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New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.

Gemcitabine and paclitaxel are effective and safe as first-line treatment for metastatic breast cancer.

KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.

Tumor cell adhesion is linked to higher risk of SLN metastasis and melanoma recurrence, and a model including these factors predicts these outcomes better than one with just clinical data.

Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.

Dermatologists are crucial for managing skin side effects in metastatic melanoma patients using vemurafenib and ipilimumab.

Different types of fibroblasts play specific roles in wound healing and cancer, which could help improve treatments.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

Green tea extract helps prevent cell death and supports cell survival in hair cells exposed to a chemotherapy drug.

The document concludes that while some organisms can regenerate body parts, mammals generally cannot, and cancer progression is complex, involving mutations rather than a strict stem cell hierarchy.

Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.

Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.

The review concludes that accurate diagnosis of different types of hair loss requires proper biopsy techniques and understanding the hair growth cycle and underlying causes.

Tofacitinib helped most patients with alopecia areata regrow hair and changes in immune cells were linked to the treatment's effectiveness.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

Eyebrow loss has many causes and requires accurate diagnosis for proper treatment.

MicroRNAs play a crucial role in skin and hair health, affecting everything from growth to aging, and could potentially be used in treating skin diseases.

The document concludes that early diagnosis and treatment are crucial for managing skin diseases in ferrets.

Skin aging reflects overall body aging and can indicate internal health conditions.

The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Exosomes are important for skin health and could help diagnose and treat skin diseases.

Breast cancer skin metastases are rare, look different, and can be confused with other skin issues, so a biopsy is needed for accurate diagnosis.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Epidermal stem cells could lead to new treatments for skin and hair disorders.

An enzyme other than TNAP might be responsible for vitamin B-6 metabolism in the skin.