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Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.

Finasteride doesn't improve survival in LNCaP tumor model during off-cycle of therapy.

Soy isoflavones can protect lung tissue from radiation damage.

Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Finasteride may cause kidney damage.

Hyperadrenocorticism in ferrets is linked to neutering and indoor housing, and is best treated with surgery and a deslorelin implant.

The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.

Fat cells are important for tissue repair and stem cell support in various body parts.

N-acetyl-cysteine shows promise in treating various diseases and may improve skin and hair conditions, but more research is needed on dosages and long-term effects.

Bexxar treatment led to a high response rate in patients with advanced-stage, treatment-resistant follicular lymphoma.

The same hormone can affect gene expression differently in various tissues, which could lead to new treatments for conditions like hair loss.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

More research is needed on the health effects of hormone therapy for transgender and nonbinary people.

Drinking a lot of alcohol increases the risk of prostate cancer and can worsen the condition.

Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.

Controlled delivery of specific RNA and IL-4 restored hair growth in mice with autoimmune alopecia.

Intermediate filaments are crucial for cell differentiation and stem cell function.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

The drug combination was safe and showed promise in treating advanced tumors.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.

Sex hormones affect reproduction, sexual development, and oral health, and it's important for dental practitioners to understand their effects and interactions.

BI 2536 had limited effectiveness against several advanced cancers and caused significant side effects.

New therapies are being developed that target integrin pathways to treat various diseases.

The main prostate diseases in dogs are benign growth, infections, and cancer, with various treatments ranging from drugs to surgery, but cancer treatments have limited success.