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The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

New methods to make oxasteroids show promise for medical treatments like osteoporosis and breast cancer.

The TCL1 transgenic mouse model is useful for understanding human B-cell leukemia and testing new treatments.

The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.

New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.

Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.

Wnt7a protein is crucial for development and tissue maintenance and plays varying roles in diseases and potential treatments.

Two compounds from Asiasarum heterotropoides roots show potential as lung cancer treatments without harming normal cells.

Good feather growth in poultry needs the right balance of proteins, amino acids, minerals, and vitamins.

Different stem cells have benefits and challenges for tissue repair, and more research is needed to find the best types for each use.

Nuclear shape and chromatin changes affect gene expression in skin cell differentiation.

Heavy metals like arsenic, cadmium, and lead can increase cancer risk and worsen outcomes.

People with pattern hair loss have higher polyamine levels in the top of their head compared to the back.

The hair follicle dermal sheath is essential for hair shedding and needs to communicate with the outer root sheath for normal hair growth cycles.

Understanding skin patterns can help us learn about skin diseases and their treatments.

Some vitamins and minerals like vitamin D and iron can help with certain types of hair loss, but more research is needed for others.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

New treatments for male hypogonadism are effective and should be personalized.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Sex hormones, especially estradiol, can change chicken feather shapes and colors.

Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.

The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.

Epigenetic factors play a crucial role in skin health and disease.

Identified genes linked to male-pattern baldness may help develop new treatments.

Epigenetic mechanisms control skin development by regulating gene expression.

scINSIGHT accurately identifies cell clusters and gene patterns in complex data.