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60-90 / 710 resultsresearch The feasibility and utility of hair follicle sampling to measure FMRP and FMR1 mRNA in children with or without fragile X syndrome: a pilot study
Hair follicle sampling is a practical method for measuring biomarkers in children with and without Fragile X syndrome.
![CXXC5: A novel regulator and coordinator of TGF-β, BMP and Wnt signaling](/images/research/e45e8e5e-a2c6-4acc-a535-69d93c162686/small/12728.jpg)
research CXXC5: A novel regulator and coordinator of TGF-β, BMP and Wnt signaling
CXXC5 is a protein that controls cell growth and healing processes, and changes in its activity can lead to diseases like cancer and hair loss.
research Polycystic ovary syndrome (PCOS), an inflammatory, systemic, lifestyle endocrinopathy
PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.
![Role of ACE2 polymorphism in COVID-19: impact of age](/images/research/7ec3a20f-56f2-4ef9-af9e-cfb40150bbb0/small/17212.jpg)
research Role of ACE2 polymorphism in COVID-19: impact of age
Different ACE2 gene versions may affect COVID-19 impact based on age and suggest some hair loss drugs could be potential treatments.
research Associations of prenatal and postnatal exposure to perfluoroalkyl substances with pubertal development and reproductive hormones in females and males: The HOME study
PFAS exposure in adolescence may delay puberty in females.
![Stepwise acquisition of unique epigenetic signatures during differentiation of tissue Treg cells](/images/research/f481322b-e7b3-4272-8390-74186db2b23a/small/19146.jpg)
research Stepwise acquisition of unique epigenetic signatures during differentiation of tissue Treg cells
Tissue environment greatly affects the unique epigenetic makeup of regulatory T cells, which could impact autoimmune disease treatment.
![Topical Finasteride: A Comprehensive Review of Androgenetic Alopecia Management for Men and Women](/images/research/b89013e5-0cca-4709-94ad-b284f916525a/small/15713.jpg)
research Topical Finasteride: A Comprehensive Review of Androgenetic Alopecia Management for Men and Women
Topical finasteride might be a good alternative for hair loss treatment with fewer side effects, but more research is needed.
research Promoter Methylation Changes in KRT17: A Novel Epigenetic Marker for Wool Production in Angora Rabbit
Changes in KRT17 gene activity linked to wool production in Angora rabbits.
research Association between DNA Methylation in the Core Promoter Region of the CUT-like Homeobox 1 (CUX1) Gene and Lambskin Pattern in Hu Sheep
DNA methylation likely doesn't cause different lambskin patterns in Hu sheep.
![Proliferation, but Not Apoptosis, Is Associated with Distinct β-Catenin Expression Patterns in Non-Small-Cell Lung Carcinomas](/images/research/6676ebf8-f012-4594-b7be-28a61c91925f/small/33042.jpg)
research Proliferation, but Not Apoptosis, Is Associated with Distinct β-Catenin Expression Patterns in Non-Small-Cell Lung Carcinomas
Distinct β-catenin patterns are linked to cell growth, not cell death, in lung cancer.
![Fail-tests of DNA methylation clocks, and development of a noise barometer for measuring epigenetic pressure of aging and disease](/images/research/c6ae78d6-5249-45ef-828f-57ac01b15a6f/small/36381.jpg)
research Fail-tests of DNA methylation clocks, and development of a noise barometer for measuring epigenetic pressure of aging and disease
Elastic Net DNA methylation clocks are inaccurate for predicting age and health status; a "noise barometer" may better indicate aging and disease.
research Molecular characterization of HOXC8 gene and methylation status analysis of its exon 1 associated with the length of cashmere fiber in Liaoning cashmere goat
The methylation of the HOXC8 gene's exon 1 affects cashmere fiber length in goats.
![Viewpoint 1](/images/research/e57c69bc-e21b-42be-94b8-99fcefe271c2/small/15210.jpg)
research Viewpoint 1
Understanding skin patterns can help us learn about skin diseases and their treatments.
![863 Molecular basis of hair follicle donor dominance in androgenetic alopecia and sexual dimorphism of the skin](/images/research/b55eed09-0bd5-4505-8dc2-7125adeaeeee/small/4027.jpg)
research 863 Molecular basis of hair follicle donor dominance in androgenetic alopecia and sexual dimorphism of the skin
Hair loss patterns differ between males and females due to 5 master regulators and JAK-STAT signaling affects hair growth.
![Progressive Alopecia Reveals Decreasing Stem Cell Activation Probability during Aging of Mice with Epidermal Deletion of DNA Methyltransferase 1](/images/research/a4555612-d049-480f-9bd0-1d4c61de7ec0/small/19815.jpg)
research Progressive Alopecia Reveals Decreasing Stem Cell Activation Probability during Aging of Mice with Epidermal Deletion of DNA Methyltransferase 1
Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.
research Molecular characterization, expression and methylation status analysis of BMP4 gene in skin tissue of Liaoning cashmere goat during hair follicle cycle
BMP4 gene is crucial for hair follicle development in Liaoning cashmere goats.
