research Transforming Growth Factor-Beta in Stem Cells and Tissue Homeostasis
TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
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research Recent Discoveries and Developments of Androgen Receptor-Based Therapy for Prostate Cancer
New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.
research Prostate Cancer Update: 2007
2007 research improved understanding of prostate cancer risk, diagnosis, and treatment, but also showed the need for personalized treatment and further study on certain therapies' risks.
research Safety of Whole-Body Abrogation of the TRF1 Shelterin Protein in Wild-Type and Cancer-Prone Mouse Models
Deleting the Trf1 protein in mice is safe and may help prevent cancer without major side effects.
research Liarozole: A Novel Treatment Approach for Advanced Prostate Cancer - Results of a Large Randomized Trial Versus Cyproterone Acetate
Liarozole may be more effective than cyproterone acetate for treating advanced prostate cancer, with better PSA response and survival rates, while maintaining quality of life.
research Abstract P5-09-21: Selective Androgen Receptor Modulators (SARMs): Enobosarm as Targeted Therapy for the Treatment of Androgen Receptor-Positive Breast Cancer
Enobosarm may effectively treat androgen receptor-positive breast cancer with fewer side effects.
research Cedrol Restricts the Growth of Colorectal Cancer In Vitro and In Vivo by Inducing Cell Cycle Arrest and Caspase-Dependent Apoptotic Cell Death
Cedrol may be an effective treatment for colorectal cancer.
research Beyond DNA-Targeting in Cancer Chemotherapy: Emerging Frontiers - A Review
New cancer treatments aim to reduce side effects and improve effectiveness.
research Advances in the Management of Cutaneous Toxicities of Targeted Therapies
Targeted cancer therapies often cause skin problems that need careful management to improve patient quality of life and treatment success.
research News in Brief
Breast cancer survivors may have a higher risk of falls, tamoxifen could prevent breast cancer and deaths, new guidelines urge caution with prostate cancer therapy, and early balding in men may indicate a higher prostate cancer risk.
research Selective Androgen Receptor Modulators Negatively Regulate Triple-Negative Breast Cancer Growth and Epithelial-Mesenchymal Stem Cell Signaling
SARMs may be an effective treatment for a certain type of breast cancer by blocking cancer growth and spread.
research Vitamin D3 and Chemotherapy-Induced Alopecia
Vitamin D3 may prevent hair loss from chemotherapy, but side effects and cancer cell protection are concerns.
research Androgen Receptors And Their Biology
Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.
research Ectodysplasin Research: Where to Next?
Future research on ectodysplasin should explore its role in diseases, stem cells, and evolution, and continue developing treatments for genetic disorders like hypohidrotic ectodermal dysplasia.
research Steroidal 5α-Reductase and 17α-Hydroxylase/17,20-Lyase (CYP17) Inhibitors Useful in the Treatment of Prostatic Diseases
Certain drugs that block specific enzymes can help treat prostate diseases.
research Drug Safety Evaluation of Exemestane
Exemestane is effective and safe for treating certain breast cancers, with mild side effects, but needs more research on long-term effects.
research Trichomegaly of the Eyelashes Following Treatment with Cetuximab
Cetuximab can cause excessive eyelash growth.
research Are All Adverse Effects Undesirable? A Case of Chemotherapy-Induced Adverse Effect - An Exception!
Excessive eyelash growth from erlotinib may indicate positive tumor response and help treat madarosis.
research Inhibition of Mitochondrial Respiration Prevents BRAF-Mutant Melanoma Brain Metastasis
Stopping mitochondrial respiration can prevent brain cancer spread in skin cancer patients, and plant compound β-sitosterol could help achieve this.
research The Direct Inhibitory Effect of Dutasteride or Finasteride on Androgen Receptor Activity Is Cell Line Specific
Dutasteride and finasteride affect different cell types differently.
research Into the Redox Control: N-Acetyl-Cysteine Pleiotropic Effects from the Laboratory to Clinical Applications
N-acetyl-cysteine shows promise in treating various diseases and may improve skin and hair conditions, but more research is needed on dosages and long-term effects.
research Unexpected Autocrine Role of Vascular Endothelial Growth Factor in Squamous Cell Carcinoma
VEGF helps squamous cell carcinoma grow in ways beyond just blood vessel formation.
research Melatonin Receptors and Their Role in Human Diseases
Melatonin receptors, found in many body parts, can help treat various diseases like depression and diabetes due to their effects on inflammation, tumor progression, sleep disorders, and body mass regulation.
research Eph/Ephrin Signaling in Epidermal Differentiation and Disease
Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.
research Hedgehog Pathway Inhibitors Against Tumor Microenvironment
Hedgehog pathway inhibitors can treat certain aggressive cancers but face limitations like resistance and side effects.
research Metformin and Malignant Tumors: Not Over the Hill
Metformin, a diabetes drug, may help prevent and treat various cancers, but more research is needed.
research WNT Signaling in Disease
The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.
research The Transcriptional Co-Activator cAMP Response Element-Binding Protein-Binding Protein Is Expressed in Prostate Cancer and Enhances Androgen- and Anti-Androgen-Induced Androgen Receptor Function
A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.
research The Dihydrotestosterone Hypothesis of Prostate Cancer and Its Therapeutic Implications
The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.
research Androgenetic Alopecia and Polymorphism of the Androgen Receptor Gene (SNP rs6152) in Patients with Benign Prostate Hyperplasia or Prostate Cancer
Hair loss gene linked to prostate issues.