151 citations,
November 2018 in “International Journal of Pharmaceutics” Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.
57 citations,
January 2014 in “Cold Spring Harbor Perspectives in Medicine” Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.
19 citations,
January 2021 in “Experimental dermatology” Acne inversa is an epithelial-driven disease where inflammation is caused by cyst rupture, and treatments should focus on preventing tendril growth for better results.
Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.
16 citations,
July 2012 in “Current pharmaceutical biotechnology” New treatments for skin conditions related to the sebaceous gland are being developed based on current research.
124 citations,
December 2016 in “Pharmaceuticals” TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.
April 2020 in “International journal of clinical and diagnostic pathology” COX-2 and Bcl-2 proteins are involved in Lichen Planus.
134 citations,
February 2011 in “Development” Adam10 enzyme is crucial for healthy skin and proper Notch signaling.
68 citations,
January 2012 in “The American journal of pathology” Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.
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February 2007 in “Nature” The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.
14 citations,
October 2000 in “Genomics” Rat dermal papilla cells have unique genes crucial for hair growth.
August 2018 in “Journal of Investigative Dermatology” Centrosomes are essential for healthy skin and hair growth, and their role is different from that of cilia.
4 citations,
January 2021 in “Cell transplantation” Scientists found the best time to transplant human stem cells for hair growth is between days 16-18 when they have the right markers and growth potential.
1 citations,
October 2022 in “Annual review of cell and developmental biology” The nervous system helps control stem cell behavior and immune responses, affecting tissue repair and maintenance.
77 citations,
February 2018 in “Journal of Investigative Dermatology” TRPV3 in skin cells causes inflammation and cell death.
5 citations,
May 2021 in “EMBO journal” Cell polarity signaling controls tissue mechanics and cell fate, with complex interactions and varying pathways across species.
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September 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” MicroRNA-148a is crucial for maintaining healthy skin and hair growth by affecting stem cell functions.
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March 2023 in “International journal of molecular sciences” Keratin protein production in cells is controlled by a complex system that changes with cell type, health, and conditions like injury or cancer.
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January 2012 in “International Journal of Trichology” Sudden, unusual hair loss may indicate serious underlying health issues.
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January 2017 in “Journal of Investigative Dermatology” The Msi2 protein helps keep hair follicle stem cells inactive, controlling hair growth and regeneration.
9 citations,
August 2019 in “Experimental Cell Research” HPV genes and estradiol increase a cancer-related signaling pathway, which may be targeted for cervical cancer treatment.
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November 1996 in “Archives of Dermatology” A man's relapsed leprosy was successfully treated with the antibiotic sparfloxacin.
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March 2015 in “Oral surgery, oral medicine, oral pathology and oral radiology” Keratoacanthoma comes from hair follicle cells.
September 2018 in “Journal of the American Academy of Dermatology” Elderly patients with CCCA were all African American with low vitamin D, but no iron or zinc deficiencies, and no hormonal imbalances compared to younger patients.
5 citations,
May 2020 in “Life science alliance” Removing integrin α3β1 from hair stem cells lowers skin tumor growth by affecting CCN2 protein levels.
March 2024 in “Vestnik Rossijskogo universiteta družby narodov. Seriâ Agronomiâ i životnovodstvo” Wnt and Shh signaling are key in noggin-induced tumors, and blocking them can slow tumor growth.
June 2021 in “Scholars journal of applied medical sciences” Trichofolliculoma, a rare benign hair follicle tumor, can potentially recur.
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September 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” The meeting highlighted major advances in skin research, including new findings on skin microbes, genetic links to skin diseases, and improved treatments for various conditions.
139 citations,
November 2015 in “Journal of Advanced Research” Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.
25 citations,
November 2016 in “Progress in Biophysics & Molecular Biology” R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.