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Certain compounds, especially those with a propionic substituent, could potentially be new treatments for hair loss and similar disorders.

The activity of a specific rat enzyme in the prostate and epididymis is highly dependent on the acidity level.

Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.

Compound 15a was effective in inhibiting 5α-reductase.

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.

Rice bran extract caused moderate skin irritation but no eye irritation, while a diluted essence was not irritating to skin and only slightly to guinea pigs.

Researchers developed a method to measure different forms of a drug that could help treat prostate issues and hair loss, and found how these forms behave in animals.

A 5% minoxidil spray could effectively treat male baldness with fewer side effects and better patient comfort.

Water and fatty acids affect hair's surface differently based on hair damage, and models can help understand hair-cosmetic interactions.

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Testosterone's muscle-building effects do not require its conversion to DHT.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Finasteride and minoxidil together promote hair growth better than either alone.

Finasteride effectively treats male hair loss, improving growth and density.

5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.

Rats had lasting erectile problems after stopping a certain medication.

Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.

New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.

A new compound effectively inhibits human 5α-reductase 1.

Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

New compounds were made that effectively block enzymes related to prostate issues and hair loss.

Finasteride may affect PNMT, causing side effects.

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.