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    Glossary Methylxanthine

    Methylxanthine refers to a class of compounds that includes caffeine, theobromine, and theophylline, which are known for their stimulant effects. In the context of hair loss and hair biology, methylxanthines have been studied for their potential to promote hair growth by enhancing blood circulation to hair follicles and inhibiting the effects of dihydrotestosterone (DHT), a hormone linked to androgenetic alopecia. Key distinguishing characteristics of methylxanthines include their ability to act as phosphodiesterase inhibitors, which may lead to increased levels of cyclic AMP, a molecule that plays a role in cellular signaling and hair follicle function.

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    Research 30 of 91

    1. Pentoxifylline-Loaded Liposome Development, Characterization, and In Vitro Release Kinetics: Box-Behnken Design-Based Optimization. 2026
    2. Chronic Stress Suppresses the Expression of Cutaneous Hypothalamic–Pituitary–Adrenocortical Axis Elements and Melanogenesis PLoS ONE · 2014 · 40 citations
    3. Nuclear Factor I-C promotes proliferation and differentiation of apical papilla-derived human stem cells in vitro Experimental Cell Research · 2015 · 24 citations
    4. Hydrogel from Acellular Porcine Adipose Tissue Accelerates Wound Healing by Inducing Intradermal Adipocyte Regeneration Journal of Investigative Dermatology · 2018 · 23 citations
    5. Induction of Skin-Derived Precursor Cells from Human Induced Pluripotent Stem Cells PLOS ONE · 2016 · 21 citations
    6. Topical use of systemic drugs in dermatology: A comprehensive review 2011 · 19 citations
    7. Enhanced viability and neural differential potential in poor post-thaw hADSCs by agarose multi-well dishes and spheroid culture Human Cell · 2015 · 15 citations
    8. Ethyl acetate fraction of Eclipta alba: a potential phytopharmaceutical targeting adipocyte differentiation Biomedicine & Pharmacotherapy · 2017 · 13 citations
    9. NFIC promotes the vitality and osteogenic differentiation of rat dental follicle cells Journal of Molecular Histology · 2019 · 11 citations
    10. Demethylation of ITGAV accelerates osteogenic differentiation in a blast-induced heterotopic ossification in vitro cell culture model Bone · 2018 · 11 citations
    11. Anti-aging effects of black raspberry extract on cataract, alopecia, skin whitening, and weight loss Functional Foods in Health and Disease · 2018 · 10 citations
    12. Enrichment and Characterization of Human Dermal Stem/Progenitor Cells by Intracellular Granularity Stem Cells and Development · 2013 · 10 citations
    13. The local hypothalamic–pituitary–adrenal axis in cultured human dermal papilla cells BMC Molecular and Cell Biology · 2020 · 9 citations
    14. Kojyl Cinnamate Ester Derivatives Increase Adiponectin Expression and Stimulate Adiponectin-Induced Hair Growth Factors in Human Dermal Papilla Cells International Journal of Molecular Sciences · 2019 · 9 citations
    15. Autoimmune thyroid disease and human health: a systematic review of Mendelian randomization studies Frontiers in Immunology · 2025 · 4 citations
    16. Potential Lipolytic Effect of Panduratin A Loaded Microspicule Serum as a Transdermal Delivery Approach for Subcutaneous Fat Reduction Biological and Pharmaceutical Bulletin · 2023 · 4 citations
    17. Hormones Elsevier eBooks · 2018 · 4 citations
    18. YAP1 promotes adipogenesis by regulating the negative feedback mechanism of the Hippo signaling pathway via LATS2 动物学研究 · 2025 · 2 citations
    19. Sprayable supramolecular hydrogel with minimalism for wilderness first aid: integration of mechanical performance and biofunctionality Collagen and Leather · 2026
    20. Autoimmunity and clinical pathology amelioration in SLE by Dexamethasone primed Mesenchymal Stem Cell derived conditioned media 2024
    21. MEF/KSF‑conditioned culture medium: An effective method for<i>in vitro</i>culture of mouse dermal papilla cells with osteogenic differentiation potential Experimental and Therapeutic Medicine · 2021
    22. Equine adipose tissue derived stem cells and their multilineage differentiation Kocatepe Veterinary Journal · 2020
    23. 皮膚組織の再生に向けた皮膚由来幹細胞に関する研究 Institutional Repositories DataBase (IRDB) · 2014
    24. The in vitro plasticity of hair follicle dermal and mesenchymal stem cells Durham e-Theses (Durham University) · 2008
    25. Hair follicle-derived epithelial sheet has potential in vitiligo treatment medRxiv · 2026
    26. Hair growth promoting effects of adipose tissue-derived stem cells Journal of Dermatological Science · 2009 · 81 citations
    27. Human Macrophages Preferentially Infiltrate the Superficial Adipose Tissue International Journal of Molecular Sciences · 2018 · 18 citations
    28. A missense mutation in the P2RY5 gene leading to autosomal recessive woolly hair in a Syrian patient Journal of Dermatological Science · 2009 · 13 citations
    29. Untersuchungen der Fremdstoffbindung in permanenten Keratinozyten- und Melanozyten-Zelllinien sowie die Eignung von Primärkulturen aus humanen Haarfollikeln zur In-vitro-Messung der Fremdstoffaufnahme im Haar Carl von Ossiezky University of Oldenburg · 2006
    30. INTERACTION OF α-MELANOCYTE-STIMULATING HORMONE, MELATONIN, CYCLIC AMP AND CYCLIC GMP IN THE CONTROL OF MELANOGENESIS IN HAIR FOLLICLE MELANOCYTES IN VITRO Journal of Endocrinology · 1981 · 53 citations