![1334 Beyond goosebumps: Interactions between the hair follicle, the arrector pili muscle, and the sympathetic nerve during development and hair follicle regeneration](/images/research/4f249563-7b44-4999-828f-5262af59466e/small/4289.jpg)
research 1334 Beyond goosebumps: Interactions between the hair follicle, the arrector pili muscle, and the sympathetic nerve during development and hair follicle regeneration
Arrector pili muscle regulates hair follicle stem cells, DNA methylation needed for hair cycling, and Wnt/B-catenin signaling starts hair growth.
![Registrars’ Symposium: Summaries of Papers](/images/research/5e5f42f2-b120-421a-afad-513320718843/small/23425.jpg)
research Registrars’ Symposium: Summaries of Papers
Lower adrenal hormone levels may cause hair loss in postmenopausal women, certain patterns help diagnose nail cancer, and a gene variant linked to higher skin cancer risk in kidney transplant patients suggests monitoring folate levels.
![The Rotterdam Study: 2016 objectives and design update](/images/research/c244fc74-a75b-4325-bf8e-e8b46008026d/small/16165.jpg)
research The Rotterdam Study: 2016 objectives and design update
The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.
![Gelişmekte olan insan fetüslerinin ve yetişkinlerin derisinde EZH2 ekspresyonu: karşılaştırmalı bir çalışma](/images/research/f10a1710-59f7-4b53-aade-de95e2c13c3e/small/32862.jpg)
research Gelişmekte olan insan fetüslerinin ve yetişkinlerin derisinde EZH2 ekspresyonu: karşılaştırmalı bir çalışma
EZH2 levels decrease as fetuses develop and are higher in adult skin, which may affect skin growth and repair.
![Role of polymorphism of the androgen receptor gene andnon-random x chromosome inactivation in the pathogenesisof androgenic alopecia](/images/research/f9132468-ec0b-4bd9-82af-2a48be98dd3d/small/12302.jpg)
research Role of polymorphism of the androgen receptor gene andnon-random x chromosome inactivation in the pathogenesisof androgenic alopecia
Certain genes and X chromosome patterns may significantly contribute to the development of hair loss.
![The agouti mouse model: an epigenetic biosensor for nutritional and environmental alterations on the fetal epigenome](/images/research/e929994f-8e18-43de-a09f-9d92cb90671a/small/36830.jpg)
research The agouti mouse model: an epigenetic biosensor for nutritional and environmental alterations on the fetal epigenome
Diet changes can protect against harmful environmental effects on fetal development.
![Signalling couples hair follicle stem cell quiescence with reduced histone H3 K4/K9/K27me3 for proper tissue homeostasis](/images/research/edd920a8-de54-4cbd-9ab2-dda00c9533ed/small/35286.jpg)
research Signalling couples hair follicle stem cell quiescence with reduced histone H3 K4/K9/K27me3 for proper tissue homeostasis
Certain signals are important for reducing specific chemical markers on hair follicle stem cells during rest periods, which is necessary for healthy hair growth.
![Structural characterization of cyclosporin A, C and microbial bio-transformed cyclosporin A analog AM6 using HPLC–ESI–ion trap-mass spectrometry](/images/research/f2d2078e-d96b-47b1-8ab4-48995365ac75/small/23098.jpg)
research Structural characterization of cyclosporin A, C and microbial bio-transformed cyclosporin A analog AM6 using HPLC–ESI–ion trap-mass spectrometry
Researchers developed a method to identify and analyze cyclosporin compounds and their structures effectively.
![1336 The de novo DNA methyltransferase DNMT3A is required for epidermal homeostasis](/images/research/8bc46b45-f965-449e-be33-12afd40ba8c0/small/25779.jpg)
research 1336 The de novo DNA methyltransferase DNMT3A is required for epidermal homeostasis
DNMT3A is crucial for healthy skin and hair growth.
![Foxp3 Post-translational Modifications and Treg Suppressive Activity](/images/research/71984e10-c5c5-4e19-a5b1-adc0169dcd92/small/19325.jpg)
research Foxp3 Post-translational Modifications and Treg Suppressive Activity
Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.
![Proteomic tools for the investigation of human hair structural proteins and evidence of weakness sites on hair keratin coil segments](/images/research/1771addf-9860-4f1b-b779-ccbe14d9c1a9/small/29275.jpg)
research Proteomic tools for the investigation of human hair structural proteins and evidence of weakness sites on hair keratin coil segments
Hair proteins have weak spots in their α-helical segments.
![Epigenetic regulation in adult stem cells and cancers](/images/research/f482b861-d67b-436b-ae5e-3706e8884d7b/small/19810.jpg)
research Epigenetic regulation in adult stem cells and cancers
Understanding how epigenetic regulation affects stem cells is key to cancer insights and new treatments.
![LncRNA-000133 from secondary hair follicle of Cashmere goat: identification, regulatory network and its effects on inductive property of dermal papilla cells](/images/research/da53253f-3619-43d0-8bb7-267bafa6b5b1/small/19376.jpg)
research LncRNA-000133 from secondary hair follicle of Cashmere goat: identification, regulatory network and its effects on inductive property of dermal papilla cells
A newly found RNA in Cashmere goats may play a role in hair growth and development.