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The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

A simplified scoring system can effectively diagnose hirsutism in Chinese women of reproductive age.

Hirsutism is excessive male-pattern hair growth in women, often caused by hormonal imbalances, and requires ongoing treatment to manage.

Natural molecules like inositols, resveratrol, vitamins, and omega-3 fatty acids may help manage Polycystic Ovary Syndrome (PCOS), but their effects vary and need more exploration.

5-alpha-reductase inhibitors may reduce COVID-19 symptoms in bald males.

The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.

The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.

New treatments for a chronic skin condition show promise, but individualized plans are crucial due to varying responses.

More pediatric-specific research and guidelines are needed to improve hidradenitis suppurativa treatment in children and adolescents.

The study found that women with PCOS have more and larger ovarian follicles and differences in ovarian structure, but these features alone can't always diagnose PCOS.

Women with PCOS are more likely to have fatty liver disease and worse metabolic health.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Hormone treatments can help with women's skin and hair disorders, but they need careful monitoring and more research.

Doctors should know how to diagnose and treat PCOS, which often involves checking for high male hormone levels and using medications to manage symptoms.

Spironolactone is better than placebo for reducing excessive hair growth in women, but its effectiveness for acne is unclear due to small study sizes.

Curcumin may improve blood sugar levels and cholesterol in people with PCOS, but more research is needed.

Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.

Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.

Woodhouse-Sakati syndrome often causes sexual development issues, hair loss, learning disabilities, deafness, muscle contractions, limb pain, and diabetes.

Menopause affects hair and skin; more research needed for treatment.

Young women with PCOS have a higher risk of high blood pressure and metabolic syndrome, but these risks may decrease after age 40.

Activating NRF2 might help treat hair disorders by improving antioxidant defenses.

A team approach is crucial for managing PCOS, with dermatologists playing a key role.

The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.

Women with high androgen levels may have more severe COVID-19 symptoms.

Low and ultralow doses of flutamide can cause liver damage in young women with high androgen levels, regardless of dose or birth control use, with higher risk for those with higher BMI and liver enzyme levels before treatment.

Lipocalin-2 levels are higher in women with PCOS and may indicate insulin resistance.

Women with PCOS have higher levels of certain blood clotting factors, suggesting a greater risk of cardiovascular issues.

Women with PCOS have higher levels of AMH in their blood and follicles, and this can help predict their risk of overreaction to fertility treatments.

Early onset baldness in men may indicate a condition similar to PCOS, linked to heart disease, diabetes, and prostate issues.