Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that the yeast androgen screen (YAS) could detect the activity of methyltestosterone in urine for a longer period than classical GC/MS, potentially identifying long-lasting metabolites.

This study found that activating CB1 receptor signaling in human hair follicles increased stem cell proliferation while reducing differentiated cell survival, suggesting CB1's role as a survival stimulus for epithelial stem cells.

This review discusses the analysis of pharmaceutical relics from prehistoric times to the twentieth century and emphasizes the need for a multifaceted approach, but it presents no new experimental results.

Certain variations of the HDAC9 gene can increase or decrease stroke risk in the Chinese population.

In this study, researchers found that ginsenoside Re from Panax ginseng increased hair shaft length and duration in mice, comparable to minoxidil, by modulating TGF-β signaling pathways.

This study identified a new lignan and 21 known compounds from Asiasarum heterotropoides roots, with two compounds showing potential anticancer activity by influencing NO production, FOXP3 expression, and HIF-1α activity in vitro.

In this study using data from young women in West Bengal, India, the researchers identified that leptin signaling impairment, insulin resistance, and specific gene mutations significantly contribute to PCOS, with obesity commonly manifesting in affected individuals.

This study found dependencies between genetic variants and various phenotypes related to fetal and early childhood growth and neurological development in healthy infants, suggesting significant gene candidates for further investigation.

This study found that inhibiting 5α-reductase in molluscs provokes a specific shell morphology, suggesting gastropods might have unique 5α-reductase substrates absent in vertebrates.

This study found that flavonoids with two hydroxyl groups in their B-ring, such as sterubin and luteolin, supported the regeneration of pigmented hair after skin injury, unlike those with one hydroxyl group.

This study found that male and female chicken feather morphology and color patterns can be extrinsically modified through molting and resetting the stem cell niche during regeneration.

This study observed that direct exposure to androgens in Western clawed frogs differentially affects thyroid receptor and deiodinase gene expression in male and female tissues, offering insight into sex-specific metabolic pathway activation.

This study found that a synthetic avicequinone C analogue, 5e, was significantly more potent in inhibiting steroid 5α-reductase type 1 activity in human keratinocytes compared to the original isolated compound.

This study found that quiescent bulge stem cells, when prevented from contributing to hair follicle and epidermal regeneration, did not affect hair follicle growth or wound healing in the short term.

This review discusses the potential role of vitamin D deficiency in cardiovascular and renal diseases and suggests that supplemental vitamin D could benefit cardiovascular outcomes, especially in African American and postmenopausal women; it reports no new clinical findings.

This study describes how manipulating the actin cytoskeleton, particularly through the gelsolin family proteins, may enhance regenerative healing in mammals, suggesting potential therapeutic pathways for improved wound repair.

This study constructed a panel of pharmacokinetic and pharmacodynamic genes, revealing that current SNP chips insufficiently capture many drug-response gene variants, highlighting the need for complementary genetic approaches.

In this research, caffeine's versatile pharmacological actions were highlighted, demonstrating its stimulant, bronchodilator, diuretic, and potential anticancer effects through interactions with adenosine receptors, phosphodiesterase, and renal tubules, revealing valuable insights for drug development and therapeutic applications in medicine.

This study identified two novel genetic variants associated with Alzheimer's disease in APOE ε4 non-carriers, revealing insights into the disease's underlying regulatory mechanisms.

This study suggests that the long noncoding RNA H19 helps dermal papilla cells maintain their hair follicle-inducing ability by activating the Wnt signaling pathway, potentially offering a therapeutic target for androgenetic alopecia.

This study found that low-level laser therapy increased the expression of proteins in dermal papilla tissues, suggesting it promotes hair growth in male androgenetic alopecia patients.

This study found that dutasteride more effectively inhibited androgen receptor signaling and reduced cell growth compared to finasteride in prostate cancer cell models, with varying sensitivities across different cell lines.

The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.

This review discusses the challenges in identifying specific hair follicle antigens involved in initiating alopecia areata and highlights the need for further research to understand its etiopathogenesis, reporting no new results.

This review discusses sex differences in immune response to respiratory viral infections, including SARS-CoV-2, and highlights that hormones like estrogen may provide females with better protection, but it reports no new results.

This study found a higher frequency of below normal ferritin and serum iron levels in women with melasma compared to controls, suggesting a possible association with melasma.

This study found that homocysteine-keratin accumulation in human hair increases towards the tips, linked to copper/iron-catalyzed demethylation of methionine, and may contribute to keratin damage.

In this study, basal cell carcinoma developed in Ptch-deficient mice only after chemical treatment, not skin wounding, suggesting a second unknown event is necessary for tumor formation.

This study found that the oral supplement INVERSION® Femme significantly reduced weight and hair loss and improved skin and nails in overweight women.

This review discusses the potential role of the dietary antioxidant index in reducing the risk of various diseases, including obesity-related conditions, certain cancers, osteoporosis, and mental illnesses, but calls for further studies to confirm these findings.