finasteride and dutasteride on the synthesis of neurosteroids by glioblastoma cells Steroids · 2019 · 19 citations
    22. Hyperandrogenism in Adolescent Girls Endocrine development · 2012 · 14 citations
    23. Androgenic Alopecia Dermatologic Clinics · 1987 · 14 citations
    24. Progestogens in menopausal hormone therapy Przeglad Menopauzalny · 2015 · 10 citations
    25. Hyperandrogenism in Adolescent Girls KARGER eBooks · 2004 · 10 citations
    26. Treatment of androgen excess in females: Yesterday, today and tomorrow Gynecological Endocrinology · 1997 · 9 citations
    27. Focal and Generalized Alopecia Veterinary Clinics of North America: Small Animal Practice · 1995 · 9 citations
    28. The Role of Cytochrome P-450 in Dermatology International Journal of Dermatology · 1989 · 8 citations
    29. Hyperadrenocorticism in Ferrets 2013 · 6 citations
    30. Cushing's syndrome in the elderly: data from the European Registry on Cushing's syndrome European journal of endocrinology · 2023 · 5 citations